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PVA with Optimized Particle Properties - A Contribution to QbD in the Formulation of Sustained Release Tablets
,
coarse
PVA 40-88,
fine**
46 35 27
119
90
65
259
180
143
350
303
218
0 1 2 3 4 5 6 7 8 9 10 11 12
0
20
Spare parts for Mobius® FlexReady Solution with Smart Flexware® Assemblies For Chromatography and TFF
Instrumentation
XMO1/2 & XMO3 Single-Use Post-Column
Instrumentation (pH/UV/Conductivity)
117
119
122
119
123
117
122
40
7. Instrumentation
XMO1/2
User Guide-RAB1137
113
Range (%) 111-121 109-119 107-119
1:4
Average % of Expected Range 124 128 119
Range (%) 117-131 119-138 109-130
4
RAB1137pis Rev 08/24
Reproducibility
Intra-Assay CV%: <
User Guide-RAB0750
Serum 111 103-119
Plasma 103 90-119
Cell Culture Supernatants 101 90-120
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 118 114 119
Range (%) 110
Data Sheet - E1007 - Lot 016K8805
621〉
compares to standard passes
Melting range, °C
Class 1b 〈741〉
between 115° and 119° 117-119°
Specific rotation, [α]D
25
15 mg/mL in alcohol 〈781S〉
between +103° and +106°
Nano Juice™ Transfection Kit
2
3
4
1
2
4
2
3
2
4
1
1
User Guide-RAB1048
Culture Supernatants
1:2
Average % of Expected 112 111 99
Range (%) 105-119 105-117 91-106
1:4
Average % of Expected Range 119 104 111
Range (%) 111-125 98-110 102-119
4
RAB1048pis Rev 08
User Guide-RAB1188
Cell Culture Supernatants 125 119-131
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 122 119 122
Range (%) 116-127 114-127 119-125
1:4
Average % of Expected
User Guide-RAB1223
Serum 119 107-136
Plasma 105 96-117
Cell Culture Media 105 93-113
Linearity
Sample Type Serum Plasma Cell Culture Media
1:2
Average % of Expected 116 97 126
Range (%) 112-119 89-105
User Guide-RAB0548
Cell Culture Supernatants
1:2
Average % of Expected 120 119 119
Range (%) 118-128 113-123 111-127
1:4
Average % of Expected Range 111 120 120
Range (%) 103-119 109-129 113-128
4
RAB0548pis
Data Sheet - F1884 - Lot 097H888041
Ionization Mass Spectrum
40 60 80 100 120 140 160 180 200 220
0
50000
100000
150000
200000
250000
m/z
Abundance
44
56
72
89 99
109 119 127 141
User Guide-RAB1663
Range (%)
Serum 125 110-138
Plasma 119 85-149
Cell Culture Supernatants 134 119-144
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 103 105 106
Range
Data Sheet - F8763
2006
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120 140 160
Data Sheet - C6520 - Lot 041K8801
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
ProductInformation
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120
Data Sheet - F1884 - Lot 111K8811
2006
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120 140 160
Data Sheet - n5511 - Lot 041K8803
Spectrum
40 50 60 70 80 90 100 110 120 130 140 150 160 170
0
20000
40000
60000
80000
00000
20000
m/z
Abundance
42
51 55 65 67 78
84
Data Sheet - N5511 - Lot 064K8812
Storage 2-8°C.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
m/z
Abundance
41
42
55 65 78
84
Quality Control Ranges: Milliplex Canine Gut Hormone Magnetic Panel Catalog # CGTMAG-98K
Control 2 CGT-211 2286 - 5534 pg/mL
Ghrelin Control 1 CGT-111 57 - 119 pg/mL
Control 2 CGT-211 168 - 348 pg/mL
GIP
Data Sheet - C6520 - Lot 52K8801
2007
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120 140 160
Data Sheet - C6520 - Lot 41K8801
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120
Anios Application Note
chloride
Propan-2-ol, D-Gluconic acid,
compound with N,N”-Bis(4-Chlorophenyl)-
3,12-Diimino-2,4,11,13-Tetraazatetra
Decanediamidine (2:1) Amines
N-C12-14-Alkyltrimethylenedi- [10]
119
55
153
Data Sheet - L0140
Ionization Mass Spectrum
40 60 80 100 120 140 160 180 200 220 240 260 280 300
0
5000
10000
15000
20000
25000
m/z
Abundance
41
50
63
75
User Guide-RAB0695
Serum 76 68-84
Plasma 73 67-80
Cell Culture Supernatants 86 78-94
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 119 125 116
Range (%) 111-127 115
Data Sheet - F1884 - Lot 92K8802
2007
Storage 2-8°C; After opening, transfer contents to
small vial provided for your convenience.
Mattson Galaxy 3020 FT-IR
70 eV Electron Ionization Mass Spectrum
40 60 80 100 120 140 160
User Guide-RAB0541
Serum 96 81-108
Plasma 80 73-92
Cell Culture Supernatants 132 119-150
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 119 102 105
Range (%) 112-126
User Guide-RAB0672
Plasma Cell Culture Supernatants
1:2
Average % of Expected 102 102 92
Range (%) 96-108 98-108 89-95
1:4
Average % of Expected Range 123 115 119
Range (%) 119-128 106-120 110-126
4
RAB0672pis
Data Sheet - SAB4200736
e0140564 (2015).
2. Shiozawa Y., et al., J Cell Biochem., 105, 370-
80 (2008).
3. D'Souza S., et al., Blood, 119, 1888-96 (2012).
4. Svenningsson P., et al., Nat Rev Neurosci., 14,
673-80 (2013).
5.
Data Sheet-SCC468
container.
4
References
1. Nat Rev Dis Primers 2017, 3: 17022.
2. Int J Cancer 2006, 119(5): 1212-1215.
3. Genes Chromosomes Cancer
User Guide-RAB1122
Range (%)
Serum 114 106-123
Plasma 93 76-119
Cell Culture Supernatants 93 88-95
Linearity
Sample Type Serum Plasma Cell Culture Supernatants
1:2
Average % of Expected 83 87 93
Range (%)
Product Information Sheet - L1750
, Oxford,
1986) pp. 44-45.
2. The Merck Index, 12th ed., Entry# 5350.
3. Dunlop, Chemistry and Metabolism of L- and
D-Lactic Acids , Ann. N.Y. Acad. Sci., 119(3),
851-1165 (1965).
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