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Showing 1-30 of 96 results for "1491300" within Papers
Weiyun Qian et al.
The Journal of clinical endocrinology and metabolism, 99(12), 4683-4689 (2014-09-19)
Oxytocin can affect energy homeostasis and has interesting potential as a metabolic disease therapeutic. We detected serum oxytocin levels in obese (OB) and type 2 diabetes mellitus (T2DM) subjects and investigated the relationships between serum oxytocin levels and glycolipid metabolism
Wensi Tao et al.
PloS one, 9(10), e110737-e110737 (2014-11-02)
Disabled-2 (Dab2) is a widely expressed endocytic adaptor that was first isolated as a 96 KDa phospho-protein, p96, involved in MAPK signal transduction. Dab2 expression is lost in several cancer types including breast cancer, and Dab2 is thought to have
Valéria Ernestânia Chaves et al.
Peptides, 45, 9-14 (2013-05-01)
The basic mechanisms that lead obesity are not fully understood; however, several peptides undoubtedly play a role in regulating body weight. Obesity, a highly complex metabolic disorder, involves central mechanisms that control food intake and energy expenditure. Previous studies have
Mercè Masana et al.
Psychoneuroendocrinology, 48, 98-110 (2014-07-08)
Understanding the molecular mechanisms by which stress is translated into changes in complex behavior may help to identify novel treatment strategies for stress-associated psychiatric disorders. The tumor suppressor gene down-regulated in renal cell carcinoma 1 (DRR1) was recently characterized as
Picklu Chaudhuri et al.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 128(1), 48-52 (2014-10-04)
To evaluate whether a combination of misoprostol and oxytocin more effectively reduces blood loss during and after cesarean delivery than does oxytocin alone among women with known risk factors for postpartum hemorrhage (PPH). A prospective, randomized, double-blind, placebo-controlled trial was
A secondary analysis of a randomized placebo-controlled trial comparing the analgesic effects of oxytocin with carbetocin: postcesarean delivery morphine equivalents.
Ewa Gawecka et al.
Anesthesia and analgesia, 119(4), 1004-1004 (2014-09-19)
Reihane Seifi Moroudi et al.
Molecular biology reports, 41(12), 8019-8030 (2014-09-07)
One of the important behaviors of dogs is trainability which is affected by learning and memory genes. These kinds of the genes have not yet been identified in dogs. In the current research, these genes were found in animal models
Michael E McCullough et al.
Neuroscience and biobehavioral reviews, 37(8), 1485-1492 (2013-05-15)
Research on the neurobiological and behavioral effects of oxytocin (OT), as well as on its possible therapeutic applications, has intensified in the past decade. Accurate determination of peripheral OT levels is essential to reach meaningful conclusions and to motivate, support
Ageing research: Blood to blood.
Megan Scudellari
Nature, 517(7535), 426-429 (2015-01-23)
Denis J Crankshaw et al.
Life sciences, 116(1), 25-30 (2014-09-10)
Methyl palmitate is thought to cause relaxation in vascular smooth muscle by opening voltage-activated potassium channels. We have tested the hypothesis that methyl palmitate, a putative regulator from perivascular fat, is an inhibitor of the contractility of human pregnant myometrium
Sara Kenyon et al.
The Cochrane database of systematic reviews, 7(7), CD007201-CD007201 (2013-07-16)
A major cause of failure to achieve spontaneous vaginal birth is delay in labour due to presumed inefficient uterine action. Oxytocin is given to increase contractions and high-dose regimens may potentially increase the number of spontaneous vaginal births, but as
Oliver J Bosch
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1631), 20130085-20130085 (2013-10-30)
The most significant social behaviour of the lactating mother is maternal behaviour, which comprises maternal care and maternal aggression (MA). The latter is a protective behaviour of the mother serving to defend the offspring against a potentially dangerous intruder. The
Guillaume E Beranger et al.
Endocrinology, 155(4), 1340-1352 (2014-02-11)
Osteoporosis and overweight/obesity constitute major worldwide public health burdens that are associated with aging. A high proportion of women develop osteoporosis and increased intraabdominal adiposity after menopause. which leads to bone fractures and metabolic disorders. There is no efficient treatment
J Li et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(1), 51-62 (2014-10-28)
Oxytocin plays an analgesic role in modulation of nociception and pain. Most work to date has focused on the central mechanisms of oxytocin analgesia, but little is known about whether peripheral mechanisms are also involved. The mesenteric afferent discharge was
Genichiro Sumi et al.
Journal of natural medicines, 68(3), 550-560 (2014-04-18)
We previously reported that shakuyaku-kanzo-to, a kampo medicine consisting of shakuyaku and kanzo, has an inhibitory effect on myometrial contractions in pregnant women. In this study, we evaluated the effects of kanzo, glycyrrhizin (a major component of kanzo), glycyrrhetinic acid
Elizabeth C Finger et al.
Neurology, 84(2), 174-181 (2014-12-17)
To determine the safety and tolerability of 3 doses of intranasal oxytocin (Syntocinon; Novartis, Bern, Switzerland) administered to patients with frontotemporal dementia (FTD). We conducted a randomized, parallel-group, double-blind, placebo-controlled study using a dose-escalation design to test 3 clinically feasible
Chiharu Kanamori et al.
European journal of obstetrics, gynecology, and reproductive biology, 178, 142-147 (2014-05-06)
Although smoking is the most important modifiable risk factor associated with preterm delivery, the underlying mechanism by which smoking stimulates premature uterine contractions is still poorly understood. In the present study, we investigated whether cigarette smoking affects the contractile sensitivity
J D Woolley et al.
Psychoneuroendocrinology, 53, 217-222 (2015-02-01)
Olfaction plays an important role in mammalian social behavior. Olfactory deficits are common in schizophrenia and correlate with negative symptoms and low social drive. Despite their prominence and possible clinical relevance, little is understood about the pathological mechanisms underlying olfactory
Anna L MacKinnon et al.
Psychoneuroendocrinology, 48, 52-63 (2014-07-06)
The present longitudinal study examined the relations between plasma oxytocin, theory of mind, and maternal interactive behavior during the perinatal period. A community sample of women was assessed at 12-14 weeks gestation, 32-34 weeks gestation, and 7-9 weeks postpartum. Oxytocin
R Decaluwé et al.
The Veterinary record, 174(15), 381-381 (2014-02-27)
Farrowing induction in sows is frequently applied and different protocols were described. Most studies induce farrowing between day 111 and 113 of gestation, but hardly any later during gestation. The aim of this study was to investigate the effects of
Guadalupe Delgado et al.
Thyroid : official journal of the American Thyroid Association, 25(3), 352-360 (2015-02-11)
Iodine is a crucial component of thyroid hormones, and several reports have shown that iodine per se is implicated in the physiopathology of other organs. Innovative ion chromatography detection following a four-step temperature ramp microwave digestion in 25-50 mM nitric acid
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(3), 3366-3366 (2013)
Jennifer S Mascaro et al.
Psychoneuroendocrinology, 46, 153-163 (2014-06-03)
Despite the well-documented importance of paternal caregiving for positive child development, little is known about the neural changes that accompany the transition to fatherhood in humans, or about how changes in hormone levels affect paternal brain function. We compared fathers
Michael S Sinclair et al.
Physiology & behavior, 141, 103-110 (2015-01-03)
Oxytocin (OXT) suppresses food intake and lack of OXT leads to overconsumption of sucrose. Taste bud cells were recently discovered to express OXT-receptor. In the present study we tested whether administering OXT to wild-type mice affects their licking behavior for
Oxytocin and vasopressin: social neuropeptides with complex neuromodulatory functions.
Eduardo E Benarroch
Neurology, 80(16), 1521-1528 (2013-04-17)
Yoshie S Weems et al.
Theriogenology, 82(3), 440-446 (2014-06-09)
The objective of this study was to determine whether PGE1 or PGE2 prevents a premature luteolysis when oxytocin is given on Days 1 to 6 of the ovine estrous cycle. Oxytocin given into the jugular vein every 8 hours on
Rana Mroue et al.
Developmental biology, 399(1), 15-26 (2014-12-17)
Intercellular communication is essential for glandular functions and tissue homeostasis. Gap junctions couple cells homotypically and heterotypically and co-ordinate reciprocal responses between the different cell types. Connexins (Cxs) are the main mammalian gap junction proteins, and the distribution of some
Hsin-Jung Wu et al.
Mechanisms of development, 136, 73-86 (2015-02-15)
In mammals, some sites of specialized skin such as the palms, soles, and lips grow proportionally with the animal. However, other types of specialized skin such as the nipple and anal/genital region are dramatically altered with changes of reproductive status.
Kimberly H Cox et al.
Psychoneuroendocrinology, 51, 271-281 (2014-12-03)
Sex differences in behavior are widespread and often caused by hormonal differences between the sexes. In addition to hormones, the composition and numbers of the sex chromosomes also affect a variety of sex differences. In humans, X-chromosome genes are implicated
Oxytocin and behavior: evidence for effects in the brain.
Francis L Stevens et al.
The Journal of neuropsychiatry and clinical neurosciences, 25(2), 96-102 (2013-05-21)
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