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Showing 1-30 of 32 results for "169102" within Papers
Nahed Abdel-Haq et al.
Indian journal of pediatrics, 73(4), 313-321 (2006-07-04)
During the last three decades, a better understanding of viral replication and disease states caused by viral infections have led to the development of newer antiviral agents with enhanced activity and better tolerability. This review focuses on newer systemic and
Prescrire international, 18(101), 106-107 (2009-07-30)
(1) Herpes is a contagious, recurrent viral infection of the skin and mucous membranes. In immunocompetent patients the recurrences can be troublesome but they heal spontaneously. Management is mainly based on lifestyle measures. Local application of an antiviral drug such
John J Docherty et al.
Antiviral research, 61(1), 19-26 (2003-12-13)
Resveratrol (3,5,4'-trihydroxystilbene) is a natural component of certain foods, such as grapes, that has been shown to have anti-herpes simplex virus (HSV) activity in vitro. To determine if it is active in vivo, the abraded epidermis of SKH1 mice were
Synthesis and self-assembly of amphiphilic dendrimers based on aliphatic polyether-type dendritic cores.
Cho B-K, et al.
Macromolecules, 37(11), 4227-4234 (2004)
Comments on study of paw pad lesions in dogs.
Emily J Walder et al.
Journal of the American Veterinary Medical Association, 235(6), 657-658 (2009-09-16)
Luciana María Cocchiararo-Bastias et al.
Journal of chemical ecology, 37(3), 246-252 (2011-03-05)
Epicuticular lipids are contact cues in intraspecific chemical communication in insects, both for aggregation and sexual behavior. Triatomine bugs are vectors of the parasite Trypanosoma cruzi, the cause of Chagas disease. In Triatoma infestans, the major epicuticular lipids are hydrocarbons
Daniel T Leung et al.
Expert opinion on pharmacotherapy, 5(12), 2567-2571 (2004-12-02)
Recurrent herpes labialis is a painful and potentially disfiguring infection affecting an estimated 40 million people in the US alone. The majority of recurrences are caused by herpes simplex virus type 1. Various oral and topical formulations of nucleoside analogues
New drug approvals in 2000.
R L Wynn
General dentistry, 49(4), 341-345 (2002-05-23)
Xiuli Yue et al.
The journal of physical chemistry. B, 110(44), 22237-22244 (2006-11-03)
A systematic analysis of pressure-area isotherms and grazing incidence X-ray diffraction (GIXD) data of 22-methoxydocosan-1-ol (H3C-O-(CH2)22-OH, MDO), docosan-1-ol (H3C-(CH2)21-OH, DO), and docosyl methyl ether (H3C-(CH2)21-O-CH3, DME) monolayers on pure water between 10 and 35 degrees C is presented. All monolayers
Nathaniel S Treister et al.
Expert opinion on pharmacotherapy, 11(5), 853-860 (2010-03-10)
Recurrent herpes labialis (RHL) is a significant disorder with social and health consequences that affects upwards of 20 - 40% of the adult population. Docosanol is the only FDA-approved topical agent that is available over the counter for management of
D H Katz et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10825-10829 (1991-12-01)
This article reports that 1-docosanol, a 22-carbon-long saturated alcohol, exerts a substantial inhibitory effect on replication of certain viruses (e.g., herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. To study the basis for its viral
Marcin Broniatowski et al.
The journal of physical chemistry. B, 110(7), 3078-3087 (2006-02-24)
This work presents the results of phase behavior studies of two-dimensional (2D) binary systems involving semifluorinated alkanes (SFAs) and fatty alcohols. Four different SFAs were selected for investigations: (i) with a short and branched perfluorinated moiety (iF3H20), (ii) with a
Guadalupe Iglesias et al.
Regulatory toxicology and pharmacology : RTP, 36(1), 69-79 (2002-10-18)
The genotoxic potential of behenyl alcohol, a saturated long-chain (C22:0) fatty alcohol, was examined in the Ames Salmonella typhimurium reverse mutation assay, the gene mutation, and chromosome aberrations assays in Chinese hamster V79 cells, and the micronucleus assay in NMRI
Commentary. Treatment of herpes labialis: comparison of two OTC drugs and untreated controls.
Peter L Jacobsen
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 24(2), 110-111 (2012-04-25)
[Docosanol (Erazaban), dermal use].
Journal de pharmacie de Belgique, (2)(2), 53-54 (2011-08-10)
Diogo C Morelli et al.
Journal of chromatography. A, 1626, 461377-461377 (2020-08-17)
This study reports the use ofa natural deep eutectic solvent (NADES) with hollow fiber-microporous membrane liquid-liquid microextraction (HF-MMLLE) for the multiclass determination of 11 compounds classified as emerging contaminantsin water. Different deep eutectic solvents were synthetized and Thymol: Camphor (1:1
Shih-Hung Lin et al.
Drug design, development and therapy, 9, 3313-3324 (2015-07-15)
Cholesterol plays an important role in living cells. However, a very high level of cholesterol may lead to atherosclerosis. HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase is the key enzyme in the cholesterol biosynthesis pathway, and the statin-like drugs are inhibitors of
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
James P McCarthy et al.
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 24(2), 103-109 (2012-04-25)
Rapid resolution of active herpes labialis lesions is of great benefit to the patient not only in terms of controlling pain and disfigurement, but in disruption of needed dental treatment. Using three groups, this retrospective study investigated the time required
Efficacy of docosanol.
Stephen L Sacks
Journal of the American Academy of Dermatology, 49(3), 558-559 (2003-09-10)
Guadalupe Iglesias et al.
Regulatory toxicology and pharmacology : RTP, 36(1), 80-85 (2002-10-18)
Behenyl alcohol is a saturated 22-carbon, long-chain aliphatic alcohol, which has potential for use in foods as an oil-structuring and -solidifying agent in fats. Previously completed studies with behenyl alcohol indicated an absence of mutagenic or genotoxic potential. In addition
Caroline A C Kadu et al.
Phytochemistry, 83, 70-78 (2012-07-17)
Prunus africana--an evergreen tree found in Afromontane forests--is used in traditional medicine to cure benign prostate hyperplasia. Different bioactive constituents derived from bark extracts from 20 tree populations sampled throughout the species' natural range in Africa were studied by means
N-docosanol (Abreva) for herpes labialis: problems and questions.
Spotswood L Spruance
Journal of the American Academy of Dermatology, 47(3), 457-458 (2002-08-28)
Ai-Mei Yang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1534-1537 (2010-02-02)
To study the chemical constituents from Clematis brevicaudata. The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis (NMR). Eight compounds were isolated and identified as: palmitic acid (1), 1-docosanol (2), pentacosanoic acid-2', 3'-dihydroxypropyl ester
Pipsa Kulovesi et al.
Investigative ophthalmology & visual science, 55(7), 4448-4454 (2014-05-31)
The tear film lipid layer is believed to stabilize the tear film and to retard evaporation. Based on previous simple in vitro studies, the evidence for the latter property is scarce. In this study, we used complex lipid mixtures including
Clara L Shaw et al.
Journal of chemical ecology, 37(4), 329-339 (2011-03-23)
The uropygial secretions of some bird species contain volatile and semivolatile compounds that are hypothesized to serve as chemical signals. The abundance of secretion components varies with age and season, although these effects have not been investigated in many species.
Therapeutic options for herpes labialis, II: Topical agents.
Diana Elish et al.
Cutis, 74(1), 35-40 (2004-08-06)
A review of antiviral therapy for herpes labialis.
M Vander Straten et al.
Archives of dermatology, 137(9), 1232-1235 (2001-09-18)
John F Marcelletti
Antiviral research, 56(2), 153-166 (2002-10-09)
Interactions between docosanol (n-docosanol, behenyl alcohol) and nucleoside or pyrophosphate analogs were investigated in vitro. The anti-HSV activity of acyclovir (ACV) was synergistically enhanced by treatment of cells with docosanol as judged by inhibition of progeny virus production and plaque
Jean Pierre Raynaud et al.
The Journal of steroid biochemistry and molecular biology, 82(2-3), 233-239 (2002-12-13)
In different cell systems, the lipido-sterolic extract of Serenoa repens (LSESr, Permixon inhibits both type 1 and type 2 5alpha-reductase activity (5alphaR1 and 5alphaR2). LSESr is mainly constituted of fatty acids (90+/-5%) essentially as free fatty acids (80%). Among these
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