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Showing 1-30 of 146 results for "17779" within Papers
Jun Cheng et al.
Food chemistry, 168, 90-99 (2014-08-31)
The aim of this study was to investigate the applicability of artificial neural network (ANN) and multiple linear regression (MLR) models for the estimation of acrylamide reduction by flavonoids, using multiple antioxidant capacities of Maillard reaction products as variables via
Linfeng Qian et al.
Aging, 11(15), 5368-5388 (2019-08-14)
This study is intended to figure out the function of microRNA-218 (miR-218) together with microphthalmia-associated transcription factor (MITF) on the cardiac fibrosis and cardiac function impairment in rat models of myocardial infarction (MI). The rats with MI exhibited cardiac function
Aseesh Pandey et al.
Molecular biology reports, 46(2), 2231-2241 (2019-02-14)
Efficient micropropagation procedure was developed for Origanum vulgare, a high-value culinary herb, and the phytochemicals, phenolic content, antioxidant and antimutagenic activity of leaf and stem, derived from different growing stages were analyzed. The agar solidified Murashige and Skoog (MS) medium
Yao Tang et al.
Food chemistry, 174, 502-508 (2014-12-23)
Composition of fatty acids, tocopherols, tocotrienols, and carotenoids, and their contribution to antioxidant activities were investigated in seeds of three coloured quinoa cultivars (white, red and black). The major components and individual compounds were significantly different, and their concentrations were
John Thundyil et al.
PloS one, 8(1), e53528-e53528 (2013-01-12)
Ephrin (Eph) signaling within the central nervous system is known to modulate axon guidance, synaptic plasticity, and to promote long-term potentiation. We investigated the potential involvement of EphA2 receptors in ischemic stroke-induced brain inflammation in a mouse model of focal
Junyi Shen et al.
Artificial cells, nanomedicine, and biotechnology, 47(1), 192-200 (2019-01-22)
After cerebral infarction, the regeneration of microvascular played an important role in the recovery. Ginsenoside Rg1 (Rg1) had good effects on promoting angiogenesis and neuro-protection in cerebral infarction treatment. However, the blood-brain barrier (BBB) restricted Rg1 to enter into cerebral
Na Zhu et al.
Frontiers in pharmacology, 11, 367-367 (2020-04-16)
Berberine (BBR) has a variety of pharmacological activities and is widely used in Asian countries. However, the clinical application of BBR still lacks scientific basis, what protective mechanism of BBR against myocardial ischemia-reperfusion injury (MIRI). In vitro experiments, BBR pretreatment
Jin-Min Guo et al.
Cell research, 23(7), 915-930 (2013-05-22)
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that metabolizes ethanol and toxic aldehydes such as 4-hydroxy-2-nonenal (4-HNE). Using an unbiased proteomic search, we identified ALDH2 deficiency in stroke-prone spontaneously hypertensive rats (SHR-SP) as compared with spontaneously hypertensive rats (SHR).
Wan-Ting Hung et al.
The European journal of neuroscience, 52(12), 4890-4907 (2020-07-09)
The cellular and molecular mechanisms underlying leptin-mediated brain protection against cerebral ischemia were investigated at the blood-brain barrier (BBB) and neutrophil level. Through the ischemia/reperfusion (I/R) animal model, we found that leptin expression level was significantly decreased in ischemic hemisphere.
Victor Garcia-Bustos et al.
PloS one, 14(2), e0212096-e0212096 (2019-02-12)
Purkinje cells (PCs) are more resistant to ischemia than myocardial cells, and are suspected to participate in ventricular arrhythmias following myocardial infarction (MI). Histological studies afford little evidence on the behavior and adaptation of PCs in the different stages of
Xueming Cao et al.
Journal of cellular physiology, 235(11), 8187-8198 (2020-01-23)
Cardiomyocyte apoptosis induced by hypoxia and ischemia plays important roles in heart dysfunction after acute myocardial infarction (AMI). However, the mechanism of apoptosis induction remains unclear. A previous study reported that Y-box protein 1 (YB1) is upregulated after myocardial hypoxia/reoxygenation
Yi Li et al.
Pharmacological research, 130, 110-122 (2018-02-07)
Mitochondrial reactive oxygen species (mtROS) directly stimulate the inflammatory cytokines cascades and participate in age-related changes of cardiovascular diseases. Application of small molecule targeting the mtROS is significant towards development of better therapy to combat inflammatory response after myocardial infarction
Silvia Ruiz-Crespo et al.
Metabolic brain disease, 28(1), 21-24 (2012-11-20)
Biochemical and metabolic analysis of ischemic cerebral tissue is central in stroke investigation and is usually performed in animal stroke models, such as the permanent occlusion of the middle cerebral artery (MCAO) in the rat that we have used. To
Ratchanee Kongkachuichai et al.
Food chemistry, 173, 838-846 (2014-12-04)
Evidence from epidemiological studies has strongly suggested that diets rich in fruits and vegetables play a vital role in disease prevention. The aim of this study was to determine nutrient and antioxidant content for 15 varieties of indigenous vegetables and
Li Li et al.
Experimental neurology, 234(1), 181-190 (2012-01-10)
Transmembrane protein 166 (TMEM166) is a lysosomal/endoplasmic reticulum-associated protein found in various species where it acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. In the present study, we investigated the role of TMEM166 following MCAO
Jingjing Lu et al.
Life sciences, 260, 118305-118305 (2020-08-23)
The study aims to investigate the roles of LncRNA and miRNA in ferroptosis in brain ischemia/reperfusion (I/R) in vivo and in vitro. qPCR assay was used to analyze lncRNA PVT1 and miR-214 expressions in acute ischemic stroke (AIS) patients. Then
Suning Ping et al.
Aging and disease, 12(1), 72-92 (2021-02-04)
Chemokine (C-C motif) receptor 5 (CCR5) is expressed not only in the immune cells but also in cerebral cells such as neurons, glia, and vascular cells. Stroke triggers high expression of CCR5 in the brain. However, the role of CCR5
Jie Xing et al.
Journal of cellular biochemistry, 120(6), 10145-10154 (2018-12-15)
The aim of this study is to evaluate the effects of microRNA-183 (miRNA-183) in myocardial damager. In the cell experiment, the H9C2 cell was divided into three groups: NC group, Model group, and miRNA group. The cell apoptosis and relative
Sidharth Razdan et al.
Scientific reports, 9(1), 8867-8867 (2019-06-22)
The presence of endotoxin, also known as lipopolysaccharides (LPS), as a side product appears to be a major drawback for the production of certain biomolecules that are essential for research, pharmaceutical, and industrial applications. In the biotechnology industry, gram-negative bacteria
Anjing Zhang et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 39(5), 613-618 (2012-08-31)
The current study explored the effects of treadmill exercise intensity on functional recovery and hippocampal phospho-NR2B (p-NR2B) expression in cerebral ischemic rats, induced by permanent middle cerebral artery occlusion (MCAO) surgery. Adult male Sprague-Dawley rats were randomly divided into four
Gehan H Heeba et al.
Life sciences, 90(11-12), 388-395 (2012-01-10)
Oxidative stress-induced cell damage is reported to contribute to the pathogenesis of cerebral ischemia/reperfusion injury. This study investigated the neuroprotective effect of nebivolol against cerebral ischemia/reperfusion insult in rats. The model adopted was that of surgically-induced forebrain ischemia, performed by
Sunan Wang et al.
Journal of medicinal food, 18(3), 345-353 (2014-10-15)
Previous works on staghorn sumac (Rhus hirta) were mostly dedicated to its phytochemical profiles, antioxidant properties, and antidiabetic potentials. This study explored the potential of staghorn-sumac-derived functional ingredients for food and pharmacological applications. Sumac may have other biological functions, such
Satoshi Ikeda et al.
PloS one, 8(3), e60037-e60037 (2013-03-26)
Rat models of photochemically induced cerebral infarction have been readily studied, but to date there are no reports of transcranial photochemically induced infarctions in the marmoset. In this report, we used this non-human primate as a model of cerebral thrombosis
Jiangcong Hong et al.
International journal of molecular medicine, 31(1), 225-231 (2012-11-07)
Neurogenesis is regulated by a number of signaling pathways, including the retinoic acid (RA) pathway, a key regulator of neurogenesis in the subventricular zone (SVZ) and hippocampus. Acupuncture has been used to treat neurological conditions and is known to potentially
O Kenny et al.
Food chemistry, 161, 79-86 (2014-05-20)
Antimicrobial properties of ethanol and water extracts from eight Asteraceae species were investigated against three Gram positive (Staphylococcus aureus, MRSA and Bacillus cereus) and two Gram negative (Escherichia coli and Salmonella typhimurium) bacterial strains. Ethanol extracts from Centaurea scabiosa, Arctium
Yu-Yo Sun et al.
Journal of neuroscience methods, 203(1), 122-129 (2011-10-11)
A simple method to quantify cerebral infarction has great value for mechanistic and therapeutic studies in experimental stroke research. Immersion staining of unfixed brain slices with 2,3,5-triphenyltetrazolium chloride (TTC) is a popular method to determine cerebral infarction in preclinical studies.
Caroline Pin-Barre et al.
Frontiers in physiology, 9, 638-638 (2018-06-14)
The purpose of the present study was to examine the contribution of group III and IV metabosensitive afferents at spinal and supraspinal levels in rats subjected to middle cerebral artery occlusion (MCAO) with reperfusion during the acute phase. Animals were
Bin Zhou et al.
Journal of molecular neuroscience : MN, 67(3), 400-410 (2019-01-17)
We attempted to explore the possible effects of SOCS3 (suppressor of cytokine signaling 3)-modified bone marrow mesenchymal stem cells (BMSCs) on the hypoxic injury of rat adrenal gland pheochromocytoma (PC-12) cells. PC12 cells were cultured with EGFP (enhanced green fluorescent
Lihong Zhang et al.
Current neurovascular research, 9(3), 167-175 (2012-05-25)
DL-3-n-Butylphthalide (NBP) is a synthetic compound based on L-3-n-Butylphthalide which was isolated from seeds of Apium graveolens. The present study aims at evaluating the outcome of NBP given prior to and after the onset of ischemic stroke in spontaneously hypertensive
Maxime Bafoil et al.
Scientific reports, 9(1), 8649-8649 (2019-06-19)
In order to investigate the effects of low temperature plasmas on germination of Arabidopsis thaliana seeds, a dielectric barrier discharge device generating the plasma in ambient air was used. To highlight the different plasma effects on the seed surface, saline
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