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Showing 1-30 of 143 results for "248649" within Papers
David J Huss et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 84-92 (2014-11-25)
Regulatory T cells (Tregs) mediate immune tolerance to self and depend on IL-2 for homeostasis. Treg deficiency, dysfunction, and instability are implicated in the pathogenesis of numerous autoimmune diseases. There is considerable interest in therapeutic modulation of the IL-2 pathway
Harald Handschuh et al.
International journal of environmental research and public health, 12(11), 13938-13955 (2015-11-04)
The travelling population is increasing globally year on year. International tourist arrival figures reached 1087 million in 2013 and 1133 million in 2014; of which 53% and 54% respectively accounted for air transport. The water on board aircraft is sourced
E Turrini et al.
Journal of ethnopharmacology, 162, 261-269 (2015-01-07)
The decoction of the roots of Hemidesmus indicus is widely used in the Indian traditional medicine for many purposes and poly-herbal preparations containing Hemidesmus are often used by traditional medical practitioners for the treatment of cancer. In the context of
Toshiaki Iwase et al.
Medicine, 93(28), e269-e269 (2014-12-20)
The aim of the present study was to investigate the relationships between the automated bone scan index (aBSI) and skeletal-related events (SRE) in breast cancer patients with bone metastasis. A computer-aided software (BONENAVI™) that was developed using an Artificial Neural
Hydriodic acid to overcome tubal occlusion in sterility.
S S GARRETT
American journal of surgery, 80(1), 131-132 (1950-07-01)
Leah K Gilbert et al.
American journal of preventive medicine, 48(3), 345-349 (2014-10-11)
Adverse childhood experiences (ACEs), including child abuse and family dysfunction, are linked to leading causes of adult morbidity and mortality. Most prior ACE studies were based on a nonrepresentative patient sample from one Southern California HMO. To determine if ACE
Christine M Thompson et al.
Analytical and bioanalytical chemistry, 407(13), 3591-3604 (2015-03-12)
Because bivalve larvae are difficult to identify using morphology alone, the use of Raman spectra to distinguish species could aid classification of larvae collected from the field. Raman spectra from shells of bivalve larvae exhibit bands that correspond to polyene
Marcellin Fotsing et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 46(4), 420-425 (2011-03-11)
In the present work, a high capacity anion exchange column was used to efficiently and simultaneously separate traces of oxyhalide disinfection byproducts (DBP) anions and bromide by an ion chromatography system followed by a post-column reaction (PCR). The PCR generates
Akihiko Takasaki et al.
Pigment cell research, 16(5), 480-486 (2003-09-03)
A sensitive and specific high performance liquid chromatography (HPLC) method was developed to quantify 4-amino-3-hydroxyphenylalanine (4-AHP) and 3-amino-4-hydroxyphenylalanine (3-AHP) in urine. In degradation studies of melanin pigment, 4-AHP and 3-AHP are derived from benzothiazine units of pheomelanin and pheomelanin-related metabolites
Imen Louati et al.
PloS one, 10(11), e0140614-e0140614 (2015-11-19)
The factors and processes driving cyanobacterial blooms in eutrophic freshwater ecosystems have been extensively studied in the past decade. A growing number of these studies concern the direct or indirect interactions between cyanobacteria and heterotrophic bacteria. The presence of bacteria
Richard J Bodnar
Peptides, 62, 67-136 (2014-09-30)
This paper is the thirty-sixth consecutive installment of the annual review of research concerning the endogenous opioid system. It summarizes papers published during 2013 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides, opioid receptors
Shabarish Thatipamula et al.
Neurobiology of disease, 75, 15-30 (2015-01-03)
Neonatal hypoxic-ischemic (HI) brain injury is a leading cause of mortality and morbidity in infants and children for which there is no promising therapy at present. Previously, we reported induction of neuronal pentraxin 1 (NP1), a novel neuronal protein of
Hong-Shuo Sun et al.
Experimental neurology, 263, 161-171 (2014-12-03)
Neonatal hypoxic-ischemic brain injury and its related illness hypoxic-ischemic encephalopathy (HIE) are major causes of nervous system damage and neurological morbidity in children. Hypoxic preconditioning (HPC) is known to be neuroprotective in cerebral ischemic brain injury. K(ATP) channels are involved
Vasil A Gaisin et al.
Extremophiles : life under extreme conditions, 19(6), 1067-1076 (2015-08-21)
Alkaline hydrotherms of the Baikal rift zone are unique systems to study the diversity of thermophilic bacteria. In this study, we present data on the phototrophic bacterial community of cyanobacterial mats from the alkaline Alla hot spring. Using a clonal
Ralf Miethchen et al.
Carbohydrate research, 340(4), 741-748 (2005-02-22)
l-1-Deoxy-1-fluoro-6-O-methyl-myo-inositol was epimerized by chloral/DCC in boiling 1,2-dichloroethane yielding D-1-O-cyclohexylcarbamoyl-2-deoxy-2-fluoro-3-O-methyl-5,6-O-[(R/S)-2,2,2-trichloroethylidene]-chiro-inositol. The latter and l-4-O-benzyl-3-O-cyclohexylcarbamoyl-5-O-methyl-1,2-O-(2,2,2-trichloroethylidene)-muco-inositol, l-4-O-benzyl-3-O-cyclohexylcarbamoyl-1,2-O-ethylidene-5-O-methyl-muco-inositol, d-1-O-cyclohexylcarbamoyl-2-deoxy-5,6-O-ethylidene-2-fluoro-3-O-methyl-chiro-inositol, as well as D-5-O-benzyl-4-O-cyclohexylcarbamoyl-3-deoxy-3-(N,N'-dicyclohexylureido)-6-O-methyl-1,2-O-(2,2,2-trichloroethylidene)-chiro-inositol were deprotected with boiling 57% aq hydrogen iodide. Ether, urethane and ethylidene acetal functions were simultaneously cleaved by the reagent
Kristen A Neville et al.
Clinical endocrinology, 82(5), 657-662 (2015-01-20)
It is unclear whether the rate of vitamin D deficiency in paediatric cancer survivors is higher than in the background population, and whether this is of pathological significance. 25OHD was measured in a previously studied group of 208 survivors (n
Kazumasa Wakamatsu et al.
Pigment cell & melanoma research, 22(4), 474-486 (2009-06-06)
Pheomelanogenesis is a complex pathway that starts with the oxidation of tyrosine (or DOPA, 3,4-dihydroxyphenylalanine) by tyrosinase in the presence of cysteine, which results in the production of 5-S-cysteinyldopa and its isomers. Beyond that step, relatively little has been clarified
Nora Kuhlmann et al.
Microbiology (Reading, England), 161(9), 1830-1843 (2015-08-25)
The Gram-positive Corynebacterium glutamicum co-metabolizes most carbon sources such as the phosphotransferase system (PTS) sugar glucose and the non-PTS sugar maltose. Maltose is taken up via the ABC-transporter MusEFGK2I, and is further metabolized to glucose phosphate by amylomaltase MalQ, maltodextrin
Andrej Nikoshkov et al.
International journal of oncology, 46(1), 107-112 (2014-10-24)
Cervical cancer is the second most prevalent malignancy among women worldwide, and additional objective diagnostic markers for this disease are needed. Given the link between cancer development and alternative splicing, we aimed to analyze the splicing patterns of the PRDX2
Qiang Huang et al.
PloS one, 10(10), e0141395-e0141395 (2015-10-30)
Patients have responded well to the multi-targeted tyrosine kinase inhibitor (TKI) Sunitinib in the clinic. But the severe toxic side effects associated with Sunitinib limit its therapeutic index. To improve the therapeutic index of Sunitinib, a prodrug strategy was employed
Vanitha Kunalan et al.
Analytical chemistry, 84(13), 5744-5752 (2012-06-05)
The synthesis of methylamphetamine hydrochloride from l-ephedrine or d-pseudoephedrine hydrochloride via reduction with hydriodic acid and red phosphorus was investigated. Eighteen batches of methylamphetamine hydrochloride were synthesized in six replicate batches using three different reaction times. This allowed the investigation
Bin Han et al.
Journal of virological methods, 225, 76-86 (2015-09-24)
The hepatitis C virus (HCV) NS3/4A protease is a key target of efforts to develop direct-acting antiviral inhibitors for treatment of chronic HCV infection. In vitro analyses of the effects of NS3/4A mutations and polymorphisms on protease inhibitor (PI) susceptibility
Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications.
P R Larsen et al.
Endocrine reviews, 2(1), 87-102 (1981-01-01)
Ricardo Alexandre C Lima et al.
Talanta, 147, 226-232 (2015-11-26)
This study proposes the use of digital movies (DMs) in a flow-batch analyzer (FBA) to perform automatic, fast and accurate titrations. The term used for this process is "Digital movie-based on automatic titrations" (DMB-AT). A webcam records the DM during
Marina M Demidova et al.
The American journal of cardiology, 115(4), 417-422 (2015-01-01)
Ventricular fibrillation (VF) during reperfusion (rVF) in ST-segment elevation myocardial infarction (STEMI) is an infrequent but serious event that complicates coronary interventions. The aim of this study was to analyze clinical predictors of rVF in an unselected population of patients
Jacqueline E Milne et al.
The Journal of organic chemistry, 76(22), 9519-9524 (2011-10-13)
A new convenient and scalable synthesis of phenylacetic acids has been developed via the iodide catalyzed reduction of mandelic acids. The procedure relies on in situ generation of hydroiodic acid from catalytic sodium iodide, employing phosphorus acid as the stoichiometric
Dane J Genther et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 70(1), 85-90 (2014-07-16)
Hearing impairment (HI) is highly prevalent in older adults and is associated with social isolation, depression, and risk of dementia. Whether HI is associated with broader downstream outcomes is unclear. We undertook this study to determine whether audiometric HI is
Stefan J Halbherr et al.
Journal of virology, 89(3), 1550-1563 (2014-11-14)
The envelope of influenza A viruses contains two large antigens, hemagglutinin (HA) and neuraminidase (NA). Conventional influenza virus vaccines induce neutralizing antibodies that are predominantly directed to the HA globular head, a domain that is subject to extensive antigenic drift.
Chunyan Zhang et al.
BMC genetics, 16, 33-33 (2015-04-19)
Improving meat quality is a high priority for the pork industry to satisfy consumers' preferences. GWAS have become a state-of-the-art approach to genetically improve economically important traits. However, GWAS focused on pork quality are still relatively rare. Six genomic regions
David Aguilar et al.
Toxicology and applied pharmacology, 276(1), 55-62 (2014-02-01)
Doxorubicin (Dox) is an indispensable chemotherapeutic agent for the treatment of various forms of neoplasia such as lung, breast, ovarian, and bladder cancers. Cardiotoxicity is a major concern for patients receiving Dox therapy. Previous work from our laboratory indicated that
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