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Showing 1-30 of 713 results for "342483" within Papers
Sunaro C Ngourn et al.
Langmuir : the ACS journal of surfaces and colloids, 28(33), 12151-12158 (2012-07-27)
A quartz crystal microbalance (QCM) sensor was developed for the quantitation of calcium phosphate mineralization and the assessment of DNA as a template molecule. Inherent advantages of QCM, such as nanogram sensitivity, temporal resolution, surface-based measurements, and flow capabilities, were
Samuel Adler et al.
Gastrointestinal endoscopy, 76(6), 1170-1174 (2012-10-03)
Colon capsule endoscopy (CCE) is a noninvasive technique for the detection of colorectal lesions. However, for CCE to be offered as an out-of-clinic procedure, the system needs to automatically alert the patient when to ingest the laxative (booster). We tested
Mst Shahnaj Parvin et al.
BMC research notes, 8, 412-412 (2015-09-06)
The various parts of Cresecentia cujete have some important biological activities. In folklore medicine leaves are used to treat hematomas, tumors and hypertension. Fruit decoction is used to treat diarrhea, stomachaches, cold, bronchitis, cough, asthma, and urethritis. The present study
Moon-Jung Kim et al.
Biochemical and biophysical research communications, 461(4), 648-652 (2015-04-29)
Thioredoxin (Trx) is a major thiol-disulfide reductase that plays a role in many biological processes, including DNA replication and redox signaling. Although selenocysteine (Sec)-containing Trxs have been identified in certain bacteria, their enzymatic properties have not been characterized. In this
Fei Zhou et al.
Molecular medicine reports, 11(3), 1639-1646 (2014-11-19)
Aromatase inhibitors (AIs) are widely used in the treatment of hormone‑dependent breast cancer and as a result, aromatase inhibitor‑associated bone loss (AIBL) has become a major concern amongst patients receiving AI treatment. Modified Shu‑Gan‑Liang‑Xue decoction (mSGLXD), a clinical prescription, has
Stephanie J Bissel et al.
Journal of neuropathology and experimental neurology, 74(8), 767-777 (2015-06-27)
Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is associated with seizures and destructive periventricular white matter lesions. Despite unremarkable cerebrospinal fluid (CSF), HPeV3 RNA can
Aurélien Chollet et al.
Journal of structural biology, 190(3), 328-337 (2015-04-22)
InhA is an enoyl-ACP reductase of Mycobacterium tuberculosis implicated in the biosynthesis of mycolic acids, essential constituents of the mycobacterial cell wall. To date, this enzyme is considered as a promising target for the discovery of novel antitubercular drugs. In
Heng Kang et al.
Molecular plant-microbe interactions : MPMI, 28(5), 534-545 (2015-03-12)
The calcium/calmodulin-dependent protein kinase CCaMK forms a complex with its phosphorylation target CIP73 (CCaMK-interacting protein of 73 kDa). In this work, a homolog of the animal HSC/HSP70 interacting protein (HIP) was identified as an interacting partner of CIP73 in Lotus
Cameron P Brewer et al.
International journal of sport nutrition and exercise metabolism, 23(2), 187-194 (2012-11-02)
Research into supplementation with sodium phosphate has not investigated the effects of a repeated supplementation phase. Therefore, this study examined the potential additive effects of repeated sodium phosphate (SP) supplementation on cycling time-trial performance and peak oxygen uptake (VO2peak). Trained
Colonoscopy preperations.
The Medical letter on drugs and therapeutics, 55(1408), 6-6 (2013-01-26)
Mohamad Alaa Terkawi et al.
Malaria journal, 13, 426-426 (2014-11-07)
The design and development of an effective malaria vaccine against the pre-erythrocytic and erythrocytic-stages of infection present a great challenge. In the present study, protective efficacy of oligomannose-coated liposome (OML)-entrapped merozoite and sporozoite antigens against Plasmodium berghei challenge infection in
A K Krug et al.
Cell death & disease, 5, e1222-e1222 (2014-05-09)
Assessment of the network of toxicity pathways by Omics technologies and bioinformatic data processing paves the road toward a new toxicology for the twenty-first century. Especially, the upstream network of responses, taking place in toxicant-treated cells before a point of
P M Kozhin et al.
Bulletin of experimental biology and medicine, 160(1), 57-60 (2015-11-26)
We studied the effects of liposomal pharmaceutical compositions with oxidized dextrans on functional activity of U937 monocyte/macrophage-like cells. Liposomes in the emulsion contained oxidized dextran with a molecular weights of 40 kDa or 70 kDa or isonicotinic acid hydrazide (INAH)
R C S Barcelos et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 38-45 (2014-04-04)
We evaluated the influence of dietary fats on ultraviolet radiation (UVR)-induced oxidative damage in skin of rats. Animals from two consecutive generations born of dams supplemented with fats during pregnancy and breastfeeding were maintained in the same supplementation: soybean-oil (SO
Kevin M Lewis et al.
The Journal of biological chemistry, 290(48), 28665-28674 (2015-09-30)
Calsequestrin 1 is the principal Ca(2+) storage protein of the sarcoplasmic reticulum of skeletal muscle. Its inheritable D244G mutation causes a myopathy with vacuolar aggregates, whereas its M87T "variant" is weakly associated with malignant hyperthermia. We characterized the consequences of
Ferdinando Chiaradonna et al.
Antioxidants & redox signaling, 23(1), 15-29 (2015-04-22)
Vorinostat (suberoylanilide hydroxamic acid; SAHA) is a histone deacetylase inhibitor (HDACi) approved in the clinics for the treatment of T-cell lymphoma and with the potential to be effective also in breast cancer. We investigated the responsiveness to SAHA in human
Valerio Zolla et al.
Aging cell, 14(4), 582-594 (2015-05-20)
The role of lymphatic vessels is to transport fluid, soluble molecules, and immune cells to the draining lymph nodes. Here, we analyze how the aging process affects the functionality of the lymphatic collectors and the dynamics of lymph flow. Ultrastructural
Ina Rink et al.
Journal of immunology (Baltimore, Md. : 1950), 194(11), 5549-5558 (2015-04-29)
The migration of leukocytes in response to chemokine gradients is an important process in the homeostasis of the human immune system and inflammation. In vivo the migration takes place on the surface of the endothelium to which the chemokine gradient
Francesca Paoletti et al.
Biochimica et biophysica acta, 1854(3), 187-197 (2014-12-17)
NGF is the prototype member of the neurotrophin family of proteins that promote the survival and growth of selected neurons in the central and peripheral nervous systems. As for all neurotrophins, NGF is translated as a pre-pro-protein. Over the years
Yijia Jiang et al.
Journal of pharmaceutical sciences, 104(4), 1533-1538 (2015-02-27)
Protein therapeutics differ considerably from small molecule drugs because of the presence of higher order structure (HOS), post-translational modifications, inherent molecular heterogeneity, and unique stability profiles. At early stages of development, multiple molecular candidates are often produced for the same
Xiaolei Ze et al.
mBio, 6(5), e01058-e01015 (2015-10-01)
Ruminococcus bromii is a dominant member of the human gut microbiota that plays a key role in releasing energy from dietary starches that escape digestion by host enzymes via its exceptional activity against particulate "resistant" starches. Genomic analysis of R. bromii
Takehiko Matsuo et al.
Scientific reports, 5, 16842-16842 (2015-11-21)
Poor engraftment of cells after transplantation to the heart is a common and unresolved problem in the cardiac cell therapies. We previously generated cardiovascular cell sheets entirely from pluripotent stem cells with cardiomyocytes, endothelial cells and vascular mural cells. Though
Stuart P Johnston et al.
Journal of food science and technology, 52(7), 4135-4145 (2015-07-04)
The physicochemical and emulsifying properties of legume protein isolates prepared from chickpea (CPI), faba bean (FPI), lentil (LPI) and soy (SPI) were investigated in the presence and absence of genipin. Solubility was highest for CPI (~94 %), followed by LPI (~90 %)
Alistair G Fryatt et al.
Molecular pharmacology, 86(6), 707-715 (2014-10-10)
ATP acts as an extracellular signaling molecule at cell-surface P2X receptors, mediating a variety of important physiologic and pathophysiologic roles. Homomeric P2X1 receptors open on binding ATP and then transition to an ATP-bound closed, desensitized state that requires an agonist-free
Aidong Yuan et al.
PloS one, 10(7), e0133848-e0133848 (2015-07-25)
The axonal cytoskeleton of neurofilament (NF) is a long-lived network of fibrous elements believed to be a stationary structure maintained by a small pool of transported cytoskeletal precursors. Accordingly, it may be predicted that NF content in axons can vary
Ivo A Hendriks et al.
Nature communications, 6, 7289-7289 (2015-06-16)
SUMOylation is a reversible post-translational modification (PTM) regulating all nuclear processes. Identification of SUMOylation sites by mass spectrometry (MS) has been hampered by bulky tryptic fragments, which thus far necessitated the use of mutated SUMO. Here we present a SUMO-specific
Shabarish Thatipamula et al.
Neurobiology of disease, 75, 15-30 (2015-01-03)
Neonatal hypoxic-ischemic (HI) brain injury is a leading cause of mortality and morbidity in infants and children for which there is no promising therapy at present. Previously, we reported induction of neuronal pentraxin 1 (NP1), a novel neuronal protein of
B Li et al.
Mucosal immunology, 7(4), 869-878 (2013-12-05)
Breakdown of the epithelial barrier because of toxins or other insults leads to severe colitis. Interleukin-10 (IL-10) is a critical regulator of this, yet its cellular targets and mechanisms of action are not resolved. We address this here. Mice with
Olof Björnberg et al.
Archives of biochemistry and biophysics, 564, 164-172 (2014-09-27)
Three protein disulfide reductases of the thioredoxin superfamily from the industrially important Gram-positive Lactococcus lactis (LlTrxA, LlTrxD and LlNrdH) are compared to the "classical" thioredoxin from Escherichia coli (EcTrx1). LlTrxA resembles EcTrx1 with a WCGPC active site motif and other
Sandra Murphy et al.
Biology, 4(2), 397-423 (2015-06-13)
In skeletal muscle, the dystrophin-glycoprotein complex forms a membrane-associated assembly of relatively low abundance, making its detailed proteomic characterization in normal versus dystrophic tissues technically challenging. To overcome this analytical problem, we have enriched the muscle membrane fraction by a
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