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Showing 1-30 of 269 results for "12257-42-0" within Site Content
NHC-based Palladium Catalysts
In collaboration with Umicore AG and Co.,1 we are pleased to offer a series of robust Pd(II) and Pd(0) complexes employed as the linchpin in C–C bond forming reactions.
Louie Group – Professor Product Portal
Professor Louie's research focuses on the discovery and mechanistic understanding of new reactions catalyzed by transition metal complexes. She has developed a highly active Ni(0) catalyst that effectively mediates a variety of cycloaddition and isomerization reactions.
3D Cell Culture with Corning Microplates
Take a deep dive into the world of 3D cell culture courtesy of Corning and understand why the Corning® spheroid microplate can be an asset in the evolution of 3D cell culture.
World ADC London
If you're planning to attend World ADC London this year, be sure to stop by booth #42 to meet the Merck team. Ask us about our expertise in conjugating drug linkers to monoclonal antibodies and the benefits it can bring
Echavarren Group – Professor Product Portal
The research of the Echavarren group centers on the development of new reactions based on the use of electrophilic complexes of Au(I), Pt(II), and other transition metals as catalysts and their applications in organic synthesis of complex, biologically active molecules.
The
MSTFA/MSTFA-d9 Derivatization of Amphetamine for GC/MS Detection and Identification
Example displays how MSTFA/MSTFA-d9 derivatization of amphetamine provides valuable information in mass spectra and chromatograms using SLB-5ms GC column.
NMR Deuterated Solvent Properties Reference Chart
Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.
Separation Options with Superdex®
Superdex® from Cytiva are Size Exclusion Chromatography media consisting of a composite base matrix of dextran and agarose. This page shows how to perform a separation with a Superdex® column.
Immunohistochemistry Applications in Gastrointestinal Cancer
Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.
Nok – Third-Generation Amphiphile for Cross-Coupling Chemistry in Water
Micellular catalysis has provided the ability to carry out several commonly used transformations used in the synthetic community to be carried out in water.
Stahl Group – Professor Product Portal
he Stahl Lab focuses on the development of catalysts and catalytic reactions for selective oxidation of organic molecules, with particular emphasis on aerobic oxidation reactions.
LRA (Lipid Removal Agent) for Biopharmaceutical Production
Lipids are naturally-occurring hydrocarbons that are poorly soluble in water and soluble in non-polar solvents such as ether and chloroform.
Pressure-Temperature Calculator for Solvents
Use the calculator to determine the boiling point or pressure of solvents based on the Antoine Equation and see solvent attributes. View a list of products based on the solvent CAS number.
Materials for Clean H2 Production from Bioethanol Reforming
Hydrogen is one of the most important resources in providing food, fuel, and chemical products for our everyday life. Sustainable catalytic hydrogen production from bioethanol has gained significant attention in recent years due to globally diminishing fossil fuel supplies, which
CRISPR-based Gene Activation
Sigma has developed a gene activation system based on a fusion of dCas9 to the catalytic histone acetyltransferase (HAT) core domain of the human E1A-associated protein p300.
Polytriarylamine Semiconductors
Polytriarylamine Semiconductors
Ngai Group – Professor Product Portal
Ngai lab focuses on the development of novel reagents and radical strategies to access open-shell reactive species for the formation of carbon-carbon and carbon-heteroatom bonds.
Bioprinting for Tissue Engineering and Regenerative Medicine
In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.
Alexanian Group - Professor Product Portal
The Alexanian group is working with Sigma-Aldrich to provide functionalized amides that enable a broad range of practical aliphatic C–H transformations. These reactions proceed in useful chemical yields with the substrate as limiting reagent under visible light or radical initiation.
Birman Group – Professor Product Portal
The main focus of research in the Birman group is on the de novo design of asymmetric catalysts and reagents. As part of this effort, they have developed Amidine-Based Catalysts, or ABCs, and demonstrated their high enantioselectivity in many asymmetric
Winter Group – Professor Product Portal
Research in the Winter lab focuses on the development of new chemical tools for biological and medical applications. Philosophically, we take the view that many problems in biology are at heart problems in mechanistic physical organic chemistry
Imprint ® DNA Modification Kit (MOD50) Protocol
The Imprint DNA Modification Kit provides the reagents needed for bisulfite conversion and post-modification clean-up of DNA samples in less than 2 hours.
Mild Mg – Halogen Exchange
Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.
Integrating Multiplex and High Sensitivity Immunoassay Detection of Alzheimer’s Disease Biomarkers
Learn how to integrate multiplex and high sensitivity immunoassay technology to further neuroscience research with MILLIPLEX® multiplex and Single Molecule Counting (SMC®) high sensitivity immunoassay detection of Alzheimer’s disease (AD) biomarkers in human cerebrospinal fluid, plasma, and serum samples.
Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk
Here we show how LC and MS methods may be optimized using a non-toxic surrogate of the ADC, an “ADC-mimic”, that behaves very similarly to the Cys-linked ADC Adcetris (Seattle Genetics).
Metal Borohydrides as Hydrogen Storage Materials
An article about metal borohydrides as hydrogen storage materials
PEPPSI™-IPent for Demanding Cross-Coupling Reactions
Professor Mike Organ and co-workers have developed the PEPPSI™ (Pyridine-Enhanced Precatalyst Preparation Stabilization and Initiation) precatalysts for palladium-catalyzed cross-coupling reactions.
Understanding Sweet Taste Perception
The powerful effect of the pleasurable sensation arising from sweet tasting foods has led to consumer demand and large-scale production of the caloric sweetening agents sucrose and fructose.
Halloysite Nanotubes Applications in Nanomaterials Research
Halloysite Nanotubes in Nanomaterials Research. Halloysite, a naturally occurring aluminosilicate nanotube, has been undeservedly forgotten.
Autophagy in Cancer Promotes Therapeutic Resistance
We presents an article on Autophagy in Cancer Promotes Therapeutic Resistance
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