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Showing 1-30 of 46 results for "185892" within Papers
Foyez Mahmud et al.
Molecular pharmaceutics, 12(6), 1911-1920 (2015-04-22)
Currently, oral administration of insulin still remains the best option to avoid the burden of repeated subcutaneous injections and to improve its pharmacokinetics. The objective of the present investigation was to demonstrate the absorption mechanism of insulin in the physical
Y Qiu et al.
Analytica chimica acta, 583(2), 277-283 (2007-03-28)
A new combined gas chromatography and mass spectrometry (GC-MS) method has been developed suitable for the urine sample treatment in aqueous phase with ethyl chloroformate (ECF) derivatization agents. The method has been extensively optimized and validated over a broad range
Gary Gang Chen et al.
Methods in molecular biology (Clifton, N.J.), 720, 427-436 (2011-02-15)
There is considerable evidence supporting a role of the polyamine system in the etiology and pathology of mental disorders. Changes in the expression and activity of polyamine anabolic/catabolic enzymes, as well as in the levels of individual polyamines, have been
Ju-Young Park et al.
Biological & pharmaceutical bulletin, 36(2), 252-258 (2012-12-01)
In order to measure the levels of serotonin (5-hydroxyltryptamine, 5-HT), dopamine (DA), 3,4-hydroxyphenylacetic acid (DOPAC), 3-methoxytyramine (3-MT) and homovanillic acid (HVA) simultaneously, an effective derivatization method followed by high-performance liquid chromatography (HPLC) coupled to electrochemical ionization mass spectrometry was used.
Stuart J Khan et al.
Chirality, 26(11), 739-746 (2014-12-17)
Ibuprofen and naproxen are commonly used members of a class of pharmaceuticals known as 2-arylpropionic acids (2-APAs). Both are chiral chemicals and can exist as either of two (R)- and (S)-enantiomers. Enantioselective analyses of effluents from municipal wastewater treatment plants
Guoliang Li et al.
Amino acids, 40(4), 1185-1193 (2010-09-17)
Analysis of trace amino acids (AA) in physiological fluids has received more attention, because the analysis of these compounds could provide fundamental and important information for medical, biological, and clinical researches. More accurate method for the determination of those compounds
Fatemeh Oroojalian et al.
Journal of controlled release : official journal of the Controlled Release Society, 288, 45-61 (2018-09-02)
In the current study, thermoresponsive poly(N-isopropylacrylamide)-doxorubicin (PNIPAM-DOX) hydrogel was synthesized and loaded into pH-responsive poly ethylene glycol)-2,4,6- trimethoxy benzylidene pentaerythritol carbonate (PEG-PTMBPEC) polymersomes in order to fabricate a smart thermo-pH stimuli responsive drug delivery system. Thermo-pH responsive polymersomal formulation of
P Husek et al.
Journal of chromatography. B, Biomedical sciences and applications, 693(2), 499-502 (1997-06-06)
Following deproteinization of plasma with organic solvents the supernatant was shaken with hexane and cation-exchange resin in an Eppendorf tube to remove fatty and amino acids and the medium was subjected to direct treatment with ethyl chloroformate under catalytic influence
Ruth S Croxton et al.
Journal of forensic sciences, 51(6), 1329-1333 (2007-01-04)
Latent fingerprint residue is a complex mixture of organic and inorganic compounds. A full understanding of the composition of this mixture and how it changes after deposition is lacking. Three solvent systems were compared for the simultaneous extraction and derivatization
Kwon-Chul Noh et al.
The Analyst, 140(24), 8209-8216 (2015-11-12)
A simple and sensitive colorimetric method for the determination of Pb(2+) ions in aqueous samples was developed using 1-(2-mercaptoethyl)-1,3,5-triazinane-2,4,6-trione (MTT) functionalized silver nanoparticles (MTT-AgNPs). The Pb(2+) ion acted as the metal center of the coordination complex, which formed N-Pb(2+)-O coordination
Mohana Krishna Reddy Mudiam et al.
Journal of pharmaceutical and biomedical analysis, 70, 310-319 (2012-06-09)
The present article reports first time the use of solid-phase microextraction (SPME) and dispersive liquid-liquid microextraction (DLLME) to extract pregabalin (PRG) from urine and pharmaceutical formulations followed by GC-MS analysis after ethyl chloroformate (ECF) derivatization. PRG is an antiepileptic and
Dip-Pen Nanolithography of Chemical Templates on Silicon Oxide.
Kooi SE, et al.
Advanced Materials, 16(12), 1013-1016 (2004)
Roney dos Santos Ramos et al.
Molecular reproduction and development, 81(7), 584-594 (2014-03-25)
The timing and magnitude of exposure to preovulatory estradiol followed by post-ovulatory progesterone (periovulatory endocrine milieu) in cattle modulate endometrial gene expression, histotroph composition, and conceptus development, but the mechanisms underlying this regulation remain unknown. Using an experimental model based
Guo-Xiang Xie et al.
Journal of pharmaceutical and biomedical analysis, 43(3), 920-925 (2006-10-13)
Dencichine (beta-N-oxalyl-l-alpha,beta-diaminopropionic acid) is a haemostatic agent present in well-known traditional Chinese medicinal herbs such as Panax notoginseng, as well as other Panax species. It is also a reported neurotoxic agent found in Lathyrus sativus (grass pea seed) and cycad
Mohana Krishna Reddy Mudiam et al.
Analytical and bioanalytical chemistry, 401(5), 1695-1701 (2011-07-12)
A simple and rapid analytical method based on in-matrix ethyl chloroformate (ECF) derivatization has been developed for the quantitative determination of bisphenol-A (BPA) in milk and water samples. The samples containing BPA were derivatised with ECF in the presence of
Cheong Hoon Lee et al.
Talanta, 129, 552-559 (2014-08-17)
Because of the high stability and potential toxic effects of non-steroidal anti-inflammatory drugs (NSAIDs), it is important to closely monitor their concentrations in the environment using a sensitive analytical method. In this study, a simple, rapid, efficient, and sensitive analytical
Mohana Krishna Reddy Mudiam et al.
Analytical and bioanalytical chemistry, 405(1), 341-349 (2012-10-20)
The present communication describes the preparation and evaluation of a molecularly imprinted polymer (MIP) as a solid-phase extraction (SPE) sorbent and simultaneous ethyl chloroformate (ECF) derivatization and pre-concentration by dispersive liquid-liquid microextraction (DLLME) for the analysis of t,t-muconic acid (t,t-MA)
Mohammad Yar Khuhawar et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 24(11), 1493-1496 (2008-11-11)
Ethyl chloroformate was examined as a precolumn derivatizing reagent for the gas chromatographic (GC) determination of isoniazid (INH) and hydrazine (HZ). Phenylhydrazine (PHZ) was used as an internal standard. GC separation was carried out on an HP-5 column (30 m
Heidi S Marks et al.
Journal of AOAC International, 89(6), 1591-1599 (2007-01-18)
A gas chromatography-mass spectrometry (GC/MS) method is described for the easy rapid determination and simultaneous confirmation of the biogenic amines putrescine (PUT), cadaverine (CAD), histamine (HTA), and spermidine (SPD) in fresh frozen tuna loin. The method can also be used
Harald Unterweger et al.
International journal of nanomedicine, 10, 6985-6996 (2015-12-10)
Combining the concept of magnetic drug targeting and photodynamic therapy is a promising approach for the treatment of cancer. A high selectivity as well as significant fewer side effects can be achieved by this method, since the therapeutic treatment only
M S Louie et al.
Nucleosides, nucleotides & nucleic acids, 20(4-7), 1099-1102 (2001-09-21)
1-[((S)-2-Hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine (cyclic HPMPC) was readily synthesized in gram to multi-kilogram quantities by treating a DMF suspension of HPMPC with four molar equivalents of ethyl chloroformate. This dehydrative intramolecular cyclization process typically afforded cHPMPC in 94% isolated yield and high
Cuihua Song et al.
International journal of food sciences and nutrition, 63(2), 170-177 (2011-08-31)
Amino acids (AA) are important chemical constituents of tea leaves remarkably influencing the quality of tea. In this study, free AA and total AA in Apocynum venetum L. (Luobuma tea) were estimated by HPLC equipped with fluorescent detector using 2-[2-(7H-dibenzo[a,g]carbazol-7-yl)-ethoxy]
Eleni Kouloumpi et al.
Analytical and bioanalytical chemistry, 387(3), 803-812 (2006-11-08)
Gas chromatographic analysis of ethyl chloroformate derivatives of samples taken from the paint layers of post-Byzantine panel paintings permitted the successful characterisation of the different binding media used in them. This paper describes an analytical study of various post-Byzantine binding
Gary G Chen et al.
Journal of mass spectrometry : JMS, 44(8), 1203-1210 (2009-06-11)
A quantitative method for putrescine (PUT), spermidine (SPD) and spermine (SPM) in homogenized postmortem human brain tissue is described that employs a novel, simple and rapid extractive derivatization with ethylchloroformate and trifluoroacetylation. These amines are metabolites of ornithine and are
Porkodi Kadhirvel et al.
Journal of chromatography. A, 1358, 93-101 (2014-07-22)
Straightforward crushing and sieving bulk polymeric R-aminoglutethimide-imprinted materials were prepared by classical free radical polymerization, whereas nano thin walled grafted imprinted materials were prepared using RAFT mediated control polymerization technique. A stoichiometric non-covalent approach based on a triply hydrogen bonding
Jianjun Zhang et al.
Carbohydrate research, 342(6), 797-805 (2007-02-16)
A highly regio- and stereoselective anomeric esterification of 3-O-allyl (or benzyl, or benzoyl)-4,6-O-isopropylidene-alpha,beta-d-glucopyranose with acetyl chloride, or allyl chloroformate, or ethyl chloroformate gave the corresponding 2-OH, 1-beta-acetates or -carbonates in excellent yields. The 2-OH, 1-beta-acetates were readily converted to the
Mohana Krishna Reddy Mudiam et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 907, 56-64 (2012-09-25)
Amino acids play a vital role as intermediates in many important metabolic pathways such as the biosynthesis of nucleotides, vitamins and secondary metabolites. A sensitive and rapid analytical method has been proposed for the first time for the simultaneous determination
Jin Woo Park et al.
Archives of pharmacal research, 37(12), 1560-1569 (2013-11-21)
Risedronate is widely used clinically to treat osteoporosis, Paget's disease, hypercalcemia, bone metastasis, and multiple myeloma. However, its oral efficacy is restricted due to its low bioavailability and severe gastrointestinal adverse effects. This study was designed to evaluate the effect
Mi Hye Seong et al.
International journal of molecular sciences, 10(3), 929-941 (2009-04-29)
The specific rates of solvolysis of ethyl fluoroformate have been measured at 24.2 degrees C in 21 pure and binary solvents. These give a satisfactory correlation over the full range of solvents when the extended Grunwald-Winstein equation is applied. The
M R Wright et al.
Journal of chromatography, 616(1), 59-65 (1993-06-23)
A potential problem with chiral derivatization is the possibility of stereochemical conversion during the derivatization reaction. This possibility has been examined using the non-steroidal anti-inflammatory drugs ibuprofen, ketoprofen, etodolac and flurbiprofen. To avoid possible interference from stereochemical impurities, male Sprague-Dawley
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