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388920
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Showing 1-30 of 37 results for "388920" within Papers
Colloids and surfaces. B, Biointerfaces, 49(2), 158-164 (2006-04-22)
A defined change in formulation components affects the physical and chemical characteristics of cationic liposomes (CLs) carriers in many ways. Therefore, a great degree of control can be exercised over the structure by modifying the CLs with various materials, leading
International journal of pharmaceutics, 306(1-2), 71-82 (2005-11-03)
Niosomes have been reported as a possible approach to improve the low corneal penetration and bioavailability characteristics shown by conventional ophthalmic vehicles. Niosomes formed from Span 40 or Span 60 and cholesterol in the molar ratios of 7:4, 7:6 and
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 48(3), 233-238 (1999-12-28)
Properties of oil-in-water emulsions containing non-ionic emulsifiers were evaluated in relation to nature of the dispersed phase, emulsifier composition and processing parameters. Particle size of mineral oil (hydrocarbons)-in-water emulsions was independent of the HLB of an optimized emulsifier blend, whereas
Journal of liposome research, 29(2), 171-182 (2018-09-18)
Bilosomes were developed in order to investigate their efficacy as nanocarriers for transdermal delivery of Tizanidine HCl (TZN), a skeletal muscle relaxant with low oral bioavailability. Full factorial experimental design consisting of 27 combinations was generated to study the effects
Colloids and surfaces. B, Biointerfaces, 152, 269-276 (2017-01-26)
Self-assembled surfactant aggregates, such as micelles and vesicles, have been investigated for their application as drug carriers in the treatment of various diseases. However, the characteristics that decide which aggregate is the best drug carrier for each disease have not
Bioresource technology, 191, 300-305 (2015-05-26)
Bio-based fuels are becoming more and more important due to the depleting fossil resources. The production of biodiesel from algae oil is challenging compared to terrestrial vegetable oils, as algae oil consists of polar fatty acids, such as phospholipids and
Drug delivery, 14(2), 75-85 (2007-03-17)
This study involves development of amphiphilic gels consisting solely of nonionic surfactants bearing cyclosporine and characterized for microstructure, gelation temperature, and in vitro drug release into dermis. The formulation is nonirritant and suitable for topical application. Gels consisting of cyclosporine
Drug delivery, 12(2), 75-82 (2005-04-13)
A proniosomal gel for transdermal drug delivery of chlorpheniramine maleate (CPM) was developed based on Span 40 and extensively characterized in vitro. The system was evaluated for the effect of composition of formulation, type of surfactants and alcohols on the
Acta poloniae pharmaceutica, 46(1), 70-73 (1989-01-01)
Influence of non-ionic tensides on liberation of chlorotetracycline hydrochloride from ointment bases was investigated. Non-ionic tensides were found to enhance liberation of chlorotetracycline hydrochloride from lipophilic ointment bases, while liberation of this antibiotic from hydrophilic ointment bases proved to be
Drug development and industrial pharmacy, 43(9), 1450-1459 (2017-04-20)
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential formation of niosomes from proniosome
Turkish journal of medical sciences, 45(6), 1403-1412 (2016-01-19)
The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats. Paclitaxel-loaded Span 40 niosomes were prepared using
Materials science & engineering. C, Materials for biological applications, 113, 110975-110975 (2020-06-04)
Hydrophobin-1 (HFB-1) found on the surface of fungal spores, plays a role in the lack of antigen recognition by the host immune system. The present study aimed to evaluate the potential application of HFB-1 for the delivery of doxorubicin (Dox)
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 27(1), 329-339 (2019-05-28)
The use of phytochemicals to prevent or suppress tumours is known as chemoprevention. Numerous plant-derived agents have been reported to have anticancer potentials. As one such anticancer phytochemical, diosgenin has several applications which are nevertheless limited due to its low
Journal of liposome research, 27(2), 118-129 (2016-04-16)
The current investigation aims to develop and evaluate novel ocular proniosomal gels of lomefloxacin HCl (LXN); in order to improve its ocular bioavailability for the management of bacterial conjunctivitis. Proniosomes were prepared using different types of nonionic surfactants solely and
The Journal of pharmacy and pharmacology, 46(8), 631-635 (1994-08-01)
A range of surfactants with different hydrophile-lipophile balance (HLB) values was selected to investigate the influence of interfacial properties on the uptake of oil droplets into complex coacervate microcapsules. The well characterized gelatin/acacia complex coacervate system was used in this
Journal of liposome research, 27(4), 312-323 (2016-06-01)
The aim of this study is to develop and evaluate niosomal dispersions loaded with the hydrophilic drug; lomefloxacin Hcl (LXN) for the management of ocular bacterial conjunctivitis. LXN-loaded niosomes were prepared by the thin film hydration method following a full
Journal of microencapsulation, 34(3), 250-261 (2017-05-31)
The aim of this study was to develop docetaxel-incorporated lipid nanoparticles (DTX-NPs) to improve the pharmacokinetic behaviour of docetaxel (DTX) after oral and parenteral administration via sustained release. DTX-NPs were prepared by nanotemplate engineering technique with palmityl alcohol as a
Luminescence : the journal of biological and chemical luminescence, 34(3), 360-367 (2019-03-01)
In this study, for the first time, calcium oxide (CaO)/polylactic acid nanoscaffolds were synthesized by co-precipitation assistant reverse micelles method. The physical and chemical (physicochemical) properties of the structures as dental resin composites were also studied. Nanocomposite materials as primary
International journal of pharmaceutics, 247(1-2), 103-114 (2002-11-14)
Creams from three components, surfactant, purified water and oil, were prepared. Comparable molar fractions of components were used in order to better understand the structural properties of the components used. The surfactants were sorbitan monoesters, sorbitan monolaurate, monopalmitate, monostearate and
Archives of pharmacal research, 38(4), 485-493 (2014-08-08)
The present study aimed to examine the chemical compositions of the essential oils of Beilschmiedia madang and their antioxidant, antibacterial, antifungal, anticholinesterase and anti-tyrosinase activities. The major constituents of the essential oils of leaf and bark of B. madang were
Pakistan journal of pharmaceutical sciences, 32(6(Supplementary)), 2879-2885 (2020-02-07)
In pharmaceuticals sciences, Fourier-transform infrared spectroscopy (FTIR) is a very useful technique to measure the compatibility and interaction between ingredients, therefore in the current study, compatibility of bergapten with different excipients was analyzed via FTIR. Nanostructured lipid carriers (NLCs) are
Avicenna journal of medical biotechnology, 7(2), 69-75 (2015-07-04)
Development of new drug carriers would be an interesting approach if it allowed increased efficacy of antibiotics and a reduction in doses, thus reducing the risk of developing resistance. As with most drug carriers, niosomes have been used to improve
Food & function, 11(10), 8878-8892 (2020-09-29)
Multiple O1/W/O2 nanoemulsions and O1/W nanoemulsions fortified with CLA or CoQ10 were produced using extra virgin olive or olive pomace oil and were also incorporated with polyphenols extracted from olive kernel to enhance their kinetic and chemical stability. They were
Food chemistry, 224, 139-143 (2017-02-06)
Aspergillus oryzae KB produces two β-fructofuranosidases (F1 and F2). F1 has high transferring activity and produces fructooligosaccharides from sucrose. Mycelial growth pellets were altered by the addition of Tween 20, 40 and 80 (HLB=16.7, 15.6 and 15.0, respectively) in liquid
Die Pharmazie, 66(8), 570-575 (2011-09-10)
Curcuminoids (curcumin, desmethoxycurcumin, and bisdesmethoxycurcumin) are major bioactive substances found in turmeric (Curcuma longa L.) extracts and possess antioxidant, anti-inflammatory, antimicrobial and anticancer properties. In this study, curcuminoid niosomes prepared with a series of Span non-ionic surfactants were developed to
Luminescence : the journal of biological and chemical luminescence, 36(3), 674-683 (2020-11-13)
A simple and sensitive flow injection-chemiluminescence (FI-CL) method was developed for determination of cetirizine dihydrochloride (CTZH) in pharmaceuticals. The method is primarily based on the enhancement effect of CTZH on the tris(2,2'-bipyridyl)ruthenium (II)-diperiodatoargentate (III) ([Ru(bpy)3 ]2+ -Ag(III) complex) CL system
AAPS PharmSciTech, 18(8), 3064-3075 (2017-05-19)
The objective of this study is to develop an oral formulation of famotidine niosomes coated with a mucoadhesive polymer, chitosan. Famotidine (FMT) has low oral bioavailability of 40-45% and short half-life between 2.5 to 4 h. Famotidine is classified as class
Drug design, development and therapy, 14, 3697-3721 (2020-09-29)
The current study aimed to discuss the potential of nanospanlastics as a surfactant-based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic acid (AKBA). AKBA is a potent anti-inflammatory drug, but it has poor oral bioavailability due to its poor
Materials science & engineering. C, Materials for biological applications, 76, 735-742 (2017-05-10)
A novel biopolymeric material in the form of nano/microspheres was developed which was capable of adsorbing coronaviruses. The biopolymer was obtained by crosslinking of chitosan (CHIT) with genipin, a nontoxic compound of plant origin, in inverted emulsion and reacting the
Pharmaceutical development and technology, 20(3), 330-336 (2013-12-18)
The aim of the present work was to extend our previous in-vitro drug release studies using semisolid dermatological bases with non-impregnated cellulose acetate membranes. A comparison of the performances of two apparatuses, the more commonly used Franz cell and the
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