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Showing 1-30 of 220 results for "244686" within Papers
Elisabeth Darrouzet et al.
Biochimica et biophysica acta, 1838(1 Pt B), 244-253 (2013-08-31)
The sodium/iodide symporter (NIS or SLC5A5) is an intrinsic membrane protein implicated in iodide uptake into thyroid follicular cells. It plays a crucial role in iodine metabolism and thyroid regulation and its function is widely exploited in the diagnosis and
Nicole Li et al.
American heart journal, 166(5), 815-822 (2013-11-02)
Cardiovascular diseases are the leading cause of death and disability in China. High blood pressure caused by excess intake of dietary sodium is widespread and an effective sodium reduction program has potential to improve cardiovascular health. This study is a
I M Larina et al.
Fiziologiia cheloveka, 39(2), 43-59 (2013-06-26)
In the review it was represented the modern ideas on the processes involved in the formation of the protein composition of the urine of healthy people. In the last decade the development of highly sensitive mass spectrometric methods for the
Ben Corry et al.
Handbook of experimental pharmacology, 221, 251-267 (2014-04-17)
The pedigree of voltage-gated sodium channels spans the millennia from eukaryotic members that initiate the action potential firing in excitable tissues to primordial ancestors that act as enviro-protective complexes in bacterial extremophiles. Eukaryotic sodium channels (eNavs) are central to electrical
Stéphane Roger et al.
The European physical journal. E, Soft matter, 38(8), 88-88 (2015-08-13)
We present a structural and a multi-scale rheophysical investigation of magneto-sensitive materials based on biopolymers, namely aqueous solutions of sodium alginate incorporating magnetic maghemite nanoparticles, functionalized with adsorbed negative citrate ions. The large alginate ionic strength impacts the structure and
Robert D Gray et al.
Journal of molecular biology, 426(8), 1629-1650 (2014-02-04)
Sequence analogs of human telomeric DNA such as d[AGGG(TTAGGG)3] (Tel22) fold into monomeric quadruplex structures in the presence of a suitable cation. To investigate the pathway for unimolecular quadruplex formation, we monitored the kinetics of K(+)-induced folding of Tel22 by
Amiraj Banga et al.
American journal of physiology. Lung cellular and molecular physiology, 306(10), L937-L946 (2014-04-08)
Calu-3 is a well-differentiated human bronchial cell line with the characteristics of the serous cells of airway submucosal glands. The submucosal glands play a major role in mucociliary clearance because they secrete electrolytes that facilitate airway hydration. Given the significance
Umut Yucel et al.
Journal of agricultural and food chemistry, 63(34), 7494-7498 (2015-08-11)
There is a broad need to reformulate lower sodium food products without affecting their original taste. The present study focuses on characterizing the role of protein-salt interactions on the salt release in low-moisture systems and saltiness perception during hydration. Sodium
Liangjie Yin et al.
American journal of physiology. Cell physiology, 306(7), C687-C696 (2014-01-31)
The sodium-coupled glucose transporter-1 (SGLT1)-based oral rehydration solution (ORS) used in the management of acute diarrhea does not substantially reduce stool output, despite the fact that glucose stimulates the absorption of sodium and water. To explain this phenomenon, we investigated
Colin H Peters et al.
Handbook of experimental pharmacology, 221, 1-6 (2014-04-17)
Voltage-gated sodium channels (VGSCs) are present in many tissue types within the human body including both cardiac and neuronal tissues. Like other channels, VGSCs activate, deactivate, and inactivate in response to changes in membrane potential. VGSCs also have a similar
Aurélien Vidal et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 101, 1-9 (2015-03-31)
The cartilage-targeting strategy is based on the strong affinity of quaternary ammonium (QA) functions for cartilage proteoglycans. We use a bifunctional agent containing QA moiety and a polyazamacrocycle structure able to complex technetium-99m. (99m)Tc-NTP 15-5 was selected for its high
Hwa Yeon Yi et al.
The American journal of emergency medicine, 32(10), 1200-1207 (2014-08-26)
Unlike other sodium-channel-blocking antiarrhythmic agents, propafenone has β-blocking effects and calcium-channel-blocking effects. Yi et al recently studied insulin's treatment effect on acute propafenone toxicity in rats. However, because the degree of effectiveness of insulin compared to the previously known antidote
Zaida Andrés et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), E1806-E1814 (2014-04-16)
Stomatal movements rely on alterations in guard cell turgor. This requires massive K(+) bidirectional fluxes across the plasma and tonoplast membranes. Surprisingly, given their physiological importance, the transporters mediating the energetically uphill transport of K(+) into the vacuole remain to
Liangjie Yin et al.
Health physics, 106(6), 734-744 (2014-04-30)
Electrolyte and nutrient absorption occur in villous epithelial cells. Radiation often results in reduced electrolyte and nutrient absorption, which leads to gastrointestinal toxicity. Therefore, the authors studied: (1) radiation-induced changes in glucose and amino acid absorption across ileal tissues and
Pierre Martin et al.
Chimia, 67(4), 204-206 (2013-08-24)
The total synthesis of protoporphyrin IX and its disodium salt using a new alternative method to the classical MacDonald condensation is reported. The key step is the reaction of the new unsymmetrical diiodo dipyrrylmethane 1 with the known dipyrrylmethane 2.
Srinivas Rengarajan et al.
American journal of physiology. Renal physiology, 306(9), F1059-F1068 (2014-03-07)
Dietary potassium loading results in rapid kaliuresis, natriuresis, and diuresis associated with reduced phosphorylation (p) of the distal tubule Na(+)-Cl(-) cotransporter (NCC). Decreased NCC-p inhibits NCC-mediated Na(+) reabsorption and shifts Na(+) downstream for reabsorption by epithelial Na(+) channels (ENaC), which
Yasser Elshahawy et al.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 24(3), 507-513 (2013-05-04)
To evaluate the individualization of dialysate sodium (Na + ) concentration in hemodialysis (HD), we studied 40 stable chronic HD patients in a single-blind crossover design. They underwent 36 consecutive HD sessions with the dialysate Na + concentration set at
August Wrotek et al.
Advances in experimental medicine and biology, 835, 31-36 (2014-09-26)
Copeptin has been associated with the severity of pneumonia and its complications. This study was designed to assess the usefulness of copeptin measurement in children with community-acquired pneumonia (CAP) and copeptin's relation with disease severity and sodium equilibrium. The study
M Shriver et al.
Oncogene, 34(32), 4248-4259 (2014-11-11)
Obscurins, encoded by the single OBSCN gene, are giant cytoskeletal proteins with structural and regulatory roles. The OBSCN gene is highly mutated in different types of cancers. Loss of giant obscurins from breast epithelial cells confers them with a survival
[The cutting-edge of medicine; novel therapeutic agents for the treatment of diabetes sodium-glucose co-transporter (SGLT) 2 inhibitors].
Toshiro Sugimoto et al.
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(6), 1474-1483 (2013-08-21)
Mette U Anby et al.
Molecular pharmaceutics, 11(11), 4069-4083 (2014-09-30)
The impact of gastrointestinal (GI) processing and first pass metabolism on danazol oral bioavailability (BA) was evaluated after administration of self-emulsifying drug delivery systems (SEDDS) in the rat. Danazol absolute BA was determined following oral and intraduodenal (ID) administration of
Wenqi Wu et al.
Urology, 83(4), 732-737 (2014-02-04)
To assess urine composition in Chinese patients with urolithiasis. Five hundred seven Chinese patients with urolithiasis from our center in southern China were included in this study. Analysis of stone composition was performed using infrared spectrometry. From all patients, 24-hour
Carey A Hobbs et al.
The Journal of physiology, 591(18), 4377-4387 (2013-07-24)
Airway epithelia absorb Na+ through the epithelial Na+ channel (ENaC) and secrete Cl- through the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. This balance maintains sufficient airway surface liquid hydration to permit efficient mucus clearance, which is needed to
Wei-Zhong Ying et al.
American journal of physiology. Renal physiology, 307(1), F58-F63 (2014-05-03)
The amount of Na(+) and K(+) in the diet promotes significant changes in endothelial cell function. In the present study, a series of in vitro and in vivo experiments determined the role of Na(+) and K(+) in the regulation of
Rosalinda Madonna et al.
Vascular pharmacology, 59(5-6), 127-130 (2013-10-22)
Sodium-hydrogen exchangers (NHE) are among the main regulators of cell volume and intracellular concentration of hydrogen and sodium ions. By indirectly affecting sodium/calcium exchange across the plasma membrane, NHE can also influence the intracellular concentration of calcium. Excess activation of
W Xiao et al.
Spinal cord, 55(11), 1028-1032 (2017-06-14)
Experimental study. The aim of this study is to develop a modified model of spinal cord ischemia in rabbits. Shenzhen Key Laboratory of Spine Surgery, Shenzhen, China. In total, 20 New Zealand rabbits were divided into the following four groups
S Franzè et al.
International journal of pharmaceutics, 481(1-2), 79-83 (2015-02-07)
Low molecular weight heparins (LMWHs) are obtained from unfractionated heparin (UFH) through different depolymerization methods (DM), which produce compounds having specific chemical features and biological activity. It is then supposed that LMWHs also exhibit different skin permeability properties. The current
Peng Zhai et al.
Biomedical materials (Bristol, England), 10(4), 045016-045016 (2015-08-05)
The adult mammalian central nervous system has limited ability to regenerate after injury. This is due, in part, to the presence of myelin-associated axon growth inhibitory proteins such as Nogo-A that bind and activate the Nogo receptor, leading to profound
Meng Li et al.
Molecular medicine reports, 18(6), 5784-5790 (2018-11-06)
Apelin has been reported to be associated with multiple physiological processes in the cardiovascular system. The aim of the present study was to investigate the effects of Apelin‑13 administration on cardiac function, hyperglycemia, insulin resistance (IR), dyslipidemia, endothelial function, inflammation
S S Pati et al.
Journal of nanoscience and nanotechnology, 14(6), 4114-4123 (2014-04-18)
We investigate the effect of sodium trapping on thermal stability of magnetite (Fe3O4) nanoparticles. The pure magnetite nanoparticles incubated in sodium hydroxide solutions and subsequently washed with water to remove the excess sodium. The amount of sodium in magnetite is
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