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Showing 1-30 of 30 results for "136-40-3" within Papers
G Saglio et al.
Proceedings of the National Academy of Sciences of the United States of America, 76(7), 3420-3424 (1979-07-01)
Isoelectric focusing, cellulose acetate electrophoresis, and carboxymethylcellulose chromatography in the presence of Nonidet P-40 allow the separation of pure gamma chains into two fractions. Amino acid analysis of their cyanogen bromide fragment 3 (gamma CB3) identifies these fractions as the
Emilio Fernández et al.
Antioxidants & redox signaling, 19(9), 912-918 (2013-02-20)
Nitrosative stress, where nitrosylation of tyrosine (Tyr) leading to 3-nitrotyrosine proteins or free 3-nitrotyrosine is the most prominent change, has been proposed as a pathogenic mechanism in Parkinson's disease (PD). Levels of 3-nitrotyrosine proteins in serum and cerebrospinal fluid (CSF)
Boryana Konstantinova Popivanova et al.
Cancer science, 98(3), 321-328 (2007-02-03)
We previously observed that Pim-3 with serine/threonine kinase activity, was aberrantly expressed in malignant lesions of endoderm-derived organs, liver and pancreas. Because Pim-3 protein was not detected in normal colon mucosal tissues, we evaluated Pim-3 expression in malignant lesions of
M Czerwiński et al.
European journal of biochemistry, 174(4), 647-654 (1988-07-01)
The mouse hybridoma monoclonal antibody BIII.136 of the IgG2a class is specific for human erythrocyte band-3 protein. It was shown by means of immunoblotting and immunoprecipitation assays that the antibody recognized an epitope located in the cytoplasmic pole of the
David Mateo et al.
The Journal of chemical physics, 138(4), 044321-044321 (2013-02-08)
Kohn-Sham density functional calculations are reported for the structures of clusters consisting of a carbonyl sulfide (OCS) molecule with N = 1, 8, 18, and 40 attached (3)He atoms. The N = 1 cluster ground state is highly localized at
S Kawamoto et al.
The Journal of biological chemistry, 262(13), 6280-6283 (1987-05-05)
Arginase (EC 3.5.3.1) catalyzes the last step of urea synthesis in the liver of ureotelic animals. The nucleotide sequence of rat liver arginase cDNA, which was isolated previously (Kawamoto, S., Amaya, Y., Oda, T., Kuzumi, T., Saheki, T., Kimura, S.
Jonathan A Ledermann et al.
The Lancet. Oncology, 17(11), 1579-1589 (2016-09-13)
In patients with platinum-sensitive recurrent serous ovarian cancer, maintenance monotherapy with the PARP inhibitor olaparib significantly improves progression-free survival versus placebo. We assessed the effect of maintenance olaparib on overall survival in patients with platinum-sensitive recurrent serous ovarian cancer, including
Jeong-Yeol Park et al.
Obstetrics and gynecology, 122(1), 7-14 (2013-06-08)
To estimate the oncologic and pregnancy outcomes after oral progestin treatment of women of reproductive age with stage IA endometrial adenocarcinoma with stage IA, grade 1 differentiation with superficial myometrial invasion or stage IA, grade 2-3 differentiation with or without
Zhen Wang et al.
Anticancer research, 28(3A), 1667-1674 (2008-07-18)
Noxa is a pro-apoptotic Bcl-2 homology 3 (BH3)-only containing protein. Here we report the identification of two splicing variants of the human Noxa gene, which consists of three exons and two introns. Alternative splicing of exon 2 yields three transcripts.
M Fragkos et al.
Hippokratia, 22(3), 132-136 (2018-07-01)
In women with recurrent miscarriages, up to 50 % of those cases remain unexplained. In this study, we evaluated the impact of Cytosine/Guanine/Guanine (CGG)  trinucleotide expansions of the fragile-X mental retardation 1 (FMR1) gene in women with unexplained recurrent miscarriages.
Bradley A Erickson et al.
Urology, 84(1), 213-216 (2014-05-20)
To evaluate multi-institutional outcomes of bulbar urethroplasty utilizing a standardized cystoscopic follow-up protocol. Eight reconstructive surgeons prospectively enrolled urethral stricture patients in a multi-institutional study and performed postoperative cystoscopy at 3 and 12 months. Anatomic failure was defined as the
Robert M Sharkey et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(22), 5131-5138 (2015-06-25)
This study examined the delivery of SN-38 to Trop-2-expressing tumors and assessed the constitutive products in the serum, liver, and small intestine in nude mice bearing human tumor xenografts (Capan-1 or NCI-N87) given a single injection of irinotecan (40 mg/kg;
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
C Emanueli et al.
Circulation, 100(23), 2359-2365 (1999-12-11)
The activation of B(2) receptors by kinins could exert cardioprotective effects in myocardial ischemia and heart failure. To test whether the absence of bradykinin B(2) receptors may affect cardiac structure and function, we examined the developmental changes in blood pressure
Daniella Ishimaru et al.
The Journal of biological chemistry, 285(35), 27182-27191 (2010-06-24)
The antiapoptotic Bcl-2 protein is overexpressed in a variety of cancers, particularly leukemias. In some cell types this is the result of enhanced stability of bcl-2 mRNA, which is controlled by elements in its 3'-untranslated region. Nucleolin is one of
J B Marteau et al.
Journal of thrombosis and haemostasis : JTH, 6(6), 920-927 (2008-03-28)
P-selectin is an adhesion molecule known to be involved in the pathogenesis of several diseases through its major role in the initial phase of leukocytes recruitment during inflammation. However, genetic characterization of soluble P-selectin remains unclear. In the STANISLAS cohort
A VanderWalde et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 18(8), 1273-1280 (2012-02-07)
Patients with high-risk locally advanced/inflammatory and oligometastatic (≤3 sites) breast cancer frequently relapse or experience early progression. High-dose chemotherapy combined with peripheral stem cell rescue may prolong progression-free survival/relapse-free survival (PFS/RFS) and overall survival (OS). In this study, patients initiated
Laura L Kilarski et al.
Movement disorders : official journal of the Movement Disorder Society, 27(12), 1522-1529 (2012-09-08)
Approximately 3.6% of patients with Parkinson's disease develop symptoms before age 45. Early-onset Parkinson's disease (EOPD) patients have a higher familial recurrence risk than late-onset patients, and 3 main recessive EOPD genes have been described. We aimed to establish the
Matthias M Weber et al.
Hormone research, 57(3-4), 105-112 (2002-05-15)
The liver is the main source of serum insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) and the concentration of these proteins might reflect liver function. In a retrospective longitudinal study we examined serum levels of total and free IGF-I
Toshiya Inada et al.
Pharmacogenetics and genomics, 18(4), 317-323 (2008-03-13)
Neuroleptic-induced tardive dyskinesia (TD) is an involuntary movement disorder that develops in patients who have undergone long-term treatment with antipsychotic medications, and its etiology is unclear. In this study, a genome-wide association screening was done to identify the pathway(s) in
Andreas L Petzer et al.
Wiener klinische Wochenschrift, 132(15-16), 415-422 (2020-06-14)
Several clinical trials in chronic phase (CP) chronic myeloid leukemia (CML) showed that early response to tyrosine kinase inhibitor (TKI) treatment results in an improved long-term survival and progression-free survival. This study assessed whether patients achieving early treatment response (ETR;
L P Aiello et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(13), 6231-6235 (1994-06-21)
Loss of capillary pericytes, a characteristic finding in diabetic retinopathy, is strongly associated with hyperglycemia. The pathologic aberrations associated with diabetic retinopathy are localized primarily in the retinal capillaries and are only poorly reversed by subsequent euglycemic control. Since hyperglycemia
Aneesa Noormohamed et al.
Foodborne pathogens and disease, 9(7), 617-624 (2012-05-02)
Campylobacter species are one of the leading causes of foodborne disease in the United States. Campylobacter jejuni and Campylobacter coli are the two main species that are of concern to human health, and they cause approximately 95% of human infections.
Harutoshi Matsumoto et al.
Oncology letters, 23(3), 99-99 (2022-02-15)
Musa basjoo (MB) is a species of the banana plant belonging to the genus Musa that has been used as a folk medicine. However, evidence-based biological activities and the molecular mechanism of action of MB are unknown. Thus, the aim
Matthew J Lees et al.
Nutrients, 12(7) (2020-07-16)
We investigated the effects of ingesting a leucine-enriched essential amino acid (EAA) gel alone or combined with resistance exercise (RE) versus RE alone (control) on plasma aminoacidemia and intramyocellular anabolic signaling in healthy younger (28 ± 4 years) and older
Hyo-Ju Son et al.
PloS one, 12(11), e0188860-e0188860 (2017-12-01)
Diagnosis of pneumocystis pneumonia (PCP) relies on microscopic visualization of P. jirovecii, or detection of Pneumocystis DNA in respiratory specimens, which involves invasive procedures such as bronchoalveolar lavage. The (1-3)-β-D-glucan (BG) assay has been proposed as a less invasive and
Bardia Nourbakhsh et al.
The Lancet. Neurology, 20(1), 38-48 (2020-11-27)
Methylphenidate, modafinil, and amantadine are commonly prescribed medications for alleviating fatigue in multiple sclerosis; however, the evidence supporting their efficacy is sparse and conflicting. Our goal was to compare the efficacy of these three medications with each other and placebo
R J Rathmann et al.
Journal of animal science, 87(11), 3686-3701 (2009-06-09)
Preselected carcasses (n = 112) from feedlot steers fed zilpaterol hydrochloride (ZH; 8.33 mg/kg, DM basis) in a serial slaughter experiment were evaluated to determine the effects of ZH upon carcass cutability, composition, and tenderness. A 4 x 4 factorial
Gunter von Minckwitz et al.
The Lancet. Oncology, 15(7), 747-756 (2014-05-06)
Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, trastuzumab, and a platinum salt for HER2-positive breast cancer. We therefore aimed to assess the efficacy
Niels Wcj van de Donk et al.
The Lancet. Haematology, 5(10), e479-e492 (2018-10-07)
In patients with recently diagnosed multiple myeloma, the HOVON-50 phase 3 trial showed improved event-free survival for thalidomide-containing induction and maintenance regimens (in conjunction with high-dose melphalan and autologous stem cell transplantation [auto-SCT]) after a median of 52 months of
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