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SAB4700744

Sigma-Aldrich

Monoclonal Anti-STRO-1 antibody produced in mouse

clone STRO-1, purified immunoglobulin, buffered aqueous solution

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NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

STRO-1, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/mL

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable

isotype

IgM

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

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This Item
SAB4701109MAB4315SAB4701067
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

-

species reactivity

human, primate

species reactivity

-

clone

STRO-1, monoclonal

clone

STRO-1, monoclonal

clone

STRO-1, monoclonal

clone

SY11B5, monoclonal

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

purified immunoglobulin

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

-

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General description

The mouse monoclonal antibody STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.

Immunogen

Human CD34 positive bone marrow cells

Biochem/physiol Actions

STRO-1 plays a vital role as a mesenchymal stem cell (MSC) marker. This 75kDa endothelial protein has a capacity to differentiate into multiple mesenchymal lineages such as hematopoiesis supportive stromal cells with a vascular smooth muscle like phenotype, as well as adipocytes, osteoblasts and chondrocytes. STRO-1 antibody has been used to separate stromal precursors from freshly aspirated bone marrow (BM) cell suspensions.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in Tris buffered saline, pH 8.0, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Mesenchymal Stem Cell Marker Stro-1 is a 75kd Endothelial Antigen
Hongxiu N, et al.
Biochemical and Biophysical Research Communications, 413(2), 353-357 (2011)
Identification of Stromal Cell Precursors in Human Bone Marrow by a Novel Monoclonal Antibody, STRO-1
Simmons P J, et al.
Blood, 78(1), 55-62 (1991)

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