1663700

Thiostrepton

United States Pharmacopeia (USP) Reference Standard

• Empirical Formula (Hill Notation): C₇₂H₈₅N₁₉O₁₈S₅
• CAS Number: 1393-48-2
• Molecular Weight: 1664.89
• MDL number: MFCD00135828
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• API family: thiostrepton
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule); pharmaceutical
• storage temp.: −20°C
• InChI key: NSFFHOGKXHRQEW-AIHSUZKVSA-N

Description

General description

Thiostrepton is a thiopeptide antibiotic produced by Streptomyces species, exhibiting bacteriostatic activity by binding to the 50S ribosomal subunit. It is primarily used in veterinary medicine. The USP standard enables assay validation and structural confirmation using chromatographic techniques.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Thiostrepton USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Nystatin, Neomycin Sulfate, Thiostrepton, and Triamcinolone Acetonide Cream
• Nystatin, Neomycin Sulfate, Thiostrepton, and Triamcinolone Acetonide Ointment

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable