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Showing 1-25 of 25 results for "34135" within Papers
Wolfram Föllmann et al.
Journal of toxicology and environmental health. Part A, 79(22-23), 1015-1025 (2016-12-08)
Contamination of grains with mycotoxins results in a dietary background exposure of the general population. In occupational settings such as during processing of raw materials as in milling, an additional mycotoxin exposure by inhalation is possible. Biomonitoring is an integrative
Silvia W Gratz et al.
Journal of agricultural and food chemistry, 68(1), 351-357 (2019-12-13)
Cereal foods are commonly contaminated with multiple mycotoxins resulting in frequent human mycotoxin exposure. Children are at risk of high-level exposure because of their high cereal intake relative to body weight. Hence, this study aims to assess multimycotoxin exposure in
Application of an HPLC?MS/MS method for mycotoxin analysis in commercial baby foods
Rubert J, et al.
Food Chemistry, 133, 176-183 (2012)
Sandra Debevere et al.
Toxins, 12(6) (2020-06-25)
Ruminal microbiota of cattle are not able to detoxify all mycotoxins. In addition, detoxification can be hampered by adverse ruminal conditions (e.g., low ruminal pH). Hence, in the cattle husbandry, mycotoxin binders and modifiers could be used to prevent animal
Marianne Lauwers et al.
Toxins, 11(3) (2019-03-22)
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, and feces of pigs, and plasma and excreta of broiler chickens using liquid chromatography⁻tandem mass spectrometry. The targeted mycotoxins belong to the regulated groups, i.e.
Barbara Novak et al.
Toxins, 10(4) (2018-04-12)
Deoxynivalenol (DON) is one of the most prevalent mycotoxins, contaminating cereals and cereal-derived products. Its derivative deepoxy-deoxynivalenol (DOM-1) is produced by certain bacteria, which either occur naturally or are supplemented in feed additive. DON-induced impairments in protein synthesis are particularly
Elisabeth Mayer et al.
Mycotoxin research, 33(4), 297-308 (2017-07-26)
Deoxynivalenol (DON), a trichothecene produced by various Fusarium species, is one of the most prevalent food- and feed-associated mycotoxins. The effects of DON and deepoxy-deoxynivalenol (DOM-1) were assessed in five different cell lines from different tissues and species starting from
Eleni Vatzia et al.
Frontiers in immunology, 11, 2009-2009 (2020-09-10)
Deoxynivalenol (DON) is a Fusarium mycotoxin that frequently contaminates the feed of farm animals. Pigs with their monogastric digestive system are in particular sensitive to DON-contaminated feed. At high concentrations, DON causes acute toxic effects, whereas lower concentrations lead to
Ruqin Lin et al.
Biochemical pharmacology, 175, 113868-113868 (2020-02-24)
Deoxynivalenol (DON) is the most common mycotoxin in grains, and DON exposure causes gastrointestinal inflammation and systemic immunosuppression. The immunosuppression caused by DON has raised serious concerns about whether it is safe to use probiotics in immunocompromised hosts. Gut microbiota
Tolke Jensen et al.
Mycotoxin research, 36(2), 127-136 (2019-11-11)
Fusarium mycotoxins and their derivatives are frequently detected in freshly harvested forage maize. This study assessed the time course effects during ensiling of forage maize on the fate of Fusarium mycotoxins, using laboratory-scale silos and artificially contaminated raw material. A
Amin Sayyari et al.
Toxins, 10(12) (2018-12-07)
Deoxynivalenol (DON) contamination of feed may result in reduced growth, feed refusal, immunosuppression, and health problems in swine. Piglets can be exposed to DON via placenta before birth and via milk during lactation. The extent of early-life exposure of piglets
N De Zutter et al.
Scientific reports, 6, 38640-38640 (2016-12-09)
Biotransformation of mycotoxins in animals comprises phase I and phase II metabolisation reactions. For the trichothecene deoxynivalenol (DON), several phase II biotransformation reactions have been described resulting in DON-glutathiones, DON-glucuronides and DON-sulfates made by glutathione-S-transferases, uridine-diphosphoglucuronyl transferases and sulfotransferases, respectively.
Yan Zhu et al.
Journal of chromatography. A, 1556, 81-87 (2018-05-08)
Deoxynivalenol (DON) is a type B trichothecene mycotoxin that is commonly detected in grains infested with Fusarium species. The maximum tolerated levels of DON in the majority of world's countries are restricted to 0.75 mg kg-1 within the human food chain and
Alexandra Springler et al.
Mycotoxin research, 33(1), 25-37 (2016-11-07)
The mycotoxin deoxynivalenol (DON) contaminates agricultural commodities worldwide, posing health threats to humans and animals. Associated with DON are derivatives, such as deepoxy-deoxynivalenol (DOM-1), produced by enzymatic transformation of certain intestinal bacteria, which are naturally occurring or applied as feed
Xiaojuan Gao et al.
Toxins, 12(2) (2020-01-30)
Deoxynivalenol (DON) is a highly abundant mycotoxin that exerts many adverse effects on humans and animals. Much effort has been made to control DON in the past, and bio-transformation has emerged as the most promising method. However, useful and effective
Arnau Vidal et al.
Food research international (Ottawa, Ont.), 101, 139-147 (2017-09-25)
Deoxynivalenol (DON) is one of the most frequently occurring mycotoxins in wheat crops worldwide and poses a risk to human and animal health due to its wide range of adverse effects. Deoxynivalenol-3-glucoside (DON-3-glucoside) is a DON plant conjugate that is
Sandra Debevere et al.
Toxins, 12(2) (2020-02-09)
Ruminants are generally considered to be less susceptible to the effects of mycotoxins than monogastric animals as the rumen microbiota are capable of detoxifying some of these toxins. Despite this potential degradation, mycotoxin-associated subclinical health problems are seen in dairy
Larissa T Franco et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 128, 21-34 (2019-03-31)
This study aimed to assess the exposure of Brazilian residents (N = 86) from rural areas to multiple mycotoxins and characterize the associated risk in two sampling periods (SP) (April-May and December/2016). Mycotoxins in food and urine samples were determined by liquid
Arnau Vidal et al.
Toxins, 12(2) (2020-02-28)
Deoxynivalenol is one of the most ubiquitous mycotoxins in the Western diet through its presence in cereals and cereal products. A vast amount of studies indicate the worrying level of exposure to this toxin, while even high percentages of the
Nathan Broekaert et al.
Archives of toxicology, 91(2), 699-712 (2016-04-22)
Crossover animal trials were performed with intravenous and oral administration of deoxynivalenol-3-β-D-glucoside (DON3G) and deoxynivalenol (DON) to broiler chickens and pigs. Systemic plasma concentrations of DON, DON3G and de-epoxy-DON were quantified using liquid chromatography-tandem mass spectrometry. Liquid chromatography coupled to
Bonnie Valgaeren et al.
Archives of toxicology, 93(2), 293-310 (2018-12-12)
A clinical case in Belgium demonstrated that feeding a feed concentrate containing considerable levels of deoxynivalenol (DON, 1.13 mg/kg feed) induced severe liver failure in 2- to 3-month-old beef calves. Symptoms disappeared by replacing the highly contaminated corn and by stimulating
Manami Matsumoto et al.
Bioorganic & medicinal chemistry letters, 29(8), 982-985 (2019-02-25)
The novel trichothecene 12-deoxytrichodermin (3) was isolated from the fungus Trichoderma sp. 1212-03, and included with other known natural trichothecenes in a structure-activity relationship investigation against a human colon cancer cell line (COLO201) and filamentous fungus Cochliobolus miyabeanus. This revealed
Noshin Daud et al.
Toxins, 12(10) (2020-10-18)
Mycotoxins are important food contaminants that commonly co-occur with modified mycotoxins such as mycotoxin-glucosides in contaminated cereal grains. These masked mycotoxins are less toxic, but their breakdown and release of unconjugated mycotoxins has been shown by mixed gut microbiota of
Sample clean-up methods, immunoaffinity chromatography and solid phase extraction, for determination of deoxynivalenol and deepoxy deoxynivalenol in swine serum
He J, et al.
Mycotoxin Research, 25, 89-94 (2009)
Arnau Vidal et al.
Food chemistry, 178, 276-286 (2015-02-24)
The stability of deoxynivalenol (DON), deoxynivalenol-3-glucoside (DON-3-glucoside), 3-acetyldeoxynivalenol (3-ADON), 15-acetyldeoxynivalenol (15-ADON), de-epoxy-deoxynivalenol (DOM-1) and ochratoxin A (OTA) during thermal processing has been studied. Baking temperature, time and initial mycotoxin concentration in the raw materials were assayed as factors. An improved
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