206-271-3

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Hydrogen sulphide as a novel therapy to ameliorate cyclosporine nephrotoxicity.

Gwyn Lee et al.

The Journal of surgical research, 197(2), 419-426 (2015-05-21)

Calcineurin inhibitors have significant nephrotoxic side effects, which can exacerbate ischemia-reperfusion injury in renal transplantation. Novel therapeutic agents such as hydrogen sulphide (H₂S) may reduce these harmful effects. This study investigated the effects of H₂S on cyclosporine (CsA) induced nephrotoxicity.

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