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Showing 1-30 of 31 results for "127-90-2" within Papers
S A Short et al.
The Journal of biological chemistry, 271(9), 4978-4987 (1996-03-01)
The importance of eight nucleoside 2'-deoxyribosyltransferase residues for catalysis was investigated by site-directed mutagenesis. Each residue was selected because of its proximity to nucleophile Glu-98 or on its potential contribution to intrinsic protein fluorescence. Mutation of Asp-72, Asp-92, Tyr-7, Trp-12
A M Reis et al.
Cancer research, 60(6), 1571-1579 (2000-04-05)
We have examined the mutational spectrum in the Trp53 gene from UVB radiation-induced skin cancers in Trp53+/+ and Trp53+/- mutant mice of all three possible Xpc genotypes. Mutations were detected in exons 2-10 of the Trp53 coding region in approximately
Ian F Burgess et al.
BMJ (Clinical research ed.), 330(7505), 1423-1423 (2005-06-14)
To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. Randomised controlled equivalence trial. Community, with home visits. 214 young people aged 4 to 18 years and 39 adults with active head louse infestation.
T Kanda et al.
European journal of biochemistry, 197(3), 759-768 (1991-05-08)
An abundant and novel cytosolic protein was purified from the rat intestinal epithelium by gel filtration, ion-exchange and hydroxylapatite chromatography. The protein was eluted into two different positions (fractions 1 and 2) on DEAE-cellulose chromatography. We have completed the primary
N A Elshourbagy et al.
The Journal of biological chemistry, 262(17), 7973-7981 (1987-06-15)
We have isolated the human apolipoprotein (apo) A-IV gene from a cosmid library and determined its complete nucleotide sequence. The gene contains three exons of 162, 127, and 1180 nucleotides separated by two introns of 357 and 777 nucleotides. A
Fabienne Soulet et al.
The Journal of biological chemistry, 280(27), 25604-25610 (2005-05-10)
Fibroblast growth factor 2 (FGF-2) has been detected in the nuclei of many tissues and cell lines. Here we demonstrate that FGF-2 added exogenously to NIH3T3 cells enters the nucleus and interacts with the nuclear active 90-kDa ribosomal S6 kinase
Qi Fei et al.
Zhonghua yi xue za zhi, 88(37), 2597-2602 (2008-12-17)
To investigate the association of polymorphisms of PAX1 gene with congenital scoliosis (CS) in Chinese Han population and the relationship between the PAX1 gene polymorphisms and the clinical phenotypes of CS. Peripheral blood samples were collected from 127 CS patients
Aurore Bonnechère et al.
Journal of chromatography. A, 1218(29), 4627-4631 (2011-06-17)
Previous published methods for the analysis of ETU and PTU are time-consuming and furthermore use dichloromethane (DCM) for extraction or clean-up. This study details the development and validation of a rapid method that combines a simple extraction step with UHPLC-ESI(+)-MS/MS.
Anthony W Wren et al.
Macromolecular bioscience, 15(8), 1146-1158 (2015-04-30)
Silver (Ag) coated bioactive glass particles (Ag-BG) were formulated and compared to uncoated controls (BG) in relation to glass characterization, solubility and microbiology. X-ray diffraction (XRD) confirmed a crystalline AgNP surface coating while ion release studies determined low Ag release
Minna Forsman et al.
The Journal of surgical research, 146(2), 271-275 (2007-11-13)
Dupuytren's disease (DD) is a hand disease inherited as an autosomal dominant trait with variable penetrance, especially among populations of northern European ancestry. The etiology and pathophysiology of DD are not clear. The purpose of this study was to examine
Jeffery T Zobell et al.
Clinical therapeutics, 33(11), 1844-1850 (2011-10-25)
The Intermountain Cystic Fibrosis Pediatric Center utilizes ticarcillin-clavulanate 400 mg/kg/d divided every 6 hours, (maximum 24 g/d). This dosing strategy is higher than the Food and Drug Administration (FDA)-approved package labeling. We evaluated the microbiologic efficacy of this dosing regimen.
Volker Maus et al.
Cerebrovascular diseases (Basel, Switzerland), 45(1-2), 10-17 (2017-12-07)
Cerebral ischemic strokes due to extra-/intracranial tandem occlusions (TO) of the anterior circulation are responsible for causing mechanical thrombectomy (MT). The impact of concomitant contralateral carotid stenosis (CCS) upon outcome remains unclear in this stroke subtype. Retrospective analysis of prospectively
E Giladi et al.
Brain research. Molecular brain research, 7(3), 261-267 (1990-04-01)
Vasoactive intestinal polypeptide (VIP) is a regulatory neuropeptide/neurotransmitter of 28 amino acids involved in a wide variety of physiological functions. Using synthetic oligodeoxynucleotide probes related to the rat VIP-cDNA, we have isolated and characterized the gene encoding the rat pre-pro
Ali Habiballah Hassan et al.
Drug design, development and therapy, 9, 3599-3606 (2015-07-24)
The aim of this study is to utilize the biocompatibility characteristics of biodegradable polymers, viz, poly lactide-co-glycolide (PLGA) and polycaprolactone (PCL), to prepare sustained-release injectable nanoparticles (NPs) of bone morphogenetic protein-2 (BMP-2) for the repair of alveolar bone defects in
Zhiyong Yang et al.
Chemosphere, 255, 126963-126963 (2020-05-16)
Coal gasification wastewater (CGW) has attracted considerable industrial attention because of its high toxicity and poor biodegradability. Ozonation is a promising process for CGW treatment. In this study, the effects of ozone concentration, pH, and ozonation time on CGW treatment
Ivana Markova et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 20(4), 576-582 (2010-08-06)
The objectives of this study were to assess the immunohistochemical expression of p53, bcl-2, c-erbB-2, Ki-67, estrogen (ER) and progesterone (PR) receptors, matrix metalloproteinase-7 and -26 (MMP-7 and MMP-26) in endometrial cancer patients and to assess the relation between steroid
Harpreet S Sood et al.
American journal of physiology. Lung cellular and molecular physiology, 284(2), L333-L341 (2003-01-21)
To test the hypothesis that endothelial dysfunction in hyperhomocysteinemia was due to increased levels of nitrotyrosine and matrix metalloproteinase (MMP) activity in response to antagonism of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), cystathionine beta-synthase (CBS) -/+ mice were bred, tail tissue was
A Gül et al.
Genes and immunity, 3(6), 368-372 (2002-09-05)
This study aimed to analyse the association of HLA-B alleles other than -B51 with Behçet's disease (BD). We also investigated the frequency of HLA-B alleles sharing the same natural killer cell immunoglobulin-like receptor (KIR) binding sequence with HLA-B51. Broad-genotyping of
G Castaman et al.
Thrombosis research, 126(3), 227-231 (2010-07-24)
Accurate measurement of von Willebrand factor (VWF) is a critical requirement for the diagnosis of von Willebrand disease (VWD). To evaluate the diagnostic efficiency of a rapid quantitative test for the measurement of VWF antigen (VWF:Ag) in type 1 VWD.
Emily M Garland et al.
Hypertension (Dallas, Tex. : 1979), 46(5), 1103-1110 (2005-10-06)
Postural tachycardia syndrome (POTS) is a heterogeneous disorder characterized by an excessive rise in heart rate and symptoms consistent with cerebral hypoperfusion in the upright position. NO produced by endothelial NO synthase is a significant factor in the regulation of
R Griebenow et al.
Blood pressure, 6(5), 299-306 (1997-11-14)
The concept of initiating treatment of mild-to-moderate hypertension with a low-dose combination of reserpine and the thiazide clopamide in comparison to monotherapy with an ACE inhibitor was investigated. A total of 127 adult outpatients with diastolic blood pressure between 100
Ali Reza Golshayan et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27(2), 235-241 (2008-12-10)
Metastatic renal cell carcinoma (mRCC) with sarcomatoid differentiation is an aggressive disease that is associated with poor outcomes to chemotherapy or immunotherapy. The utility of vascular endothelial growth factor (VEGF)-targeted therapy in patients with this disease is unknown. Patients who
V A de Souza et al.
Journal of medical virology, 52(3), 275-279 (1997-07-01)
A measles-specific enzyme-linked immunosorbent assay (ELISA)-IgG avidity test for serologic evaluation of the efficacy of measles vaccines with only one blood sample was evaluated after vaccination with three measles vaccine strains. Avidity indices were determined by the urea elution technique
Valérie Pelletier et al.
Human mutation, 28(1), 81-91 (2006-09-14)
X-linked forms of retinitis pigmentosa (RP) (XLRP) account for 10 to 20% of families with RP and are mainly accounted for by mutations in the RP2 or RP GTPase regulator (RPGR) genes. We report the screening of these genes in
Jason L Hornick et al.
The American journal of surgical pathology, 33(4), 542-550 (2008-11-27)
INI1 (hSNF5/SMARCB1), a member of the SWI/SNF chromatin remodeling complex located on chromosome 22q11.2, is deleted or/or mutated in strictly defined malignant rhabdoid tumors (MRT) of infancy. Recent studies suggest that some epithelioid sarcomas (ES) also show inactivation of INI1.
G Napolitano et al.
Molecular endocrinology (Baltimore, Md.), 14(4), 486-505 (2000-04-19)
Transforming growth factor (TGF)-beta1-decreased major histocompatibility complex (MHC) class I gene expression in thyrocytes is transcriptional; it involves trans factors and cis elements important for hormone- as well as iodide-regulated thyroid growth and function. Thus, in rat FRTL-5 thyrocytes, TGF-beta1
Joachim Alexandre et al.
PloS one, 10(7), e0132592-e0132592 (2015-07-30)
In ST elevation myocardial infarction (STEMI) context, clinical studies have shown the deleterious effect of high aldosterone levels on ventricular arrhythmia occurrence and cardiac mortality. Previous in vitro reports showed that during ischemia-reperfusion, aldosterone modulates K+ currents involved in the
F J Morgan et al.
The Journal of biological chemistry, 250(13), 5247-5258 (1975-07-10)
The amino acid sequences of both the alpha and beta subunits of human chorionic gonadotropin have been determined. The amino acid sequence of the alpha subunit is: Ala - Asp - Val - Gln - Asp - Cys - Pro
Silke Wiedmann et al.
Diabetes, 57(1), 209-217 (2007-10-18)
Lipin, a novel molecular protein expressed by adipocytes, has marked effects on adipose tissue mass, insulin sensitivity, and glucose homeostasis. Thus, we hypothesized that genetic variants within LPIN1 are associated with traits of the metabolic syndrome. A total of 15
Rachele Berria et al.
Clinical pharmacology and therapeutics, 80(2), 105-114 (2006-08-08)
Thiazolidinediones have gained widespread use for the treatment of type 2 diabetes mellitus and other insulin resistance states, including polycystic ovary syndrome (PCOS). In thiazolidinedione-treated patients a small reduction in hemoglobin and hematocrit levels often is observed, and this generally
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