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Data Sheet - N9036
Notch-3/Fc
chimera, generated by the proteolytic removal of the
signal peptide, is a disulfide-linked homodimeric
protein. Based on N-terminal sequencing, mature
Notch-3/Fc starts at Ala 40. The calculated
Data Sheet - N8911
molecule
is synthesized as a 2318 amino acid precursor that
contains a 39 amino acid signal sequence, a 1603
amino acid extracellular region, a 20 amino acid
transmembrane segment, and a 655 amino acid
cytoplasmic
Cellutions Newsletter: 2007, Volume 1
differentiation. Blood 106:1601-1603.
references
± Sem from both endosteal
and central marrow HSC
isolated from 15 animals and
transplanted into 3
individual recipients. Sorted
Novabiochem®Guide to selection of building blocks
et al. (1988) J. Biol. Chem., 263, 1719.
13. S. R. Chhabra, et al. (1998) Tetrahedron Lett., 39, 1603.
1 http://scholar.google.co.uk/scholar?cites=7545760316968945982.; http://scholar.google.co.uk/scho