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Showing 1-30 of 30 results for "328014" within Papers
M Ogata et al.
International archives of occupational and environmental health, 58(2), 121-129 (1986-01-01)
A new method for the direct determination of hippuric acid (HA) and o-, m- and p-methylhippuric acids (MHAs) in the urine, metabolites of toluene and o-, m- and p-xylenes by high performance liquid chromatography (HPLC) is described. A stainless-steel column
Daniel B Lunn et al.
Journal of chromatography. A, 1530, 112-119 (2017-11-22)
The study of metabolites in biological samples is of high interest for a wide range of biological and pharmaceutical applications. Reversed phase liquid chromatography is a common technique used for the separation of metabolites, but it provides little retention for
Joon Hyuk Suh et al.
Journal of separation science, 38(24), 4276-4285 (2015-10-27)
For the first time, electromembrane extraction combined with liquid chromatography and tandem mass spectrometry was applied for the determination of urinary benzene, toluene, ethylbenzene, and xylene metabolites. S-Phenylmercapturic acid, hippuric acid, phenylglyoxylic acid, and methylhippuric acid isomers were extracted from
I Lundberg et al.
Scandinavian journal of work, environment & health, 12(2), 149-153 (1986-04-01)
Different calculations of methyl hippuric acid excretion in urine were correlated to the time-weighted average (TWA) of the xylene exposure of a complete workday for 40 paint industry workers exposed to 12 different solvents. The 8-h TWA xylene exposure varied
M Ogata et al.
International archives of occupational and environmental health, 61(1-2), 131-140 (1988-01-01)
An attempt was made to establish a method for the direct determination of urinary concentrations of creatinine, hippuric acid, methylhippuric acid and mandelic acid by automated high performance liquid chromatography (HPLC). Urine was diluted with distilled water or mobile phase
A Astier
Journal of chromatography, 573(2), 318-322 (1992-01-17)
A high-performance liquid chromatographic method is described for the simultaneous determination of six urinary metabolites of several aromatic chemicals: phenol (from benzene), hippuric acid (from toluene), 3-methylhippuric acid (from xylene), mandelic and phenylglyoxylic acid (from styrene) and 4-nitrophenol (from nitrobenzene).
M J Miller et al.
International archives of occupational and environmental health, 72(2), 89-97 (1999-04-10)
Solvent exposures commonly involve mixtures of substances or mixtures of isomers of a single solvent. These may be metabolised through common pathways, resulting in the potential for metabolic interactions. These may then lead to accumulation of solvent or metabolic intermediates
High-performance liquid chromatographic separation of urinary hippuric and o-, m- and p-methylhippuric acids with a beta-cyclodextrin-bonded column.
H Matsui et al.
Journal of chromatography, 496(1), 189-193 (1989-11-10)
Determination of methylhippuric acid in human urine by high-performance liquid chromatography and by isotachophoresis.
J Sollenberg et al.
Journal of chromatography, 343(2), 419-423 (1985-10-11)
[A method for storage of urine samples in the biological monitoring of organic solvents].
R S Wang et al.
Sangyo igaku. Japanese journal of industrial health, 34(1), 42-43 (1992-01-01)
R Tardif et al.
Occupational and environmental medicine, 51(3), 187-191 (1994-03-01)
This study was undertaken to determine whether previous subacute treatment with ethanol could modify the kinetics of m-xylene in humans. A group of six volunteers was exposed twice to either 100 or 400 ppm of m-xylene during two hours (between
Marie Meyer-Monath et al.
Talanta, 138, 231-239 (2015-04-13)
Meconium is the first fecal excretion of newborns. This complex accumulative matrix allows assessing the exposure of the fetus to xenobiotics during the last 6 months of pregnancy. To determine the eventual effect of fetal exposure to micropollutants in this
Y Takeuchi et al.
Sangyo igaku. Japanese journal of industrial health, 28(6), 455-461 (1986-11-01)
A study was made on the effect of detection wavelength and separation mode of HPLC on determination of urinary hippuric acid (HA) and three isomers of methylhippuric acid (MHA). The interference of other constituents of urine in the determination was
Estimation of solvent concentrations in ambient air from urinary metabolite levels of workers exposed to solvents.
M Ogata
Industrial health, 22(4), 319-324 (1984-01-01)
O Inoue et al.
International archives of occupational and environmental health, 64(7), 533-539 (1993-01-01)
The correlation between exposure to three xylene isomers and resulting urinary excretion of corresponding methylhippuric acid (MHA) isomers was studied among 175 Chinese workers of both sexes who had been predominantly exposed to xylenes (exposure to xylenes accounting for 70%
J Liira et al.
Xenobiotica; the fate of foreign compounds in biological systems, 21(1), 53-63 (1991-01-01)
1. Rats were exposed to m-xylene (300 ppm) and methyl ethyl ketone (MEK, 600 ppm) vapour, separately and in combination. 2. Repeated exposures to m-xylene enhanced liver drug-metabolizing capacity, whereas MEK showed no effects. After mixed exposure the cytochrome P-450-dependent
Determination of methylhippuric acids in urine by gas chromatography.
K Engström et al.
IARC scientific publications, (85)(85), 313-318 (1988-01-01)
R Tardif et al.
Journal of analytical toxicology, 13(6), 313-316 (1989-11-01)
A high-performance liquid chromatographic assay for the simultaneous analysis of hippuric and methylhippuric acids in urine is described. Compounds are first extracted from acidified urines after addition of o-methylbenzoylalanine (internal standard), using methyl-t-butyl ether. The organic phase is evaporated under
Marie Meyer-Monath et al.
Analytical and bioanalytical chemistry, 406(30), 7785-7797 (2014-11-10)
Meconium is the earliest stool of newborns. It is a complex matrix that reflects the degree of fetal exposure to environmental pollutants. To investigate exposure to xenobiotics, an analytical method was developed to identify and quantify some pesticides and their
Simultaneous determination of hippuric acid, o-, m-, and p-methylhippuric acid, phenylglyoxylic acid, and mandelic acid by HPLC.
O Inoue et al.
Bulletin of environmental contamination and toxicology, 47(2), 204-210 (1991-08-01)
[Simultaneous determination of urinary hippuric acid and o-, m-, p-methylhippuric acids with liquid chromatography].
C Lacroix et al.
Journal of chromatography, 382, 275-279 (1986-10-31)
C Burrini
La Medicina del lavoro, 89(5), 404-411 (1999-03-05)
A high-performance liquid chromatographic method is described for the simultaneous determination of six metabolites of aromatic hydrocarbons: hippuric acid (HA) from toluene; o-, m-, p-methylhippuric acids (o-, m-, p-MHA) from xylene; mandelic acid (MA) and phenylglyoxylic acid (PGA) from styrene
D de Carvalho et al.
International archives of occupational and environmental health, 63(1), 33-37 (1991-01-01)
The industrial solvents, toluene and xylene, have physicochemical properties that can be hazardous to the workers exposed. Since hippuric acid and m-methyl-hippuric acid represent the products of toluene and xylene biotransformation in urine, they are used as biological markers in
K J Lee et al.
Electrophoresis, 15(1), 98-102 (1994-01-01)
The factors affecting micellar electrokinetic capillary chromatographic separation of hippuric and o-, m-, p-methylhippuric acid were investigated by changing the species of micelles, and adding urea to the micellar solution. The analysis of hippurates in human urine is demonstrated under
[Determination of hippuric and methylhippuric acids with high pressure liquid chromatography: comparison between chromatographic and colorimetric methods].
M Buratti et al.
La Medicina del lavoro, 79(6), 489-499 (1988-11-01)
T Kaneko et al.
Pharmacological research, 42(5), 465-470 (2000-10-12)
A physiologically based pharmacokinetic model of the transfer of organic solvents in rat bodies was developed. The model has six compartments, i.e. lungs, vessel-rich tissue, muscles, fat tissue, tail, and liver, each being interconnected by the blood flow system. The
L Campbell et al.
British journal of industrial medicine, 45(2), 127-132 (1988-02-01)
In a series of experiments to investigate interactions between industrial solvents and common medications the interaction between m-xylene and aspirin was studied. As both these substances are metabolised and excreted as glycine conjugates there would possibly be competition for this
Hongxuan Kuang et al.
Ecotoxicology and environmental safety, 210, 111864-111864 (2021-01-08)
Volatile organic compounds (VOCs) are important and ubiquitous air pollutants, which may lead to a significant increase in the prevalence of respiratory diseases. To investigate the relationships between VOCs exposure and childhood asthma, 252 asthmatic children and 69 healthy children
[Quantitative determination of urinary hippuric acid and o-, m- and p-methyl hippuric acids by high performance liquid chromatography].
M Ogata et al.
Sangyo igaku. Japanese journal of industrial health, 28(2), 120-121 (1986-03-01)
P Kongtip et al.
Journal of chromatography. B, Biomedical sciences and applications, 751(1), 199-203 (2001-03-10)
A modified method for the simultaneous determination of hippuric acid (HA) and o-, m- and p-methylhippuric acids (o-, m- and p-MHAs) in urine is described. These metabolites were extracted, derivatized into their methyl ester derivatives and analyzed using a gas
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