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Showing 1-17 of 17 results for "151-21-3" within Papers
Heae Surng Park et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(9), 1212-1222 (2014-01-11)
Epidermal growth factor receptor (EGFR) is frequently overexpressed in triple-negative breast cancer and is emerging as a therapeutic target. EGFR gene copy number alteration and mutation are highly variable and scientists have been challenged to define their prognostic significance in
Lauren Averett Byers et al.
Oncotarget, 8(46), 81441-81454 (2017-11-09)
Amuvatinib (MP-470) is a multi-targeted kinase inhibitor with potent activity against c-Kit, synergistic with DNA-damaging agents. We evaluated amuvatinib in combination with platinum-etoposide (EP) chemotherapy by objective response rate, survival, and tolerability in platinum-refractory small cell lung cancer (SCLC) patients.
Chun-Liang Chen et al.
BMC cancer, 7, 111-111 (2007-06-30)
Stat3 has been classified as a proto-oncogene and constitutive Stat3 signaling appears to be involved in oncogenesis of human cancers. However, whether constitutive Stat3 signaling plays a role in the survival and growth of osteosarcomas, rhabdomyosarcomas, and soft-tissue sarcomas is
Derek L Stirewalt et al.
Blood, 107(9), 3724-3726 (2005-12-22)
FLT3 internal tandem duplications (FLT3/ITDs) in the juxtamembrane domain are found in approximately 25% of acute myeloid leukemia (AML) patients, ranging in size from 3 to hundreds of nucleotides. We examined whether the sizes of FLT3/ITDs were associated with clinical
Chao-Bin Yeh et al.
European journal of medicinal chemistry, 45(9), 3981-3985 (2010-08-10)
Previous research indicates that cantharidin, norcantharidin and their analogues exhibit anticancer activity due to their inhibition of cancer cell lines such as HL60, HT29 and L1210. The anticancer activities of cantharidin, norcantharidin and their analogues involve the suppression of serine/threonine
H Fakhim et al.
Journal de mycologie medicale, 30(3), 100966-100966 (2020-04-23)
Candida africana has been recovered principally as a causative agent of vulvovaginal candidiasis (VVC) from different countries, which is likely to be misidentified as the typical Candida albicans or Candida dubliniensis. The current study aimed to characterize C. albicans species complex obtained from
Antonio Di Stefano et al.
Journal of medicinal chemistry, 48(7), 2646-2654 (2005-04-02)
The present work reports the synthesis of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes (4a-f, 5a-f) as a continuation of our studies to better understand the significance of the halo substituent in the trans-1-phenyl-2-aminoindane series and to extend knowledge of the monophenolic ligands of DA receptors.
Sayaka Nose-Ogura et al.
Scandinavian journal of medicine & science in sports, 30(8), 1379-1386 (2020-04-15)
The effects of transdermal estradiol treatment (HT) in amenorrheic athletes (AA) with low body weight (BW) and low bone mineral density (BMD) are unknown. To investigate whether HT increases BMD in AA with low BW and to compare the results
Jan M Williams et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 302(10), R1209-R1218 (2012-03-24)
This study examined whether substitution of chromosome 5 containing the CYP4A genes from Brown Norway rat onto the Dahl S salt-sensitive (SS) genetic background upregulates the renal production of 20-HETE and attenuates the development of hypertension. The expression of CYP4A
Susana Aidé et al.
Journal of lower genital tract disease, 16(2), 133-139 (2012-03-01)
The purpose of this study was to discuss our investigation of the hypermethylation of promoter regions of tumor suppressor genes, such as death-associated protein kinase (DAPK) and p16, in vulvar lichen sclerosus (LS), in comparison with a control group. Promoter
Victor Dishy et al.
Pharmacogenetics, 14(8), 517-522 (2004-07-31)
The uncommon Thr164Ile polymorphism of the beta2-adrenoceptor is associated with profoundly altered responses to agonist in vitro; however its effects on vascular responses in vivo are not known. Altered adrenergic vascular sensitivity may contribute to the decreased survival observed in
Danai-Dionysia Fourla et al.
Cellular signalling, 24(12), 2315-2328 (2012-08-28)
Previous studies have shown that the intracellular domains of opioid receptors serve as platforms for the formation of a multi-component signaling complex consisting of various interacting partners (Leontiadis et al., 2009, Cell Signal. 21, 1218-1228; Georganta et al., 2010, Neuropharmacology
Marimuthu Ragavan Ramesh Kumar et al.
Microbial drug resistance (Larchmont, N.Y.), 23(5), 602-608 (2016-11-18)
The antibiotic, trimethoprim-sulfamethoxazole (TMP-SMX), is generally used for prophylaxis in HIV individuals to protect them from Pneumocystis jiroveci infection. Long-term use of TMP-SMX develops drug resistance among bacteria in HIV patients. The study was aimed to detect the TMP-SMX resistance
Andrea G Edlow et al.
American journal of obstetrics and gynecology, 213(1), 59-59 (2015-03-17)
'Omics analysis of large datasets has an increasingly important role in perinatal research, but understanding gene expression analyses in the fetal context remains a challenge. We compared the interpretation provided by a widely used systems biology resource (ingenuity pathway analysis
Kayo Nishimatsu et al.
Annals of nuclear medicine, 29(9), 766-771 (2015-07-15)
In positron emission tomography (PET) with F-18-fluorodeoxyglucose (FDG), non-tumorous focal uptake is often observed around the lumbar spinous processes (LSPs). Close approximation of LSPs with sclerosis is often seen, which is called Baastrup disease. The aim of this study was
M C Brown et al.
The Journal of cell biology, 135(4), 1109-1123 (1996-11-01)
Paxillin is a 68-kD focal adhesion phosphoprotein that interacts with several proteins including members of the src family of tyrosine kinases, the transforming protein v-crk, and the cytoskeletal proteins vinculin and the tyrosine kinase, focal adhesion kinase (FAK). This suggests
Akira Tsuburaya et al.
The Lancet. Oncology, 15(8), 886-893 (2014-06-24)
The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant Multi-Institutional group Trial (SAMIT) to assess the superiority of sequential treatment (paclitaxel then tegafur and uracil [UFT] or paclitaxel then
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