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Showing 1-30 of 149 results for "1102974" within Papers
Leandra Naira Z Ramalho et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 74, 270-278 (2014-12-03)
Rosmarinic acid (RosmA) demonstrates antioxidant and anti-inflammatory properties. We investigated the effect of RosmA on liver ischemia/reperfusion injury. Rats were submitted to 60 min of ischemia plus saline or RosmA treatment (150 mg/kg BW intraperitoneally) followed by 6 h of reperfusion. Hepatocellular injury
Wanzhen Li et al.
The Analyst, 139(16), 3926-3931 (2014-06-21)
A thin film consisting of highly ordered and vertically oriented silica mesochannels (SMCs) was prepared on the indium tin oxide (ITO) coated glass electrode surface by chronopotentiometry. The mesochannel has a uniform pore size of 2-3 nm in diameter and
Ali Modir-Rousta et al.
Electrophoresis, 36(7-8), 1016-1023 (2015-02-03)
We recently introduced a pressure-assisted sweeping-reversed migration-EKC (RM-EKC) method for preconcentration of neutral polar N-nitrosamines with low affinity for the micellar phase. The type of surfactant and phase ratio are dominant factors in dictating the magnitude of interactions between analyte
Cristian C Villa et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(14), 3097-3109 (2014-07-22)
The behavior of water entrapped in reverse micelles (RMs) formed by two catanionic ionic liquid-like surfactants, benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD) and cetyltrimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-CTA), was investigated by using dynamic (DLS) and static (SLS) light scattering, FTIR, and (1)H NMR spectroscopy techniques.
Amie J Moyes et al.
The Journal of clinical investigation, 124(9), 4039-4051 (2014-08-12)
The endothelium plays a fundamental role in maintaining vascular homeostasis by releasing factors that regulate local blood flow, systemic blood pressure, and the reactivity of leukocytes and platelets. Accordingly, endothelial dysfunction underpins many cardiovascular diseases, including hypertension, myocardial infarction, and
Xing-You Gu et al.
G3 (Bethesda, Md.), 5(2), 183-193 (2014-12-07)
Seed dormancy is imposed by one or more of the embryo, endosperm, and maternal tissues that belong to two generations and represent two ploidy levels. Many quantitative trait loci (QTL) have been identified for seed dormancy as measured by gross
Shohda A El-Maraghy et al.
Chemico-biological interactions, 229, 26-35 (2015-02-01)
The present study investigated the gastroprotective effect of crocin in ethanol-induced gastric injury in rats. Rats were allocated into a normal group, an ulcer group, a crocin-treated group, an ulcer group pretreated with crocin, and an ulcer group pretreated with
Michael Waisberg et al.
PLoS pathogens, 10(9), e1004338-e1004338 (2014-09-12)
Invasion of mosquito salivary glands (SGs) by Plasmodium falciparum sporozoites is an essential step in the malaria life cycle. How infection modulates gene expression, and affects hematophagy remains unclear. Using Affimetrix chip microarray, we found that at least 43 genes
Marie-Hélène Ruchaud-Sparagano et al.
Immunology and cell biology, 92(9), 799-809 (2014-07-09)
Monophosphoryl lipid A (MPLA) is a lipopolysaccharides (LPS) derivative associated with neutrophil-dependent anti-inflammatory outcomes in animal models of sepsis. Little is known about the effect of MPLA on neutrophil function. This study sought to test the hypothesis that MPLA would
Abdulrazaq Bidemi Nafiu et al.
Pharmaceutical biology, 53(5), 662-671 (2014-11-29)
Carica papaya L. (Caricaceae) fruit was shown to exhibit wound healing properties. We investigated anti-inflammatory and antioxidant potential of papaya fruit phosphate-buffered saline extract (PE) during wound healing and enhancement of the potentials due to trace ions addition. Rat excision
Agha Zeeshan Mirza
Journal of drug targeting, 23(1), 52-58 (2014-08-26)
The work presented here describes the fabrication of a novel drug delivery system, which consists of gold nanorods and doxorubicin, with the attachment of thioctic acid and folic acid, for the targeted release of drug to cancer cells. Doxorubicin, the
Hadiyah N Green et al.
International journal of nanomedicine, 9, 5093-5102 (2014-11-15)
Nanoparticle (NP)-enabled near infrared (NIR) photothermal therapy has realized limited success in in vivo studies as a potential localized cancer therapy. This is primarily due to a lack of successful methods that can prevent NP uptake by the reticuloendothelial system
Koji Takeuchi et al.
Life sciences, 110(2), 77-85 (2014-07-02)
The present study compared the effects of frequently used anti-platelet drugs, such as clopidogrel, ticlopidine, and cilostazol, on the gastric bleeding and ulcerogenic responses induced by intraluminal perfusion with 25 mM aspirin acidified with 25 mM HCl (acidified ASA) in
Li-Juan Wang et al.
Oncotarget, 6(8), 5932-5946 (2015-03-25)
Intrahepatic cholangiocarcinoma (ICC) constitutes the second-most common primary hepatic malignancy. MicroRNAs (miRNAs) play important roles in the pathogenesis of ICC. However, the clinical significance of miR-21 levels in ICC remains unclear. Here, we investigated the role of miR-21 in ICC
Sandra L Orellana et al.
Journal of pharmaceutical sciences, 104(3), 1141-1152 (2015-01-06)
The association efficiency of oxytetracycline (OTC) to pharmaceutical available, ionic oil-in-water nanoemulsions is studied. Theoretical mathematical developments allowed us to differentiate by diafiltration (DF) between thermodynamically and kinetically controlled binding of the drug to the nanoemulsions, and relate these important
Anneliese Müller et al.
FEMS microbiology letters, 361(2), 166-173 (2014-10-15)
Tolerance of the foodborne pathogen Listeria monocytogenes to sublethal concentrations of disinfectants has been frequently reported. Particularly, quaternary ammonium compounds (QACs) such as benzalkonium chloride (BC) are often used in disinfectants and also as antiseptics in food industry and hospitals.
Annemie Deiteren et al.
Gut, 63(12), 1873-1882 (2014-02-25)
Substantial evidence implicates mast cells and their main constituent histamine in the pathogenesis of visceral hypersensitivity. We explored the specific contribution of histamine H4 (H4R) and H1 (H1R) receptors to visceral hypersensitivity in a postinflammatory rat model. Trinitrobenzenesulfonic acid (TNBS)-colitis
Ana L M Ivan et al.
Journal of photochemistry and photobiology. B, Biology, 138, 124-133 (2014-06-14)
Ultraviolet B (UVB) irradiation may cause oxidative stress- and inflammation-dependent skin cancer and premature aging. Pyrrolidine dithiocarbamate (PDTC) is an antioxidant and inhibits nuclear factor-κB (NF-κB) activation. In the present study, the mechanisms of PDTC were investigated in cell free
María Llorián-Salvador et al.
The Prostate, 75(1), 70-83 (2014-09-30)
Pain due to bone metastases of prostatic origin is a relevant clinical issue. We study here the nociceptive responses obtained in mice receiving the intratibial inoculation of RM1 prostate cancer cells. 10(2) -10(5) RM1 cells were inoculated to C57BL/6 mice
Xiaojun Zhou et al.
Dalton transactions (Cambridge, England : 2003), 43(31), 11834-11842 (2014-06-25)
This paper presents a facile method for the fabrication of uniform hollow mesoporous silica nanoparticles (HMSNs) with tunable shell thickness and pore size. In this method, a series of amphiphilic block copolymers of polystyrene-b-poly (acrylic acid) (PS-b-PAA) with different hydrophobic
Amjed Javid et al.
Journal of microencapsulation, 31(5), 461-468 (2014-02-06)
The present study dealt with emulsive fabrication of chitosan microcapsules encapsulating essential oils in the present of bio/surfactant. The size distribution, morphology and stability of microcapsules were examined by using advanced surface characterisation techniques. At cetyl trimethyl ammonium bromide (CTAB)
Mariángeles Noto Llana et al.
PloS one, 9(11), e111282-e111282 (2014-11-05)
Foodborne diseases caused by Salmonella enterica serovar Enteritidis (S. Enteritidis) are a significant health problem. Pregnancy, state of immunological tolerance, is a predisposing condition for the development of infections with intracellular pathogens. Salmonella species can cause pregnancy complications such as
Denusa M Veríssimo et al.
Experimental biology and medicine (Maywood, N.J.), 240(2), 175-184 (2014-09-24)
The aim of this study was to evaluate the bone regenerative effect of glutaraldehyde (GA) cross-linking on mineralized polyanionic collagen membranes in critical-sized defects on rat calvarias. Bone calvarial defects were induced in Wistar rats, which were then divided into
Jiabei Liang et al.
Scientific reports, 5, 7985-7985 (2015-01-24)
Ginseng, which is the root of Panax ginseng (Araliaceae), has been used in Oriental medicine as a stimulant and dietary supplement for more than 7,000 years. Older ginseng plants are substantially more medically potent, but ginseng age can be simulated
Anbin Zhang et al.
Transplant international : official journal of the European Society for Organ Transplantation, 27(10), 1077-1085 (2014-05-09)
Ischemia reperfusion (IR) injury is a major issue in cardiac transplantation and inflammatory processes play a major role in myocardial IR injury. Necrostatin-1 (Nec-1) is a small molecule capable of inhibiting RIP1 kinase activity and attenuates inflammation-mediated tissue injury. In
Eduardo Augusto Brosco Famá et al.
Clinica chimica acta; international journal of clinical chemistry, 437, 155-160 (2014-08-02)
Preeclampsia is a multisystem disorder whose etiology remains unclear. It is already known that circulation of soluble fms-like tyrosine kinase-1 (sFlt-1) is directly involved in pre-eclampsia development. However, the molecular mechanisms involved with sFlt-1 shedding are still unidentified. We identified
Katelyn T Gause et al.
ACS nano, 9(3), 2433-2444 (2015-02-26)
The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their inherent immunogenicity. In some cases
Hussaini Syed Sha Qhattal et al.
ACS nano, 8(6), 5423-5440 (2014-05-09)
Hyaluronan-grafted liposomes (HA-liposomes) preferentially target CD44-overexpressing tumor cells in vitro via receptor-mediated endocytosis. We investigated the pharmacokinetics and biodistribution of HA-liposomes with various sizes of HA (MW 5-8, 50-60, and 175-350 kDa) in mice. Incorporation of negatively charged HA on
Ali Akbar Asgharinezhad et al.
Analytica chimica acta, 844, 80-89 (2014-08-31)
In this study, diverse types of Fe3O4 nanocomposites modified by polyaniline, polypyrrole, and aniline-pyrrole copolymer were synthesized through chemical oxidative polymerization process for dispersive-μ-solid phase extraction (D-μ-SPE) in the presence of various dopants. The results showed that the nanocomposite modified
Cui Li et al.
Investigative ophthalmology & visual science, 55(10), 6886-6900 (2014-10-10)
To determine if IL-17 regulates Mer tyrosine kinase-positive (MerTK+) cells in Pseudomonas aeruginosa keratitis. Interleukin 17 was tested in normal and infected cornea of susceptible C57BL/6 and resistant BALB/c mice. The latter were treated with recombinant mouse (rm) IL-17; both
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