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SAB5701803

Sigma-Aldrich

Anti-Phospho-IRF3-S386 antibody produced in rabbit

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UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human

concentration

2.28 mg/mL

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer386)

Gene Information

human ... IRF3(3661)

General description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A synthetic phosphorylated peptide around S386 of human IRF3.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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