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Showing 1-30 of 42 results for "323446" within Papers
Muhammad Rizwan Younis et al.
ACS nano, 13(2), 2544-2557 (2019-02-08)
Combination therapy, especially photodynamic/photothermal therapy (PDT/PTT), has shown promising applications in cancer therapy. However, sequential irradiation by two different laser sources and even the utilization of single high-power laser to induce either combined PDT/PTT or individual PTT will be subjected
Maria Sarno et al.
Nanotechnology, 28(21), 214003-214003 (2017-04-07)
A Tafel slope of 40 mV dec
Katrijn De Brucker et al.
Oxidative medicine and cellular longevity, 2013, 704654-704654 (2013-10-01)
This study demonstrates a role for superoxide dismutases (Sods) in governing tolerance of Candida albicans biofilms to amphotericin B (AmB). Coincubation of C. albicans biofilms with AmB and the Sod inhibitors N,N'-diethyldithiocarbamate (DDC) or ammonium tetrathiomolybdate (ATM) resulted in reduced
Doortje W Dekens et al.
Neurochemistry international, 132, 104607-104607 (2019-11-25)
Lipocalin 2 (Lcn2) has been implicated to play a role in various neurodegenerative diseases, and normalizing its overexpression may be of therapeutic potential. Iron chelators were found to reduce Lcn2 levels in certain animal models of CNS injury. Focusing on
Fang Xie et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry (2018-07-15)
Copper 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide complex (CuHQTS) is a copper complex with strong anticancer activity against cisplatin-resistant neuroblastoma and prostate cancer cells in vitro by cell proliferation assay or fluorescent microscopic imaging. This study aimed to evaluate anti-prostate cancer activity of CuHQTS in
Adelita D Mendoza et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 191, 194-202 (2016-09-25)
Zinc is an essential metal that serves as a cofactor in a variety of cellular processes, including meiotic maturation. Cellular control of zinc uptake, availability and efflux is closely linked to meiotic progression in rodent and primate reproduction where large
Youngmoo Jeon et al.
Nanoscale, 11(11), 4837-4845 (2019-03-01)
Molybdenum disulfide (MoS2) is a promising anode material for lithium-ion batteries owing to its high theoretical capacity and low cost. However, it exhibits low electrical conductivity and volume expansion, resulting in poor electrochemical performance. In this work, three-dimensional porous carbon/MoS2
Regina Lohmayer et al.
Analytical chemistry, 87(6), 3388-3395 (2015-02-25)
Molybdenum precipitates preferentially under reducing conditions; therefore, its occurrence in sediment records is used as an indicator of paleoredox conditions. Although thiomolybdates (MoO4-xSx(2-) with x = 1-4) supposedly are necessary intermediates in the process of molybdenum precipitation under anoxic conditions
Cristine L Chisholm et al.
Oncotarget, 7(51), 84439-84452 (2016-11-03)
Cisplatin is an effective breast cancer drug but resistance often develops over prolonged chemotherapy. Therefore, we performed a candidate approach RNAi screen in combination with cisplatin treatment to identify molecular pathways conferring survival advantages. The screen identified ATP7A as a
Yu Lei et al.
Science advances, 6(32), eabc4250-eabc4250 (2020-08-22)
Two-dimensional transition metal dichalcogenides (TMDs) emerged as a promising platform to construct sensitive biosensors. We report an ultrasensitive electrochemical dopamine sensor based on manganese-doped MoS2 synthesized via a scalable two-step approach (with Mn ~2.15 atomic %). Selective dopamine detection is
Heejeong Kim et al.
International journal of molecular sciences, 21(17) (2020-08-29)
Selective autolysosomal degradation of damaged mitochondria, also called mitophagy, is an indispensable process for maintaining integrity and homeostasis of mitochondria. One well-established mechanism mediating selective removal of mitochondria under relatively mild mitochondria-depolarizing stress is PINK1-Parkin-mediated or ubiquitin-dependent mitophagy. However, additional
Xiaoqin Xiong et al.
Scientific reports, 5, 9254-9254 (2015-03-26)
A flexible membrane consisting of MoS2/carbon nanofibers has been fabricated by a simple electrospinning method. MoS2 nanosheets are uniformly encapsulated in the inter-connected carbon nanofibers with diameters of ~150 nm. When evaluated as a binder-free electrode for sodium-ion batteries, the as-obtained
Jonathan C Rupp et al.
Virology journal, 14(1), 11-11 (2017-01-25)
The essential role of copper in eukaryotic cellular physiology is known, but has not been recognized as important in the context of influenza A virus infection. In this study, we investigated the effect of cellular copper on influenza A virus
Caroline I Davis et al.
Metallomics : integrated biometal science, 12(12), 1995-2008 (2020-11-05)
Hepatocellular carcinoma (HCC), the most common primary liver cancer, of which ∼800 000 new cases will be diagnosed worldwide this year, portends a five-year survival rate of merely 17% in patients with unresectable disease. This dismal prognosis is due, at least
Lang, J-P. Tatsumi, K.
Inorganic Chemistry, 37, 6308-6308 (1998)
Satoru Yamasaki et al.
The Journal of cell biology, 177(4), 637-645 (2007-05-16)
Zinc is an essential trace element required for enzymatic activity and for maintaining the conformation of many transcription factors; thus, zinc homeostasis is tightly regulated. Although zinc affects several signaling molecules and may act as a neurotransmitter, it remains unknown
George J Brewer
Current cancer drug targets, 5(3), 195-202 (2005-05-17)
Tetrathiomolybdate (TM) is a novel anticopper agent under development for use in Wilson's disease. It acts by forming a stable tripartite complex with serum albumin and copper, rendering the complexed copper unavailable for cellular uptake. TM is a very potent
Devarajulu Sureshkumar et al.
The Journal of organic chemistry, 72(6), 2106-2117 (2007-02-24)
A comprehensive study of a general and effective one-step procedure for the synthesis of beta-sulfonamidodisulfides directly from N-tosyl aziridines in a regio- and stereospecific manner under neutral conditions without the use of any Lewis acid or base has been reported.
Zhe Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 34(4), 1635-1644 (2018-01-02)
Wear occurs between two rubbing surfaces. Severe wear due to seizure under high pressure leads to catastrophic failures of mechanical systems and raises wide concerns. In this paper, a kind of synthetic oil-soluble ultrathin MoS
Alma Mejri et al.
Analytica chimica acta, 1137, 19-27 (2020-11-07)
A non-enzymatic sensor based on a curcumin modified pencil graphite electrode, loaded with molybdenum disulfide nanosheets decorated gold foam, was constructed. Herein, the electrochemical deposition strategy was adopted throughout the sensing platform design stepwise. The electroactivity of the pencil electrode
Peng-Yang Hsu et al.
Journal of dermatological science, 92(1), 30-37 (2018-08-22)
Copper is an essential metal for maintenance of many biological functions; however, excessive amount can induce inflammation and oxidative stress. Tetrathiomolybdate (TM) is a copper chelator for treatment of Wilson's disease, and decreased the severity of autoimmune arthritis in mice.
Changyi Ji et al.
Cellular and molecular neurobiology, 38(4), 941-954 (2017-11-28)
Iron efflux in mammalian cells is mediated by the ferrous iron exporter ferroportin (Fpn); Fpn plasma membrane localization and function are supported by a multicopper ferroxidase and/or the soluble amyloid precursor protein (sAPP). Fpn and APP are ubiquitously expressed in
Yu Zhou et al.
Small (Weinheim an der Bergstrasse, Germany), 15(19), e1900078-e1900078 (2019-04-09)
Using the MoS2 -WTe2 heterostructure as a model system combined with electrochemical microreactors and density function theory calculations, it is shown that heterostructured contacts enhance the hydrogen evolution reaction (HER) activity of monolayer MoS2 . Two possible mechanisms are suggested
Fangying Lv et al.
Journal of chromatography. A, 1525, 42-50 (2017-10-24)
In this work, the molybdenum disulfide/reduced graphene oxide (MoS
Anh D Nguyen et al.
Chemistry, an Asian journal, 15(19), 2996-3002 (2020-08-14)
Amorphous molybdenum sulfide (MoSx ) is a promising alternative to Pt catalyst for the H2 evolution in water. However, it is suffered of an electrochemical corrosion. In this report, we present a strategy to tack this issue by embedding the
Kyu Kwang Kim et al.
BMC cancer, 12, 147-147 (2012-04-17)
Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To expand these findings in the present study we explore TM efficacy
Pengfei Cao et al.
Scientific reports, 7(1), 16048-16048 (2017-11-24)
Amorphous molybdenum sulfide/carbon black (MoS
Jarmila Navrátilová et al.
Journal of cellular and molecular medicine, 21(9), 1859-1869 (2017-03-01)
Neuroblastoma is the most common extracranial solid tumour of infancy. Pathological activation of glucose consumption, glycolysis and glycolysis-activating Akt kinase occur frequently in neuroblastoma cells, and these changes correlate with poor prognosis of patients. Therefore, several inhibitors of glucose utilization
Ye-Jin Kim et al.
Cancer research, 80(7), 1387-1400 (2020-02-02)
The principal unmet need in BRAFV600E-positive melanoma is lack of an adequate therapeutic strategy capable of overcoming resistance to clinically approved targeted therapies against oncogenic BRAF and/or the downstream MEK1/2 kinases. We previously discovered that copper (Cu) is required for
Alison M Kim et al.
Nature chemical biology, 6(9), 674-681 (2010-08-10)
Cellular metal ion fluxes are known in alkali and alkaline earth metals but are not well documented in transition metals. Here we describe major changes in the zinc physiology of the mammalian oocyte as it matures and initiates embryonic development.
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