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SAB5700405

Sigma-Aldrich

Anti-Phospho-PKCalpha-S319 antibody produced in rabbit

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Synonym(s):
AAG6, PKC alpha, PKC-alpha, PKCA, PRKACA, PRKCA

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

76

species reactivity

rat, mouse, human

concentration

1.2 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer319)

Gene Information

human ... PRKCA(5578)

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This Item
SAB5700404SAB5701819SAB4301254
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

-

antibody form

affinity isolated antibody

mol wt

76

mol wt

76

mol wt

-

mol wt

80 kDa

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

UniProt accession no.

P17252

UniProt accession no.

P17252

UniProt accession no.

P17252

UniProt accession no.

P17252

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General description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Immunogen

A synthetic phosphorylated peptide around S319 of human PKCalpha (NP_002728.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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