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Showing 1-30 of 253 results for "16033" within Papers
Milena K Bulla et al.
Photochemistry and photobiology, 91(3), 558-566 (2015-01-13)
Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to
Ning Li et al.
Wei sheng yan jiu = Journal of hygiene research, 32(4), 349-352 (2003-10-11)
Toxicological effect of 3-chloro-1,2-propanediol on rats were studied to provide scientific basis for assessing the effect of Chloropropanols on human health. 170 SD rats were divided randomly into 8 groups and the dose of 0, 0.25, 0.5, 1.0, 2.0, 4.0
Woan-Ruoh Lee et al.
Journal of pharmaceutical sciences, 103(11), 3542-3552 (2014-09-05)
Alopecia usually cannot be cured because of the available drug therapy being unsatisfactory. To improve the efficiency of treatment, erbium-yttrium-aluminum-garnet (Er-YAG) laser treatment was conducted to facilitate skin permeation of antialopecia drugs such as minoxidil (MXD), diphencyprone (DPCP), and peptide.
Hua Zhang et al.
Biomaterials, 56, 104-113 (2015-05-03)
Ultrasound molecular imaging has great potential to impact early disease diagnosis, evaluation of disease progression and the development of target-specific therapy. In this paper, two neuropilin-1 (NRP) targeted peptides, CRPPR and ATWLPPR, were conjugated onto the surface of lipid microbubbles
J Megan Gray et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(9), 3879-3892 (2015-03-06)
Corticotropin-releasing hormone (CRH) is a central integrator in the brain of endocrine and behavioral stress responses, whereas activation of the endocannabinoid CB1 receptor suppresses these responses. Although these systems regulate overlapping functions, few studies have investigated whether these systems interact.
Dominik Bogen et al.
Oncotarget, 6(34), 35247-35262 (2015-10-27)
Despite advances in multimodal treatment, neuroblastoma (NB) is often fatal for children with high-risk disease and many survivors need to cope with long-term side effects from high-dose chemotherapy and radiation. To identify new therapeutic targets, we performed an siRNA screen
Yasaman Damestani et al.
Lasers in surgery and medicine, 46(6), 488-498 (2014-05-28)
Optical clearing agents (OCAs) have shown promise for increasing the penetration depth of biomedical lasers by temporarily decreasing optical scattering within the skin. However, their translation to the clinic has been constrained by lack of practical means for effectively perfusing
Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
Fengjiao Zhou et al.
Journal of bioscience and bioengineering, 120(1), 9-16 (2014-12-31)
Several carbonaceous mesocellular foams (C-MCFs) were prepared with MCF-silica as template using the carbon precursors of sucrose, furfuryl alcohol and lab-made phenolic resin, and the corresponding C-MCFs were named as C-MCF-Suc, C-MCF-FA and C-MCF-PR, respectively. The results of SEM, transmission
Benjawan Boonkaew et al.
Burns : journal of the International Society for Burn Injuries, 40(8), 1562-1569 (2014-04-29)
A novel burn wound hydrogel dressing has been previously developed which is composed of 2-acrylamido-2-methylpropane sulfonic acid sodium salt with silver nanoparticles (silver AMPS). This study compared the cytotoxicity of this dressing to the commercially available silver products; Acticoat™, PolyMem
Y Yoshida
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 60(2), 183-194 (1985-03-01)
Methionine is a sulfur-containing essential amino acid and there are optic isomers of L- and D-type. It has been known that there are two metabolic pathways in methionine metabolism-the transsulfuration and the transamination. The purposes of the present investigation are
Mutlaq M Al-Subaie et al.
International journal of nanomedicine, 10, 3973-3985 (2015-06-26)
This study aimed to formulate an optimized acyclovir (ACV) nanoemulsion hydrogel in order to provide a solution for the slow, variable, and incomplete oral drug absorption in patient suffering from herpes simplex viral infection. Solubility of ACV in different oils
Hae-Kyoung Lim et al.
The aging male : the official journal of the International Society for the Study of the Aging Male, 18(2), 124-132 (2014-08-20)
A substantial proportion of men with prostatic disease have an increased risk of bone loss. In the present study, we investigated the effects of Rubus coreanus Miquel (RCM) extracts on osteoporosis that occurs with N-methyl-N-nitrosourea (MNU)-induced prostatic hyperplasia. The rats
Jianli Wang et al.
Human brain mapping, 35(8), 3616-3624 (2013-12-05)
Human olfactory system is under-studied using fMRI compared with other sensory systems. Because the perception (intensity, threshold, and valence) and detection of odors are tightly involved with respiration, the subject's respiration pattern modulates and interacts with the experimental paradigm, which
Carla Caddeo et al.
International journal of pharmaceutics, 443(1-2), 128-136 (2013-01-10)
Diclofenac-loaded phospholipid vesicles, namely conventional liposomes, ethosomes and PEVs (penetration enhancer-containing vesicles) were developed and their efficacy in TPA (phorbol ester) induced skin inflammation was examined. Vesicles were made from a cheap and unpurified mixture of phospholipids and diclofenac sodium;
Bin Duan et al.
Tissue engineering. Part C, Methods, 21(8), 795-807 (2015-01-17)
Living tissue-engineered heart valves (TEHV) would be a major benefit for children who require a replacement with the capacity for growth and biological integration. A persistent challenge for TEHV is accessible human cell source(s) that can mimic native valve cell
Xiao-Sheng Tian et al.
CNS neuroscience & therapeutics, 21(5), 398-409 (2015-01-23)
This study explored whether surgical stress-induced glucocorticoid receptor (GR) phosphorylation is related to postoperative cognitive dysfunction (POCD) in aged individuals. Inhibition of GR activation could be an effective treatment for POCD. A laparotomy was given to C57/BL6 mice in POCD
Beatriz Clares et al.
International journal of pharmaceutics, 473(1-2), 591-598 (2014-08-08)
The aim of this study was to develop biocompatible lipid-based nanocarriers for retinyl palmitate (RP) to improve its skin delivery, photostability and biocompatibility, and to avoid undesirable topical side effects. RP loaded nanoemulsions (NEs), liposomes (LPs) and solid lipid nanoparticles
Khaled Mohamed Hosny et al.
International journal of pharmaceutics, 475(1-2), 191-197 (2014-09-03)
Saquinavir mesylate (SM) is a protease inhibitor with activity against human immunodeficiency virus type 1 (HIV-1) and is available in tablet form, which has three major problems. First, the drug undergoes extensive first pass metabolism. Second, the drug has a
J S LaKind et al.
Critical reviews in toxicology, 29(4), 331-365 (1999-08-18)
The purpose of this article is to review and interpret the scientific literature on the mammalian toxicity of ethylene glycol (EG) and propylene glycol (PG), with the goal of comparing the toxicity of the two chemicals. This type of review
Luciana Pinato et al.
Brain structure & function, 220(2), 827-840 (2013-12-24)
Although melatonin is mainly produced by the pineal gland, an increasing number of extra-pineal sites of melatonin synthesis have been described. We previously demonstrated the existence of bidirectional communication between the pineal gland and the immune system that drives a
Stephen T Vito et al.
Toxicology and applied pharmacology, 281(2), 185-194 (2014-12-03)
Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison for which there is currently no approved antidote. The convulsant action of TETS is thought to be mediated by inhibition of type A gamma-aminobutyric acid receptor (GABAAR) function. We, therefore, investigated the effects
C Hahn et al.
Journal of lipid research, 36(9), 2059-2066 (1995-09-01)
The serum concentration of 7 alpha-hydroxycholesterol as an indicator of total bile acid synthesis was investigated under different experimental conditions in humans. 7 alpha-Hydroxycholesterol was measured by gas-liquid chromatography-mass spectrometry, using [2H7]7 alpha-hydroxycholesterol and/or 5 alpha-cholestane-3 beta, 6 beta-diol as
Simultaneous determination of plasma phenethylamine, phenylethanolamine, tyramine and octopamine by high-performance liquid chromatography using derivatization with fluorescamine.
T Yonekura et al.
Journal of chromatography, 427(2), 320-325 (1988-06-03)
Kenneth B Sloan et al.
Journal of cosmetic science, 64(3), 181-192 (2013-06-12)
It would be useful to develop a surrogate for animal skin, which could be use to predict flux through human skin. The fluxes (and physicochemical properties) of sunscreens and other compounds from propylene glycol (PG):water (AQ), 30:70, through human skin
Justin D Delorit et al.
Water environment research : a research publication of the Water Environment Federation, 86(4), 366-371 (2014-05-24)
Aircraft deicing fluid used at airport facilities is often collected for treatment or disposal in order to prevent serious ecological threats to nearby surface waters. This study investigated lab scale degradation of propylene glycol, the active ingredient in a common
Adriana Machado-Lima et al.
Journal of cellular physiology, 230(6), 1250-1257 (2014-11-22)
Advanced glycation end products (AGE) are elevated in diabetes mellitus (DM) and predict the development of atherosclerosis. AGE-albumin induces oxidative stress, which is linked to a reduction in ABCA-1 and cholesterol efflux. We characterized the glycation level of human serum
Nicola Parisi et al.
International journal of pharmaceutics, 493(1-2), 404-411 (2015-08-04)
Hexamidine diisethionate (HEX D) has been used in the personal care industry and in a number of over-the-counter (OTC) drug products as an antimicrobial agent since the 1950's. Recently, the compound has also been investigated for its beneficial effects on
Zak E Hughes et al.
The journal of physical chemistry. B, 117(12), 3362-3375 (2013-03-01)
Polyhydroxylated alcohols and DMSO are common cryosolvents that can damage cell membranes at sufficiently high concentrations. The interaction of representative plant cell membranes composed of mixed 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)-β-sitosterol bilayers, at a range of compositions, with a variety of cryosolvent molecules
G G Gancevici
Roumanian archives of microbiology and immunology, 52(4), 293-303 (1993-10-01)
A complement-inhibiting formulation with anti-inflammatory activity due to suppression of both the classical and alternative pathways of complement activation is presented for local treatment of muco-cutaneous lesions produced by Herpes simplex virus, types 1 and 2. The drug contains glutaraldehyde
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