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Showing 1-6 of 6 results for "200-219-3" within Papers
R Zahn et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(1), 145-150 (2000-01-05)
The NMR structures of the recombinant human prion protein, hPrP(23-230), and two C-terminal fragments, hPrP(90-230) and hPrP(121-230), include a globular domain extending from residues 125-228, for which a detailed structure was obtained, and an N-terminal flexibly disordered "tail." The globular
Chieko Makino et al.
Psychiatric genetics, 15(3), 215-221 (2005-08-12)
The glutamatergic dysfunction is one of the main hypotheses for the pathophysiology of schizophrenia. N-methyl-D-aspartate receptors are of major interest because phencyclidine, a non-competitive antagonist of N-methyl-D-aspartate receptors, produces a schizophrenia-like psychosis. Therefore, the genes encoding N-methyl-D-aspartate receptor subunits are
Stephen A Harrison et al.
Gastroenterology, 155(4), 1140-1153 (2018-07-11)
Lysyl oxidase-like 2 contributes to fibrogenesis by catalyzing cross-linkage of collagen. We evaluated the safety and efficacy of simtuzumab, a monoclonal antibody against lysyl oxidase-like 2, in two phase 2b trials of patients with advanced fibrosis caused by nonalcoholic steatohepatitis.
Sang In Park et al.
Journal of biomedicine & biotechnology, 2010, 893401-893401 (2011-01-29)
Sodium ozagrel (SO) prevents platelet aggregation and vasoconstriction in the cerebral ischemia. It plays an important role in the prevention of brain damage induced by cerebral ischemia/reperfusion. Recently, many animal studies have suggested that the Panax ginseng (PG) has neuroprotective
Xingrong Liu et al.
Drug metabolism and disposition: the biological fate of chemicals, 48(5), 408-419 (2020-03-07)
The objectives of the present study were to characterize GNE-947 for its phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitory activities, in vitro anti-cell migration activity in human umbilical vein endothelial cells (HUVECs), in vivo antineovascularization activity in
Almahamoudou Mahamar et al.
Malaria journal, 20(1), 23-23 (2021-01-09)
More than 200 million people live in areas of highly seasonal malaria transmission where Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) was recommended in 2012 by WHO. This strategy is now implemented widely and protected more than
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