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SAB5700456

Sigma-Aldrich

Anti-Phospho-PPP1CA-T320 antibody produced in rabbit

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Synonym(s):
PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

32
37
38

species reactivity

mouse, human, rat

concentration

2.36 mg/ml

technique(s)

immunohistochemistry: 1:50-1:100
western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr320)

Gene Information

human ... PPP1CA(5499)

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This Item
SAB4502282SAB5701522WH0005500M2
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

-

antibody form

purified immunoglobulin

clone

polyclonal

clone

polyclonal

clone

monoclonal

clone

8A7, monoclonal

Gene Information

human ... PPP1CA(5499)

Gene Information

human ... PPP1CA(5499)

Gene Information

human ... PPP1CB(5500)

Gene Information

human ... PPP1CB(5500)

UniProt accession no.

P62136

UniProt accession no.

P62136

UniProt accession no.

P62140

UniProt accession no.

P62140

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General description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T320 of human PPP1CA

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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