PHL82372

Catechol

phyproof^® Reference Substance

• Synonym(s): Pyrocatechol, 1,2-Benzenediol, 1,2-Dihydroxybenzene, 2-Hydroxyphenol, Catechol
• Linear Formula: C₆H₄-1,2-(OH)₂
• CAS Number: 120-80-9
• Molecular Weight: 110.11
• Beilstein/REAXYS Number: 471401
• MDL number: MFCD00002188
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• vapor density: 3.8 (vs air)
• vapor pressure: 1 mmHg ( 75 °C); 10 mmHg ( 118.3 °C)
• product line: phyproof^® Reference Substance
• assay: ≥95.0% (GC)
• form: flakes
• manufacturer/tradename: PhytoLab
• bp: 245 °C (lit.)
• mp: 100-103 °C (lit.)
• SMILES string: Oc1ccccc1O
• InChI: 1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H
• InChI key: YCIMNLLNPGFGHC-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Engineering cascade biocatalysis in whole cells for syringic acid bioproduction.: This study explores the use of whole-cell biocatalysis to enhance the production of syringic acid, a derivative of catechol, highlighting its potential in sustainable bio-manufacturing processes (Liu et al., 2024).



• Proteomics and metabolomics analysis of the lignin degradation mechanism of lignin-degrading fungus Aspergillus fumigatus G-13.: This research explores how catechol contributes to the degradation of lignin, an essential process for biofuel production and environmental management (Zhu et al., 2023).



• An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (M_pro) of SARS-COV-2 from crude natural extracts.: This study utilizes catechol derivatives to identify inhibitors against SARS-COV-2, providing a foundation for developing new antiviral drugs (Baron et al., 2023).



• Synthesis of soluble melanin nanoparticles under acidic conditions using Burkholderia cepacia tyrosinase and their characterization.: This article explores the synthesis of melanin nanoparticles using catechol as a substrate, showing potential applications in biomedical fields such as imaging and drug delivery (Kim et al., 2022).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• pictograms: GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H301 + H311,H315,H317,H318,H341,H350
• pcodes: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: 260.6 °F - closed cup
• flash_point_c: 127 °C - closed cup