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Showing 1-30 of 164 results for "258024" within Papers
Effect of an extruded pea or rice diet on postprandial insulin and cardiovascular responses in dogs.
J L Adolphe et al.
Journal of animal physiology and animal nutrition, 99(4), 767-776 (2014-12-06)
Peas are increasing in popularity as a source of carbohydrate, protein and fibre in extruded canine diets. The aim of this study was to test the health effects of two canine diets with identical macronutrient profiles, but containing either yellow
Matthew Page et al.
Pharmacology, 96(3-4), 131-136 (2015-08-01)
To this date, the only available drugs for treating Alzheimer's disease are cognitive enhancers, which may improve the cognitive function of patients for a few years while the disease continues to progress. As such, there are intense investigations to develop
Christopher P Locher et al.
Antimicrobial agents and chemotherapy, 59(3), 1455-1465 (2014-12-24)
New drugs to treat drug-resistant tuberculosis are urgently needed. Extensively drug-resistant and probably the totally drug-resistant tuberculosis strains are resistant to fluoroquinolones like moxifloxacin, which target gyrase A, and most people infected with these strains die within a year. In
Rajaletchumy Veloo Kutty et al.
Biomaterials, 63, 58-69 (2015-06-18)
In this study we examined the efficacy of our micellar system in xenograft models of triple negative breast cancers and explored the effect of the micelles on post-treatment tumours in order to elucidate the mechanism underlying the nanomedicine treatment in
Suresh B Lakshminarayana et al.
Antimicrobial agents and chemotherapy, 59(2), 1200-1210 (2014-12-10)
Limited information is available on the pharmacokinetic (PK) and pharmacodynamic (PD) parameters driving the efficacy of antimalarial drugs. Our objective in this study was to determine dose-response relationships of a panel of related spiroindolone analogs and identify the PK-PD index
Shaban Y Shaban et al.
Dalton transactions (Cambridge, England : 2003), 44(31), 14110-14121 (2015-07-15)
A series of copper(ii) complexes, viz. [Tp(MeMe)Cu(Cl)(H2O)] (), [Tp(MeMe)Cu(OAc)(H2O)] (), [Tp(MeMe)Cu(NO3)] () and [Tp(MeMe)Cu(ClO4)] () containing tris(3,5-dimethylpyrazolyl)borate (KTp(MeMe)), have been synthesized and fully characterized. The substitution reaction of with thiourea was studied under pseudo-first-order conditions as a function of concentration
Mahmoud S Sharaf et al.
Free radical biology & medicine, 84, 142-153 (2015-04-07)
Zinc and calcium have highly interwoven functions that are essential for cellular homeostasis. Here we first present a novel real-time flow cytometric technique to measure mitochondrial redox state and show it is modulated by zinc and calcium, individually and combined.
Bernardino Alcázar Navarrete et al.
Clinical drug investigation, 35(9), 569-574 (2015-08-15)
To date, no evidence exists in the literature as to the effects of inhaled corticosteroids (ICs) on salivary composition in patients with bronchial asthma. The aim of this study was to assess the effect of ICs on salival composition. Adult
William G Christen et al.
Ophthalmic epidemiology, 22(2), 85-93 (2015-03-18)
Prospective data to examine the association of homocysteine with age-related macular degeneration (AMD) are limited. We examined the prospective relation of plasma homocysteine level and AMD in a large cohort of apparently healthy women. We evaluated the relationship between baseline
Partha Pratim Roy et al.
Bioorganic chemistry, 56, 1-7 (2014-06-03)
The objective of the present work was tantamount to explain the antiperoxidative potential and structural requirements of twenty-eight structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation. Both experimental and computational approaches were taken to the work. The experiments were
The two faces of α- and γ-tocopherols: an in vitro and ex vivo investigation into VLDL, LDL and HDL oxidation.
Nadeem N, Woodside JV, et al.
The Journal of Nutritional Biochemistry (2011)
Jana Cela et al.
Plant & cell physiology, 52(8), 1389-1400 (2011-07-02)
Tocopherols are antioxidants found in chloroplasts of leaves, and it is a matter of current debate whether or not they can affect signaling and gene expression in plant cells. For insight into the possible effects of altered tocopherol composition in
Juliana Bidone et al.
BioMed research international, 2015, 238010-238010 (2015-06-24)
This study investigated the inhibitory effects of Achyrocline satureioides extract (ASE) incorporated into a topical nanoemulsion on Herpes Simplex Virus type 1 (HSV-1/KOS strain) replication, as well as the distribution of the main ASE flavonoids (quercetin, luteolin, and 3-O-methylquercetin) in
Yun Wang et al.
The Journal of nutritional biochemistry, 23(6), 602-608 (2011-07-19)
Eotaxin-3 (CCL-26), a potent chemokine for eosinophil recruitment and contributing significantly to the pathogenesis of asthma, is secreted by lung epithelial cells in response to T helper 2 cytokines including interleukin 13 (IL-13). Here we showed that vitamin E forms
C K Parr et al.
Journal of animal science, 93(5), 2165-2173 (2015-05-29)
An experiment was conducted to evaluate effects of 2 high-protein canola meals (canola meal A [CMA]: 45.69% CP and canola meal B [CMB]: 46.97% CP) and a conventional canola meal (CM-CV: 35.10% CP) on growth performance, organ weights, bone ash
Jesús Crespo-Sanjuán et al.
Laboratory medicine, 46(2), 123-135 (2015-04-29)
To detect whether signs of oxidative stress appear at early stages of colorectal adenocarcinoma (CRC), particularly in the polyp stage. We also aimed to evaluate the specific entities myeloperoxidase (MPO) and oxidized low-density lipoprotein (oxLDL) as novel markers of oxidation
Ratchanee Kongkachuichai et al.
Food chemistry, 173, 838-846 (2014-12-04)
Evidence from epidemiological studies has strongly suggested that diets rich in fruits and vegetables play a vital role in disease prevention. The aim of this study was to determine nutrient and antioxidant content for 15 varieties of indigenous vegetables and
Jay J Cao et al.
Calcified tissue international, 97(2), 145-155 (2015-04-24)
This study investigated whether exercise or antioxidant supplementation with vitamin C and E during exercise affects bone structure and markers of bone metabolism in obese rat. Sprague-Dawley rats, 6-week old, were fed a normal-fat diet (NF, 10 % kcal as
R Preston Mason et al.
Biochimica et biophysica acta, 1848(2), 502-509 (2014-12-03)
Lipid oxidation leads to endothelial dysfunction, inflammation, and foam cell formation during atherogenesis. Glucose also contributes to lipid oxidation and promotes pathologic changes in membrane structural organization, including the development of cholesterol crystalline domains. In this study, we tested the
A Dalle Zotte et al.
Poultry science, 94(9), 2114-2123 (2015-07-29)
This study investigated the impact of 2 coccidiosis control systems (vaccine vs anticoccidial) and 2 feeding plans (standard energy vs low energy content, the latter supplemented with threonine and enzymes in the second half of the production cycle) on white
Jared D Hoffman et al.
Mutagenesis, 30(3), 421-430 (2015-02-15)
Isothiocyanates are plant-derived compounds that may be beneficial in the prevention of certain chronic diseases. Yet, by stimulating the production of reactive oxygen species (ROS), isothiocyanates can be genotoxic. Whether antioxidants influence isothiocyanate-induced genotoxicity is unclear, but this situation was
J C González-Vega et al.
Journal of animal science, 93(5), 2255-2264 (2015-05-29)
An experiment was conducted to test the hypothesis that differences in the apparent total tract digestibility (ATTD) and standardized total tract digestibility (STTD) of Ca exist among Ca supplements and that inclusion of microbial phytase increases the ATTD and STTD
Hui Tang et al.
Environmental science and pollution research international, 22(13), 9999-10008 (2015-02-11)
Hydroponic experiments were performed to investigate the ameliorating effects and mitigation mechanisms of selenium and silicon on Cd toxicity in Boehmeria nivea (L.) Gaud. Metal accumulation, chlorophyll content, activities of antioxidant enzymes, and antioxidant contents in ramie were evaluated. The
Srinivasa M Sammeta et al.
Pharmaceutical development and technology, 20(2), 169-175 (2013-11-14)
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches. Different combinations of co-solvents, which were selected on the basis of high-throughput solubility screening, were
Kanagalakshmi Ambothi et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 82, 72-78 (2015-05-20)
The aim of this study was to evaluate the photochemopreventive effects of ferulic acid (FA) against chronic ultraviolet-B (290-320 nm) induced oxidative stress, inflammation and angiogenesis in the skin of Swiss albino mice. Chronic UVB exposure (180 mJ/cm(2) for 30 weeks;
Jian-Zhuang Tan et al.
Journal of the science of food and agriculture, 95(1), 126-135 (2014-04-15)
The effects of dietary l-arginine (Arg) on immunosuppression following infectious bursal disease virus (IBDV) inoculation in broiler chickens were evaluated. The design of this study was a 5 × 2 factorial arrangement (n = 5) with five Arg concentrations (starter:
Bénédicte M J Merle et al.
PloS one, 10(7), e0130816-e0130816 (2015-07-02)
Genetic susceptibility could be modified by environmental factors and may also influence differential responses to treatments for age-related macular degeneration (AMD). We investigated whether genotype could influence response to docosahexaenoic acid (DHA)-supplementation in the occurrence of choroidal new vessels (CNV).
G A Casas et al.
Journal of animal science, 93(7), 3441-3448 (2015-10-07)
The objectives of this experiment were to determine the apparent total tract digestibility (ATTD) and the standardized total tract digestibility (STTD) of P and the effect of microbial phytase on ATTD and STTD of P in full-fat rice bran (FFRB)
Yang Wang et al.
PloS one, 10(8), e0135232-e0135232 (2015-08-15)
Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear. Direct antiviral activity and immunomodulatory
Francisca Rodrigues et al.
Food & function, 6(8), 2854-2860 (2015-07-21)
The present study was aimed to assess the macronutrient composition and the amino acid and vitamin E profiles of Castanea sativa shell from different production regions of Portugal (Minho, Trás-os-Montes and Beira-Alta). The nutritional composition was similar for all samples
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