SML3699
G140
≥98% (HPLC)
Synonym(s):
1-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone, T015T-010-1
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C17H16Cl2N4O2
CAS Number:
Molecular Weight:
379.24
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Substrate site-targeting, non-cytotoxic, potent and selective human cyclic GMP-AMP synthase (cGAS) inhibitor against cellular STING signaling.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
Nature Communications, 10(1), 2261-2261 (2019)
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