SMB01045

Isoliquiritin

≥90% (LC/MS-ELSD)

• Synonym(s): 4-beta-D-glucopyranosyloxy-2′,4′-dihydroxy-trans-chalcone, Isoliquiritoside
• Empirical Formula (Hill Notation): C₂₁H₂₂O₉
• CAS Number: 5041-81-6
• Molecular Weight: 418.39
• MDL number: MFCD00272145
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• biological source: plant
• assay: ≥90% (LC/MS-ELSD)
• form: solid
• mol wt: 418.39
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• InChI: 1S/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1
• InChI key: YNWXJFQOCHMPCK-LXGDFETPSA-N

Description

General description

Isoliquiritin, also known as Isoliquiritoside, is a flavonoid belongs to the class of dihydrochalcones commonly available from Glycyrrhiza Sp. plants. This plant metabolite exhibits various biological activities, including antioxidant, antifungal, anti-HIV, anticancer properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens.

Features and Benefits

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable