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Showing 1-30 of 355 results for "201030" within Papers
Mark E Koina et al.
Investigative ophthalmology & visual science, 56(2), 1310-1327 (2015-01-15)
Lymphatics subserve many important functions in the human body including maintenance of fluid homeostasis, immune surveillance, and tumor metastasis. Our aim was to provide structural and phenotypic evidence of lymphatic-like structures in the human choroid, including details of its development.
Hang Su et al.
International journal of nanomedicine, 10, 1921-1930 (2015-03-21)
Vaccines play important roles in antitumor biotherapy. Autophagy in tumor cells plays a critical role in depredating proteins, including tumor-specific antigens and tumor-associated antigens. We aimed to induce and collect tumor-derived autophagosomes (DRibbles) from tumor cells as a novel antitumor
Fan He et al.
The Journal of endocrinology, 223(2), 167-180 (2014-09-12)
Both self-renewal and lineage-specific differentiation of mesenchymal stem cells (MSCs) are triggered by their in vivo microenvironment including the extracellular matrix (ECM) and secreted hormones. The ECM may modulate the physiological functions of hormones by providing binding sites and by
Papia Chakraborty et al.
Molecular endocrinology (Baltimore, Md.), 28(7), 1055-1072 (2014-05-16)
Sertoli cell tight junctions (SCTJs) of the seminiferous epithelium create a specialized microenvironment in the testis to aid differentiation of spermatocytes and spermatids from spermatogonial stem cells. SCTJs must be chronically broken and rebuilt with high fidelity to allow the
Mayara Klimuk Uchiyama et al.
Toxicological sciences : an official journal of the Society of Toxicology, 142(2), 497-507 (2014-09-28)
Gold nanoparticle (AuNP) bioconjugates have been used as therapeutic and diagnostic tools; however, in vivo biocompatibility and cytotoxicity continue to be two fundamental issues. The effect of AuNPs (20 nm) conjugated with antibody [immunoglobulin G (IgG)], albumin, protein A, PEG4000, and citrate
Qi Dong et al.
Journal of translational medicine, 12, 323-323 (2014-11-27)
Cardiac hypertrophy is a compensatory stage of the heart in response to stress such as pressure overload (PO), which can develop into heart failure (HF) if left untreated. Resveratrol has been reported to prevent the development of hypertrophy and contractile
Andrew P Holmes et al.
The Journal of physiology, 592(20), 4493-4506 (2014-07-27)
The view that the carotid body (CB) type I cells are direct physiological sensors of hypoglycaemia is challenged by the finding that the basal sensory neuronal outflow from the whole organ is unchanged in response to low glucose. The reason
Fumito Sakamoto et al.
Cytotechnology, 67(1), 75-84 (2013-12-07)
We compared the osteoblastic differentiation abilities of dedifferentiated fat cells (DFATs) and human bone marrow mesenchymal stem cells (hMSCs) as a cell source for bone regeneration therapies. In addition, the utility of DFATs in bone tissue engineering in vitro was
Rinrada Pattanayaiying et al.
International journal of food microbiology, 188, 135-146 (2014-08-12)
The effects of lauric arginate (LAE) and nisin Z, alone or in combination, on cell damage were investigated against Escherichia coli O157:H7, Listeria monocytogenes and Brochothrix thermosphacta, by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) observations, efflux of
Tamara Muñoz-Caro et al.
Parasites & vectors, 8, 607-607 (2015-11-28)
Polymorphonuclear neutrophil (PMN) and eosinophil extracellular trap (ETs) formation has recently been described as an important host effector mechanism against invading pathogens. So far, scarce evidence on metazoan-triggered ET formation has been published. We here describe for the first time
Laura Antonucci et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(45), E6166-E6174 (2015-10-30)
Pancreatic acinar cells possess very high protein synthetic rates as they need to produce and secrete large amounts of digestive enzymes. Acinar cell damage and dysfunction cause malnutrition and pancreatitis, and inflammation of the exocrine pancreas that promotes development of
Thomas Kurth et al.
Protist, 163(2), 296-305 (2011-07-19)
Fixation and preparation for electron microscopy of coccidian oocysts is a general problem. Especially in sporulated oocysts, proper fixation and resin infiltration are hindered by the robust oocyst wall. Conventional chemical fixation therefore leads to artefacts that obscure cellular details
Michael Bezuidenhout et al.
PloS one, 9(9), e108006-e108006 (2014-09-23)
Group IV Nanowires have strong potential for several biomedical applications. However, to date their use remains limited because many are synthesised using heavy metal seeds and functionalised using organic ligands to make the materials water dispersible. This can result in
Boaz Arzi et al.
Stem cells and development, 24(7), 814-823 (2014-11-19)
Mesenchymal stem cells (MSCs) are a promising therapeutic option for various immune-mediated and inflammatory disorders due to their potent immunomodulatory and trophic properties. Naturally occurring diseases in large animal species may serve as surrogate animal models of human disease, as
Louise Hansen et al.
Scandinavian journal of clinical and laboratory investigation, 74(5), 437-446 (2014-04-17)
To evaluate survival and engraftment of mesenchymal stromal cells (MSCs) in vivo, it is necessary to track implanted cells non-invasively with a method, which does not influence cellular ultrastructure and functional characteristics. Iron-oxide particles have been applied for cell tracking
Maria Andree et al.
The EMBO journal, 33(19), 2171-2187 (2014-07-25)
The X-linked inhibitor of apoptosis protein (XIAP) is a potent caspase inhibitor, best known for its anti-apoptotic function in cancer. During apoptosis, XIAP is antagonized by SMAC, which is released from the mitochondria upon caspase-mediated activation of BID. Recent studies
Basma M Khoury et al.
Connective tissue research, 56(2), 106-119 (2015-02-04)
Advances in computed tomography (CT) imaging are opening new avenues toward more precise characterization and quantification of connective tissue microarchitecture. In the last two decades, micro-computed tomography (microCT) has significantly augmented destructive methods for the 3D micro-analysis of tissue structure
Tijna Alekseeva et al.
Tissue engineering. Part A, 20(19-20), 2656-2665 (2014-04-02)
Previous studies have shown that plastic compression (PC) of collagen gels allows a rapid and controlled fabrication of matrix- and cell-rich constructs in vitro that closely mimic the structure and characteristics of tissues in vivo. Microvascular endothelial cells, the major
Luminita David et al.
Colloids and surfaces. B, Biointerfaces, 122, 767-777 (2014-09-02)
This research aimed at reporting the synthesis, characterization and evaluation of the anti-inflammatory effects of some new biomaterials based on silver nanoparticles and polyphenols rich natural extracts. A fast and eco-friendly extracellular biosynthesis of silver nanoparticles (AgNPs), using European black
Karim Arafah et al.
Omics : a journal of integrative biology, 18(8), 487-498 (2014-06-07)
Lipid-based biomarkers for research and diagnosis are rapidly emerging to unpack the basis of person-to-person and population variations in disease susceptibility, drug and nutritional responses, to name but a few. Hence, with the advent of MALDI Mass Spectrometry Imaging, lipids
Igor Makarovsky et al.
The Israel Medical Association journal : IMAJ, 9(10), 750-752 (2007-11-09)
OsO4 is a powerful oxidizer. It affects mainly the skin and mucous membranes. Although unsuitable for a large-scale terrorist attack, mainly due to its scarcity, it could be used in small-scale attacks. The small quantity contained in a vial would
Ulrich Thormann et al.
BioMed research international, 2015, 943603-943603 (2015-02-27)
Screws for ligament reconstruction are nowadays mostly made of poly-L-lactide (PLLA). However, magnesium-based biomaterials are gathering increased interest in this research field because of their good mechanical property and osteoanabolic influence on bone metabolism. The aim of this pilot study
Zachary Yu-Ching Lin et al.
Developmental biology, 400(1), 43-58 (2015-01-28)
Mammalian spermatogenesis has been investigated extensively in rodents and a strictly controlled developmental process has been defined at cellular and molecular levels. In comparison, primate spermatogenesis has been far less well characterized. However, important differences between primate and rodent spermatogenesis
Debby Laukens et al.
Laboratory investigation; a journal of technical methods and pathology, 94(12), 1419-1430 (2014-10-14)
Ulcerative colitis (UC) is characterized by increased epithelial cell death and subsequent breakdown of the intestinal epithelial barrier, which perpetuates chronic intestinal inflammation. Since fecal bile acid dysmetabolism is associated with UC and tauroursodeoxycholic acid (TUDCA) has been shown to
Malgorzata Kotula-Balak et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(3), 529-537 (2015-01-03)
Our previous studies revealed that in bank vole testicular cells octylphenol (OP) action is related either to its binding to estrogen receptors or increasing cAMP level that modulates spermatozoa motility and acrosome reaction (AR), (Kotula-Balak et al., 2011, 2014). To
Noriko Koganezawa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(48), 15860-15874 (2015-12-04)
The postrhinal cortex (POR) provides substantial input to the entorhinal cortex, mainly targeting superficial layers of the medial entorhinal cortex (MEC). Major inputs to POR originate in the visual and parietal cortex, thus providing neurons in MEC with a subset
Brian Mocca et al.
Nitric oxide : biology and chemistry, 51, 52-62 (2015-11-06)
In humans, the free radical nitric oxide (NO) is a concentration-dependent multifunctional signaling or toxic molecule that modulates various physiological and pathological processes, and innate immunity against bacterial infections. Because the expression of bacterial genes encoding nitrite reductase (AniA) and
Yichao Jin et al.
Journal of neurotrauma, 32(14), 1090-1100 (2015-05-06)
Here, we evaluated changes in autophagy after post-traumatic brain injury (TBI) followed by moderate hypothermia in rats. Adult male Sprague-Dawley rats were randomly divided into four groups: sham injury with normothermia group (37 °C); sham injury with hypothermia group (32
Hwang, K.C.
Journal of the Chemical Society. Chemical Communications, 173-173 (1995)
Sophie Sagnier et al.
Journal of virology, 89(1), 615-625 (2014-10-24)
Autophagy is a ubiquitous mechanism involved in the lysosomal-mediated degradation of cellular components when they are engulfed in vacuoles called autophagosomes. Autophagy is also recognized as an important regulator of the innate and adaptive immune responses against numerous pathogens, which
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