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LiChrosorb® RP-8 (5 µm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

TM=["LiChrospher"] C8 HPLC column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

LiChrosorb® RP-8 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

Quality Level

agency

suitable for USP L7

product line

LiChrosorb®

feature

endcapped: no

manufacturer/tradename

LiChrosorb®

packaging

1 ea of

extent of labeling

9.5% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

25 cm × 4.6 mm

surface area

300 m2/g

matrix

octyl
fully porous particle

matrix active group

C8 (octyl) phase

particle size

5 μm

pore size

100 Å

operating pH

2-7.5

separation technique

reversed phase

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General description

LiChrosorb® RP-8 HPLC column is used for the separation of neutral, acidic and weakly basic compounds.

Application


  • Determination of amphotericin B, liposomal amphotericin B, and amphotericin B colloidal dispersion in plasma by high-performance liquid chromatography.: Utilizing the LiChrospher® RP-8 HPLC Column, this study develops a method for analyzing various formulations of amphotericin B in plasma, crucial for monitoring therapeutic levels and preventing toxicity in patients undergoing antifungal treatment (Egger et al., 2001).

  • Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.: This research demonstrates the application of the LiChrospher® RP-8 HPLC Column in the quantification of doxorubicin and its metabolites, enhancing the understanding of its pharmacokinetics and aiding in the optimization of cancer treatment regimens (van Asperen et al., 1998).

  • Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography.: Employing the LiChrospher® RP-8 HPLC Column, this method provides accurate and reliable quantification of glibenclamide, a critical component in managing diabetes mellitus (Valdes Santurio and Gonzalez Porto, 1996).

  • Simultaneous determination of ampicillin and metampicillin in biological fluids using high-performance liquid chromatography with column switching.: Highlighting the versatility of the LiChrospher® RP-8 HPLC Column, this study develops a technique for the simultaneous determination of ampicillin and its prodrug, metampicillin, crucial for effective antibiotic therapy monitoring (Lee et al., 1995).

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Legal Information

LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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