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Showing 1-30 of 490 results for "168149" within Papers
Xiaodong Zhang et al.
Journal of colloid and interface science, 455, 6-15 (2015-06-06)
The problem of stability hinders the practical applications of nanomaterials. In this research, an innovative and simple synthetic method was developed for preparing ultrastable and multifunctional gold nanoclusters (Au NCs). HS-C11-EG6-X is a class of molecules consisting of four components:
Shuichi Ohnishi et al.
Biochemistry, 53(14), 2261-2270 (2014-03-29)
Organic anion transporting polypeptide (OATP) 1B1 is an important drug transporter expressed in human hepatocytes. Previous studies have indicated that transmembrane (TM) domain 2, 6, 8, 9, and in particular 10 might be part of the substrate binding site/translocation pathway.
Kaveri Sidhu et al.
Biochemistry, 53(28), 4685-4695 (2014-06-28)
Many proteins rely on disulfide bonds formed between pairs of cysteines for the stability of their folded state and to keep regulatory control over their functions. The hepatitis B virus-encoded HBx oncoprotein is known to perform an overwhelming array of
Hadi Hassani Nadiki et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 30(9), 911-918 (2014-09-13)
A glassy carbon electrode modified with ruthenium red and functionalized multi-walled carbon nanotube has been developed. The electrochemical response characteristics of the modified electrode toward epinephrine (EP) and acetaminophen (AC) was investigated by differential pulse voltammetry (DPV). Linear calibration plots
Jia-Xuan Qiu et al.
Drug design, development and therapy, 9, 349-417 (2015-01-23)
Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells using the approach
M Ellaurie et al.
The Pediatric infectious disease journal, 11(4), 286-289 (1992-04-01)
Neopterin concentrations in 50 children with human immunodeficiency virus infection were correlated with disease course. The neopterin concentrations ranged from 4 to 70 nM with a mean of 34.7 +/- 25.1 (SD) nM compared with a mean of 6.1 +/-
Daisuke Kurita et al.
Nucleic acids research, 42(21), 13339-13352 (2014-10-31)
Although trans-translation mediated by tmRNA-SmpB has long been known as the sole system to relieve bacterial stalled ribosomes, ArfA has recently been identified as an alternative factor for ribosome rescue in Escherichia coli. This process requires hydrolysis of nascent peptidyl-tRNA
Karen L Andrews et al.
Clinical science (London, England : 1979), 129(2), 179-187 (2015-03-03)
Pre-clinical studies have identified nitroxyl (HNO), the reduced congener of nitric oxide (NO•), as a potent vasodilator which is resistant to tolerance development. The present study explores the efficacy of HNO in human blood vessels and describes, for the first
Yang Hai et al.
Biochemistry, 52(51), 9294-9309 (2013-11-23)
The crystal structure of formiminoglutamase from Trypanosoma cruzi (TcFIGase) is reported at 1.85 Å resolution. Although the structure of this enzyme was previously determined by the Structural Genomics of Pathogenic Protozoa Consortium (PDB accession code 2A0M), this structure was determined
Míriam R García et al.
International journal of food microbiology, 208, 65-74 (2015-06-10)
Fish quality has a direct impact on market price and its accurate assessment and prediction are of main importance to set prices, increase competitiveness, resolve conflicts of interest and prevent food wastage due to conservative product shelf-life estimations. In this
Shiuh-Rong Ho et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2646-E2655 (2014-07-01)
Several ring between ring fingers (RBR) -domain proteins, such as Parkin and Parc, have been shown to be E3 ligases involved in important biological processes. Here, we identify a poorly characterized RBR protein, Ring Finger protein 144A (RNF144A), as the
Gustavo Luis Leonardo Scalone et al.
Journal of agricultural and food chemistry, 63(22), 5364-5372 (2015-05-15)
Pyrazines are specific Maillard reaction compounds known to contribute to the unique aroma of many products. Most studies concerning the generation of pyrazines in the Maillard reaction have focused on amino acids, while little information is available on the impact
Complexes of L-cysteine and D-penicillamine with gold (I) and (III).
D H Brown et al.
Proceedings of the Royal Society of Medicine, 70 Suppl 3, 41-42 (1977-01-01)
Ana C Ebrecht et al.
Biochimica et biophysica acta, 1850(1), 88-96 (2014-10-16)
Giardia lamblia is a pathogen of humans and other vertebrates. The synthesis of glycogen and of structural oligo and polysaccharides critically determine the parasite's capacity for survival and pathogenicity. These characteristics establish that UDP-glucose is a relevant metabolite, as it
Marianne Overgaard Hesselager et al.
Proteomics, 15(13), 2350-2357 (2015-03-15)
The gut epithelium formed between an organism and the environment plays an essential role in host-microbe interactions, yet remains one of the least characterized mammalian tissues. Especially the membrane proteins, which are critical to bacterial adhesion, are understudied, because these
Wenceslaus Luoga et al.
Parasitology, 142(7), 989-998 (2015-03-05)
Eight strains of mice, of contrasting genotypes, infected with Heligmosomoides bakeri were studied to determine whether the anthelmintic efficacy of papaya latex varied between inbred mouse strains and therefore whether there is an underlying genetic influence on the effectiveness of
Carla Foditsch et al.
PloS one, 9(12), e116465-e116465 (2015-01-01)
The goal of our study was to isolate and characterize Faecalibacterium prausnitzii from fecal samples of healthy calves and piglets, in order to develop a novel probiotic for livestock animals. We identified 203 isolates of Faecalibacterium sp., which were clustered
Andrey Galkin et al.
The Journal of biological chemistry, 289(15), 10502-10509 (2014-02-22)
Carbamate kinase from Giardia lamblia is an essential enzyme for the survival of the organism. The enzyme catalyzes the final step in the arginine dihydrolase pathway converting ADP and carbamoyl phosphate to ATP and carbamate. We previously reported that disulfiram
Min Zhang et al.
PloS one, 10(5), e0127386-e0127386 (2015-05-23)
Death signaling provided by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can induce death in cancer cells with little cytotoxicity to normal cells; this cell death has been thought to involve caspase-dependent apoptosis. Reactive oxygen species (ROS) are also mediators
K B Shumaev et al.
Biofizika, 58(2), 239-245 (2013-06-13)
It has been shown that interaction of cysteine dinitrosyl iron complexes with methylglyoxal leads to the formation of a new type of dinitrosyl iron complexes., EPR spectrum of these complexes essentially differs from spectra of dinitrosyl iron complexes containing unmodified
Chun-Ming Chou et al.
Bioorganic & medicinal chemistry, 22(15), 4177-4188 (2014-06-24)
Symplectin is one of the few photoproteins, which forms covalent bonds with the dehydro-coelenterazine (DCL) at the binding sites and the active site. This binding takes place through the SH's of the cysteine residues via conjugate addition reaction. This photoprotein
Md Nurul Islam et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 55-62 (2014-04-10)
Vicenin 2, isolated from a traditionally used medicinal plant Artemisia capillaris, is a 6,8-di-C-glucoside of apigenin which has been previously reported to possess a wide variety of pharmacological activities including antioxidant, anti-inflammatory, anti-cancer, and hepatoprotective. However, there have not been
Piero Pingitore et al.
Biochimica et biophysica acta, 1828(9), 2238-2246 (2013-06-13)
The human glutamine/neutral amino acid transporter ASCT2 (hASCT2) was over-expressed in Pichia pastoris and purified by Ni(2+)-chelating and gel filtration chromatography. The purified protein was reconstituted in liposomes by detergent removal with a batch-wise procedure. Time dependent [(3)H]glutamine/glutamine antiport was
Sebastián Carballal et al.
Biochemistry, 52(26), 4553-4562 (2013-06-25)
Cystathionine β-synthase (CBS) catalyzes the condensation of homocysteine with serine or cysteine to form cystathionine and water or hydrogen sulfide (H2S), respectively. In addition to pyridoxal phosphate, human CBS has a heme cofactor with cysteine and histidine as ligands. While
Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKK?.
Heyninck K, Lahtela-Kakkonen M, Van der Veken P, et al.
Biochemical Pharmacology, 91(4), 501-509 (2014)
Li Yuan et al.
Journal of agricultural and food chemistry, 62(23), 5390-5400 (2014-05-21)
Cell death is closely related to autophagy under some circumstances; however, the effect of isoorientin (ISO) on autophagy and the interplay between apoptosis and autophagy in human hepatoblastoma cancer (HepG2) cells remains poorly understood. The present study showed that ISO
M C Martínez-Herrero et al.
Avian pathology : journal of the W.V.P.A, 43(6), 535-546 (2014-09-30)
Oropharyngeal trichomonad isolates of wild birds from Spain were studied. A total of 1688 samples (1214 of predator birds and 474 of prey species) from wildlife recovery centres and scientific bird-ringing campaigns were analysed from 2011 to 2013. The overall
Seon-Mi Yu et al.
Journal of Korean medical science, 29(8), 1042-1053 (2014-08-15)
Withaferin A (WFA) is known as a constituent of Ayurvedic medicinal plant, Withania somnifera, and has been used for thousands of years. Although WFA has been used for the treatment of osteoarthritis (OA) and has a wide range of biochemical
Rima Obeid et al.
Clinical chemistry, 53(6), 1129-1136 (2007-03-27)
Increased plasma total homocysteine (tHcy) is a risk factor for neurological diseases, but the underlying pathophysiology has not been adequately explained. We evaluated concentrations of tHcy, S-adenosyl homocysteine (SAH), S-adenosyl methionine (SAM), folate, and vitamin B(12) in cerebrospinal fluid (CSF)
L G Darlington et al.
The European journal of neuroscience, 26(8), 2211-2221 (2007-09-26)
Inflammation and oxidative stress are involved in brain damage following stroke, and tryptophan oxidation along the kynurenine pathway contributes to the modulation of oxidative stress partly via the glutamate receptor agonist quinolinic acid and antagonist kynurenic acid, and via redox-active
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