231-193-1

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Showing 1-6 of 6 results for "231-193-1" within Papers

Active-site peptides of acetylcholinesterase of Electrophorus electricus: labelling of His-440 by 1-bromo-[2-14C]pinacolone and Ser-200 by tritiated diisopropyl fluorophosphate.

E Salih et al.

Biochimica et biophysica acta, 1208(2), 324-331 (1994-10-19)

To characterize the structure of the active site of acetylcholinesterase (AChE) from the electric organ of E. electricus, we identified sites of incorporation of two active-site affinity labels, [3H]diisopropyl fluorophosphate ([3H]DFP), and 1-bromo-2-[14C]pinacolone ([14C]BrPin). AChE was isolated, purified, inactivated and

Dynamics and timing of in vivo mutations at Gag residue 242 during primary HIV-1 subtype C infection.

Vladimir Novitsky et al.

Virology, 403(1), 37-46 (2010-05-07)

Viral mutations at Gag residue 242 and relevant viral polymorphisms were analyzed in a cohort of 42 individuals with primary HIV-1 subtype C infection using single-genome amplification/sequencing. In HLA-B*57/5801-negative subjects infected with 242N escape variant, reversion to Asn appeared at

Serum glutathione S-transferase P1 1 in prediction of cardiac function.

Olena Andrukhova et al.

Journal of cardiac failure, 18(3), 253-261 (2012-03-06)

Glutathione S-transferase P1 1 (GSTP1) belongs to the multigene isozyme family involved in cellular response to oxidative stress and apoptosis. Our initial retrospective proteomic analysis suggested that GSTP1 is associated with heart failure (HF). Although pro-B-type natriuretic peptide (proBNP) serves

Human paraoxonase 1 hydrolysis of nanomolar chlorpyrifos-oxon concentrations is unaffected by phenotype or Q192R genotype.

R Hunter Coombes et al.

Toxicology letters, 230(1), 57-61 (2014-08-06)

The organophosphorus insecticide chlorpyrifos has been widely used. Its active metabolite chlorpyrifos-oxon (CPO) is a potent anticholinesterase and is detoxified by paraoxonase 1 (PON1). PON1 activity is influenced by numerous factors including a Q192R polymorphism. Using forty human blood samples

Signal- and importin-dependent nuclear targeting of the kidney anion exchanger 1-binding protein kanadaptin.

Stefan Hübner et al.

The Biochemical journal, 361(Pt 2), 287-296 (2002-01-05)

Kanadaptin (kidney anion exchanger adaptor protein) has recently been identified as a protein with binding activity to the cytoplasmic domain of the kidney Na(+)-independent Cl(-)/HCO(-)(3) anion exchanger 1 (kAE1). Since it is widely expressed in tissues devoid of kAE1, however

Simvastatin for the prevention of exacerbations in moderate-to-severe COPD.

Gerard J Criner et al.

The New England journal of medicine, 370(23), 2201-2210 (2014-05-20)

Retrospective studies have shown that statins decrease the rate and severity of exacerbations, the rate of hospitalization, and mortality in chronic obstructive pulmonary disease (COPD). We prospectively studied the efficacy of simvastatin in preventing exacerbations in a large, multicenter, randomized

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