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Showing 1-30 of 340 results for "208868" within Papers
F Salamanna et al.
Connective tissue research, 56(1), 35-43 (2014-10-22)
The purpose of this study was to investigate tenocyte mechanobiology after sudden-detraining and to examine the hypothesis that repeated peri-patellar injections of hyaluronic acid (HA) on detrained patellar tendon (PT) may reduce and limit detrained-associated damage in tenocytes. Twenty-four male
Alicia Sampieri et al.
BMC biochemistry, 16, 5-5 (2015-02-05)
Baculoviruses are widely used for the production of recombinant proteins, biopesticides and as gene delivery systems. One of the viral forms called polyhedra has been recently exploited as a scaffold system to incorporate or encapsulate foreign proteins or peptide fragments.
Dongliang Xiong et al.
Plant, cell & environment, 38(12), 2541-2550 (2015-04-30)
Photosynthesis in C3 plants is significantly limited by mesophyll conductance (gm ), which can vary with leaf anatomical traits and nitrogen (N) supplements. Several studies have investigated the response of gm to N supplements; however, none examined the implications of
Andrew B Allison et al.
Journal of virology, 89(2), 1389-1403 (2014-11-14)
Since 1998, cyclic mortality events in common eiders (Somateria mollissima), numbering in the hundreds to thousands of dead birds, have been documented along the coast of Cape Cod, MA, USA. Although longitudinal disease investigations have uncovered potential contributing factors responsible
Desyree Murta Jesus et al.
Journal of virology, 88(24), 14017-14029 (2014-09-26)
Electron micrographs from the 1960s revealed the presence of an S-shaped tubular structure in the center of the vaccinia virion core. Recently, we showed that packaging of virus transcription enzymes is necessary for the formation of the tubular structure, suggesting
Longhai Qiu et al.
Annals of biomedical engineering, 43(12), 2924-2940 (2015-05-28)
Our group pioneered the study of nerve regeneration in China and has successfully developed human "acellular nerve grafts (ACNGs)". However, our clinical studies revealed that the effects of ACNGs for long and large nerve defects are far from satisfactory. To
O N Ponamoreva et al.
Biosensors & bioelectronics, 67, 321-326 (2014-09-10)
The methylotrophic Pichia angusta VKM Y-2559 and the oleaginous Cryptococcus curvatus VKM Y-3288 yeast cells were immobilized in a bimodal silica-organic sol-gel matrix comprised of tetraethoxysilane (TEOS), the hydrophobic additive methyltriethoxysilane (MTES) and the porogen polyethylene glycol (PEG). Under carefully
Cornelia Neidlinger-Wilke et al.
Spine, 39(17), 1355-1364 (2014-05-17)
Conditioned media (CM) of cartilaginous endplates (CEPs) of intervertebral discs were analyzed in a bioassay with regard to their influence on matrix turnover and inflammatory factors on nucleus pulposus (NP) cells of the same patient. CEP tissue underwent further histological
Kotaro Mori et al.
Scientific reports, 5, 9163-9163 (2015-03-17)
The population of influenza virus consists of a huge variety of variants, called quasispecies, due to error-prone replication. Previously, we reported that progeny virions of influenza virus become infected to adjacent cells via cell-to-cell transmission pathway in the presence of
Alejandro Cerrada et al.
PloS one, 9(10), e110195-e110195 (2014-10-22)
Lung alveolar type II (ATII) cells are specialized in the synthesis and secretion of pulmonary surfactant, a lipid-protein complex that reduces surface tension to minimize the work of breathing. Surfactant synthesis, assembly and secretion are closely regulated and its impairment
Henrieke Sievers et al.
Clinical hemorheology and microcirculation, 61(2), 367-383 (2015-10-08)
Human microvascular ECs from the neonatal foreskin of two donors purchased from one distributor were used in an angiogenesis assay under the same culture conditions. Different angiogenic potency was apparent in these two batches (ECang and ECnon-ang). During the cultivation
Asymmetric induction in the reaction of osmium tetroxide with olefins.
Hentges SG and Barry Sharpless K.
Journal of the American Chemical Society, 102(12), 4263-4265 (1980)
Alain C Burette et al.
The Journal of comparative neurology, 520(12), 2697-2711 (2012-06-12)
Synaptic function depends on interactions among sets of proteins that assemble into complex supramolecular machines. Molecular biology, electrophysiology, and live-cell imaging studies have provided tantalizing glimpses into the inner workings of the synapse, but fundamental questions remain regarding the functional
Lei Wang et al.
PloS one, 10(2), e0118134-e0118134 (2015-02-18)
Diabetic peripheral neuropathy is a common complication of long-standing diabetes mellitus. To mimic clinical trials in which patients with diabetes enrolled have advanced peripheral neuropathy, we investigated the effect of sildenafil, a specific inhibitor of phosphodiesterase type 5 enzyme, on
Xiaoyan Bai et al.
American journal of nephrology, 40(6), 523-534 (2015-01-13)
Vascular endothelial growth factor-A (VEGF-A) upregulation and podocyte apoptosis have been documented in diabetes. This study was designed to investigate whether inhibiting VEGF-A could ameliorate podocyte apoptosis in diabetes and the underlying mechanisms. In vitro, small interfering RNAs (siRNAs) of
Courtney Reichhardt et al.
Biochimica et biophysica acta, 1848(1 Pt B), 378-383 (2014-06-10)
Bacterial biofilms are communities of bacterial cells surrounded by a self-secreted extracellular matrix. Biofilm formation by Vibrio cholerae, the human pathogen responsible for cholera, contributes to its environmental survival and infectivity. Important genetic and molecular requirements have been identified for
Song-Fa Zhang et al.
Autophagy, 11(2), 225-238 (2015-01-22)
Paclitaxel is recommended as a first-line chemotherapeutic agent against ovarian cancer, but drug resistance becomes a major limitation of its success clinically. The key molecule or mechanism associated with paclitaxel resistance in ovarian cancer still remains unclear. Here, we showed
Sreejit Parameswaran et al.
Analytical biochemistry, 416(2), 186-190 (2011-06-21)
The lack of an established protocol for scanning electron microscopy (SEM) studies on stem cells differentiating into adipogenic lineage led us to develop a protocol for the preparation of differentiated adult bone marrow-derived mesenchymal stem cells (BMSC) for SEM. This
Teresa Vanessa Fiorentino et al.
The American journal of pathology, 185(1), 139-150 (2014-12-03)
In this study, we aimed to evaluate the effects of exenatide (EXE) treatment on exocrine pancreas of nonhuman primates. To this end, 52 baboons (Papio hamadryas) underwent partial pancreatectomy, followed by continuous infusion of EXE or saline (SAL) for 14
Ang Tian et al.
International journal of nanomedicine, 10, 2423-2439 (2015-04-08)
Cells respond to their surroundings through an interactive adhesion process that has direct effects on cell proliferation and migration. This research was designed to investigate the effects of TiO2 nanotubes with different topographies and structures on the biological behavior of
Lucas N L Van Aelst et al.
Circulation research, 116(3), 425-436 (2014-12-19)
To maintain cardiac mechanical and structural integrity after an ischemic insult, profound alterations occur within the extracellular matrix. Osteoglycin is a small leucine-rich proteoglycan previously described as a marker of cardiac hypertrophy. To establish whether osteoglycin may play a role
B Šošić-Jurjević et al.
Experimental gerontology, 72, 85-98 (2015-09-19)
We previously reported that orchidectomy (Orx) of middle-aged rats (15-16-month-old; MA) slightly affected pituitary-thyroid axis, but decreased liver deiodinase (Dio) type 1 and pituitary Dio2 enzyme activities. At present, we examined the effects of subsequent testosterone-propionate treatment (5mg/kg; Orx+T), and
Carla J Abbott et al.
PloS one, 9(12), e114546-e114546 (2014-12-17)
To compare in young and old rats longitudinal measurements of retinal nerve fiber layer thickness (RNFLT) and axonal transport 3-weeks after chronic IOP elevation. IOP was elevated unilaterally in 2- and 9.5-month-old Brown-Norway rats by intracameral injections of magnetic microbeads.
Robert Farkaš et al.
PloS one, 9(4), e94383-e94383 (2014-04-16)
In contrast to the well defined mechanism of merocrine exocytosis, the mechanism of apocrine secretion, which was first described over 180 years ago, remains relatively uncharacterized. We identified apocrine secretory activity in the late prepupal salivary glands of Drosophila melanogaster
Sandra L Johnson
Methods in molecular biology (Clifton, N.J.), 1001, 325-340 (2013-03-16)
Scanning electron microscopy (SEM) is an important technique for evaluation of the efficiency of endothelialization of tissue-engineered constructs incorporating a surface endothelial cell layer. Here, we describe methodologies for the preparation of such constructs for SEM analysis that are applicable
Yong-Gyun Jung et al.
Applied and environmental microbiology, 81(1), 211-219 (2014-10-19)
A variety of systems have been developed to study biofilm formation. However, most systems are based on the surface-attached growth of microbes under shear stress. In this study, we designed a microfluidic channel device, called a microfluidic agarose channel (MAC)
Jia Huang et al.
Molecular medicine reports, 11(3), 1777-1783 (2014-11-08)
The aim of the present study was to investigate the morphological characteristics and pluripotent differentiation potential of human bone marrow mesenchymal stem cells (hBMMSCs) in vitro and in vivo. Bone marrow cells were isolated from a rib fragment of an
Chiung-Chyi Shen et al.
Journal of biomedical materials research. Part A, 101(1), 239-252 (2012-08-14)
This paper proposes a novel biodegradable nerve conduit comprising 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) cross-linked gelatin, annexed with β-tricalcium phosphate (TCP) ceramic particles (EDC-Gelatin-TCP, EGT). In this study, the EGT-implant site in rats was irradiated using a large-area 660 nm AlGaInP diode
Mario Ledda et al.
Tissue engineering. Part C, Methods, 21(2), 207-217 (2014-08-05)
In vivo control of osteoblast differentiation is an important process needed to maintain the continuous supply of mature osteoblast cells for growth, repair, and remodeling of bones. The regulation of this process has also an important and significant impact on
Caroline Kizilyaprak et al.
Journal of structural biology, 189(2), 135-146 (2014-11-30)
In the last two decades, the third-dimension has become a focus of attention in electron microscopy to better understand the interactions within subcellular compartments. Initially, transmission electron tomography (TEM tomography) was introduced to image the cell volume in semi-thin sections
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