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Showing 1-30 of 78 results for "1609002" within Papers
Raimo A Ketola et al.
Forensic science international, 249, e7-11 (2015-02-17)
Kavalactones are a group of compounds found in kava, a beverage or extract prepared from the rhizome of the kava plant (Piper methysticum). Traditionally kava extracts have been used for their anxiolytic and sedative properties. Sales of kava extracts were
Mariana Rivas-San Vicente et al.
Journal of experimental botany, 62(10), 3321-3338 (2011-03-02)
In recent years salicylic acid (SA) has been the focus of intensive research due to its function as an endogenous signal mediating local and systemic plant defence responses against pathogens. It has also been found that SA plays a role
Armagan Kaya et al.
Ecotoxicology and environmental safety, 106, 232-238 (2014-05-27)
In this study, we comparatively evaluated the effects of the flurochloridone as well as flurochloridone and exogenously applied salicylic acid (SA) on Helianthus annuus L. to find out herbicide-induced toxicity reducing influence of SA. We examined and compared the physiological
Jian-Zhong Liu et al.
Molecular plant-microbe interactions : MPMI, 27(8), 824-834 (2014-04-26)
It has been well established that MPK6 is a positive regulator of defense responses in model plants such as Arabidopsis and tobacco. However, the functional importance of soybean MPK6 in disease resistance has not been investigated. Here, we showed that
Sébastien Anthérieu et al.
Toxicology and applied pharmacology, 276(1), 63-72 (2014-02-15)
Drinking water can be contaminated with pharmaceuticals. However, it is uncertain whether this contamination can be harmful for the liver, especially during obesity. Hence, the goal of our study was to determine whether chronic exposure to low doses of pharmaceuticals
Jon Lucas Boatwright et al.
Molecular plant pathology, 14(6), 623-634 (2013-04-30)
Salicylic acid (SA) acts as a signalling molecule in plant defence against biotrophic and hemibiotrophic phytopathogens. The biosynthesis of SA on pathogen detection is essential for local and systemic acquired resistance, as well as the accumulation of pathogenesis-related (PR) proteins.
Bokun Lin et al.
Journal of hazardous materials, 282, 158-164 (2014-07-30)
Pharmaceuticals have recently been regarded as contaminants of emerging concern. To date, there is limited knowledge about antibiotic-degrading microorganisms in conventional activated sludge treatment systems and their characteristics toward antibiotic degradation especially in the presence of a pharmaceutical mixture. As
Jyoti Shah
Current opinion in plant biology, 6(4), 365-371 (2003-07-23)
Salicylic acid is an important signal molecule in plant defense. In the past two years, significant progress has been made in understanding the mechanism of salicylic-acid biosynthesis and signaling in plants. A pathway similar to that found in some bacteria
Mahesh P Paudyal et al.
Bioorganic & medicinal chemistry, 22(24), 6781-6788 (2014-12-04)
Previously, we identified a class of salicylic acid derivatives that display inhibitory activity against the protein tyrosine phosphatase YopH from Yersinia pestis. Because docking study suggested that the large phenyl ring attaching to the salicylic acid core might be exposed
Sang-Keun Oh et al.
FEBS letters, 588(7), 1109-1115 (2014-03-04)
The Rpi-blb2 recognizes the presence of the Phytophthora infestans AVRblb2 and initiates effector-triggered immunity (ETI). We performed gain-of-function and loss-of-function studies in Nicotiana benthamiana to elucidate Rpi-blb2-mediated resistance to P. infestans. Rpi-blb2 triggered a hypersensitive response through SGT1-mediated, but not
Salicylic acid-, jasmonic acid- and ethylene-mediated regulation of plant defense signaling.
Aardra Kachroo et al.
Genetic engineering, 28, 55-83 (2006-12-13)
Hua Lu
Plant signaling & behavior, 4(8), 713-717 (2009-10-13)
The small phenolic molecule salicylic acid (SA) plays a key role in plant defense. Significant progress has been made recently in understanding SA-mediated defense signaling networks. Functional analysis of a large number of genes involved in SA biosynthesis and regulation
Chongming Liu et al.
Journal of mass spectrometry : JMS, 49(8), 692-699 (2014-07-22)
On contrary to the widely accepted conviction that the m/z 93 ion derived from phenol does not react with CO2, we demonstrate that it makes an adduct with CO2 to a small but demonstrable extent. For example, the product-ion mass
Lijuan Su et al.
Rapid communications in mass spectrometry : RCM, 28(11), 1265-1272 (2014-04-25)
Monitoring the concentrations of pharmaceuticals and personal care products (PPCPs) in wastewater is an integral step toward understanding the fate of these contaminants in wastewater treatment plants (WWTPs). This paper aims to develop a method that allows for the simultaneous
Faqir Muhammad et al.
International journal of pharmaceutics, 483(1-2), 151-157 (2015-02-15)
Many natural products have the potential to modulate the dermal penetration of topically applied drugs and chemicals. We studied the effect of five natural compounds (hydroxycitronellal, limonene 1,2-epoxide, terpinyl acetate, p-coumaric acid, transferrulic acid) and ethanol on the transdermal penetration
Zhixiang Chen et al.
Plant signaling & behavior, 4(6), 493-496 (2009-10-10)
Salicylic acid (SA) is an important signal molecule in plants. Two pathways of SA biosynthesis have been proposed in plants. Biochemical studies using isotope feeding have suggested that plants synthesize SA from cinnamate produced by the activity of phenylalanine ammonia
Laura Campos et al.
Molecular plant-microbe interactions : MPMI, 27(10), 1159-1169 (2014-07-12)
Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, antiviral, antibacterial, and antifungal activities. Hydroxycinnamoyl-CoA:tyramine N-hydroxycinnamoyl transferase (THT) is the key enzyme in
Andrea Clavijo McCormick et al.
Plant, cell & environment, 37(8), 1909-1923 (2014-01-30)
After herbivory, plants release volatile organic compounds from damaged foliage as well as from nearby undamaged leaves that attract herbivore enemies. Little is known about what controls the volatile emission differences between damaged and undamaged tissues and how these affect
Yogita Bansal et al.
Archives of pharmacal research, 37(11), 1426-1436 (2013-11-06)
Polyfunctional compounds comprise a novel class of therapeutic agents for treatment of multifactorial diseases. The present study reports a series of benzimidazole-non-steroidal anti-inflammatory drugs (NSAIDs) conjugates (1-10) as novel polyfunctional compounds synthesized in the presence of orthophosphoric acid. The compounds
Gary Loake et al.
Current opinion in plant biology, 10(5), 466-472 (2007-10-02)
Salicylic acid (SA) is synthesised by plants in response to challenge by a diverse range of phytopathogens and is essential to the establishment of both local and systemic-acquired resistance (SAR). SA application induces accumulation of pathogenesis-related (PR) proteins. Mutations leading
Nadine Strehmel et al.
Phytochemistry, 108, 35-46 (2014-12-03)
To explore the chemical composition of root exudates of the model plant Arabidopsis thaliana a workflow for nontargeted metabolite profiling of the semipolar fraction of root exudates was developed. It comprises hydroponic plant cultivation and sampling of root exudates under
María Ramos-Payán et al.
Analytica chimica acta, 849, 7-11 (2014-10-11)
A novel approach based on the use of nanometallic-decorated hollow fibers to assist electromembrane extraction is proposed. Microporous polypropylene hollow fibers, on which nanometallic silver was deposited, have been used for the first time as liquid membrane support in electromembrane
Tomohisa Horibe et al.
Chembiochem : a European journal of chemical biology, 15(11), 1599-1606 (2014-06-13)
In order to regulate the activity of P5, which is a member of the protein disulfide isomerase family, we screened a chemical compound library for P5-specific inhibitors, and identified two candidate compounds (anacardic acid and NSC74859). Interestingly, anacardic acid inhibited
Oussama Ahrazem et al.
Plant science : an international journal of experimental plant biology, 234, 60-73 (2015-03-26)
Glycosyltransferases play diverse roles in cellular metabolism by modifying the activities of regulatory metabolites. Three stress-regulated UDP-glucosyltransferase-encoding genes have been isolated from the stigmas of saffron, UGT85U1, UGT85U2 and UGT85V1, which belong to the UGT85 family that includes members associated
Mike De Vrieze et al.
Analytical and bioanalytical chemistry, 406(25), 6179-6188 (2014-08-16)
Over the past decades, several in vitro methods have been tested for their ability to predict drug penetration across the blood-brain barrier. So far, in high-performance liquid chromatography, most attention has been paid to micellar liquid chromatography and immobilized artificial
Chad D Iverson et al.
Journal of chromatography. A, 1373, 17-24 (2014-12-04)
Most stationary phases for hydrophilic interaction liquid chromatography (HILIC) and reversed phase liquid chromatography (RPLC) are based on silica. Porous graphitic carbon (PGC) is an attractive alternative to silica-based phases due to its chemical and thermal stability, and unique selectivity.
Osamu Kimura et al.
Biological & pharmaceutical bulletin, 37(9), 1475-1479 (2014-09-02)
The uptake mechanism of aristolochic acid I (AAI) was investigated using Caco-2 cells cultured on dishes and permeable membranes. The uptake of AAI from the apical membrane of Caco-2 cells cultured on a dish was rapid, and a decrease in
Julia E Vela-Ramirez et al.
The AAPS journal, 17(1), 256-267 (2014-11-26)
Carbohydrate functionalization of nanoparticles allows for targeting of C-type lectin receptors. This family of pattern recognition receptors expressed on innate immune cells, such as macrophages and dendritic cells, can be used to modulate immune responses. In this work, the in
Caroline Gutjahr et al.
Molecular plant-microbe interactions : MPMI, 22(7), 763-772 (2009-06-16)
Work on the interaction of aerial plant parts with pathogens has identified the signaling molecules jasmonic acid (JA) and salicylic acid (SA) as important players in induced defense of the plant against invading organisms. Much less is known about the
Raman K Madan et al.
Journal of the American Academy of Dermatology, 70(4), 788-792 (2014-01-30)
Topical salicylic acid is often used in dermatologic conditions because of its keratolytic, bacteriostatic, fungicidal, and photoprotective properties. The bioavailability of salicylic acid differs depending on the vehicle used and pH of transcellular fluids. Although rare, salicylic acid toxicity (salicylism)
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