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SAB5701801

Sigma-Aldrich

Anti-Phospho-DRP1-S637 antibody produced in rabbit

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biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

rat, mouse, human

concentration

1.51 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer637)

Gene Information

human ... DNM1L(10059)

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SAB5701802SAB5700783SAB5701599
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

technique(s)

immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

Gene Information

human ... DNM1L(10059)

Gene Information

human ... DNM1L(10059)

Gene Information

human ... DNM1L(10059)

Gene Information

human ... TFDP1(7027)

form

liquid

form

liquid

form

buffered aqueous solution

form

liquid

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

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General description

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer′s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen

A synthetic phosphorylated peptide around S637 of human DRP1 (NP_036192.2).

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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