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Showing 1-30 of 273 results for "398039" within Papers
Young Jin Jang et al.
Biochemical and biophysical research communications, 467(4), 941-947 (2015-10-17)
Shikonin is a naturally occurring naphthoquinone pigment and a major constituent present in Lithospermum erythrorhizon. Since microRNAs (miRNAs) are one of the key post-transcriptional regulators of adipogenesis, their manipulation represents a potential new strategy to inhibit adipogenesis. Our aim was
Tausif Zar et al.
Seminars in dialysis, 20(3), 217-219 (2007-06-09)
Propylene glycol is a commonly used solvent for oral, intravenous, and topical pharmaceutical preparations. Although it is considered safe, large intravenous doses given over a short period of time can be toxic. Underlying renal insufficiency and hepatic dysfunction raise risk
Julia S Rihm et al.
Neurobiology of learning and memory, 122, 142-151 (2015-05-03)
Emotional memories are reprocessed during sleep, and it is widely assumed that this reprocessing occurs mainly during rapid eye movement (REM) sleep. In support for this notion, vivid emotional dreams occur mainly during REM sleep, and several studies have reported
Monice M Fiume et al.
International journal of toxicology, 31(5 Suppl), 245S-260S (2012-10-25)
Propylene glycol is an aliphatic alcohol that functions as a skin conditioning agent, viscosity decreasing agent, solvent, and fragrance ingredient in cosmetics. Tripropylene glycol functions as a humectant, antioxidant, and emulsion stabilizer. Polypropylene glycols (PPGs), including PPG-3, PPG-7, PPG-9, PPG-12
Carla Caddeo et al.
International journal of pharmaceutics, 443(1-2), 128-136 (2013-01-10)
Diclofenac-loaded phospholipid vesicles, namely conventional liposomes, ethosomes and PEVs (penetration enhancer-containing vesicles) were developed and their efficacy in TPA (phorbol ester) induced skin inflammation was examined. Vesicles were made from a cheap and unpurified mixture of phospholipids and diclofenac sodium;
Y Yoshida
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 60(2), 183-194 (1985-03-01)
Methionine is a sulfur-containing essential amino acid and there are optic isomers of L- and D-type. It has been known that there are two metabolic pathways in methionine metabolism-the transsulfuration and the transamination. The purposes of the present investigation are
Hemant K Mishra et al.
Journal of leukocyte biology, 97(3), 447-454 (2014-11-22)
The chemokine receptor CXCR2 is expressed at high levels on circulating neutrophils and is critical for directing their migration to sites of inflammation. CXCR2 surface levels are rapidly modulated by 2 mechanisms-cell internalization and recycling upon ligand binding-and by a
Mutlaq M Al-Subaie et al.
International journal of nanomedicine, 10, 3973-3985 (2015-06-26)
This study aimed to formulate an optimized acyclovir (ACV) nanoemulsion hydrogel in order to provide a solution for the slow, variable, and incomplete oral drug absorption in patient suffering from herpes simplex viral infection. Solubility of ACV in different oils
Tomoka Takatani-Nakase et al.
PloS one, 7(10), e47980-e47980 (2012-10-31)
Transcutaneous immunization (TCI) is a novel vaccination strategy, which is expected to have therapeutic applications. However, to develop effective TCI systems, a simple, non-invasive and safe transdermal formulation is required. This study developed a novel TCI system utilizing the co-administration
A A Melo et al.
The Journal of laryngology and otology, 127(4), 359-363 (2013-02-15)
To determine whether the administration of mitomycin C prevents propylene glycol exposure from inducing middle-ear cholesteatoma and otitis media, in a rat model. Twenty-four Wistar rats underwent intratympanic injections on days 1, 8 and 15, via the tympanic membrane pars
One-pot tandem processing of glycerol stream to 1, 2-propanediol with methanol reforming as hydrogen donor reaction.
Vasiliadou ES, et al.
Applied Catalysis. B, Environmental, 163, 258-266 (2015)
Quiz page October 2013: When things are not as they seem: a woman with anion gap metabolic acidosis after ingesting antifreeze.
Aswani Alavala et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 62(4), A25-A28 (2013-09-24)
H Fromme et al.
Chemosphere, 90(11), 2714-2721 (2013-01-08)
Glycol ethers are a class of semi-volatile substances used as solvents in a variety of consumer products like cleaning agents, paints, cosmetics as well as chemical intermediates. We determined 11 metabolites of ethylene and propylene glycol ethers in 44 urine
Sabine Hauptstein et al.
International journal of pharmaceutics, 487(1-2), 25-31 (2015-04-04)
It was the aim of this study to investigate a novel strategy for oral gene delivery utilizing a self-nanoemulsifying drug delivery system (SNEDDS). After hydrophobic ion pairing a plasmid was incorporated into SNEDDS. The mean droplet size of resulting nanoemulsions
Adriana Machado-Lima et al.
Journal of cellular physiology, 230(6), 1250-1257 (2014-11-22)
Advanced glycation end products (AGE) are elevated in diabetes mellitus (DM) and predict the development of atherosclerosis. AGE-albumin induces oxidative stress, which is linked to a reduction in ABCA-1 and cholesterol efflux. We characterized the glycation level of human serum
Simultaneous determination of plasma phenethylamine, phenylethanolamine, tyramine and octopamine by high-performance liquid chromatography using derivatization with fluorescamine.
T Yonekura et al.
Journal of chromatography, 427(2), 320-325 (1988-06-03)
D Spadaro et al.
Journal of applied microbiology, 119(2), 510-520 (2015-05-16)
To identify cultivable filamentous fungi before ensiling, after silage conservation, in farm-silos covered with two different plastic films (polyethylene (PE) vs biodegradable (MB)), as well as after aerobic exposure of whole-crop corn silage. Molecular techniques coupled with traditional microbial counting
Lynda Uphouse
Behavioural brain research, 282, 95-102 (2015-01-17)
Regularly cycling Fischer female rats were treated with either a low (5mg/kg) or high (5mg/RAT; approximately 30mg/kg) dose of the antiprogestin, RU486, before the morning of proestrus or on the morning of proestrus. The emergence of sexual behavior after treatment
Raquel S Teixeira et al.
International journal of pharmaceutics, 474(1-2), 212-222 (2014-08-12)
The aim of this study is to investigate the efficacy of new, biocompatible, lysine-based surfactants as chemical permeation enhancers for two different local anesthetics, tetracaine and ropivacaine hydrochloride, topically administered. Results show that this class of surfactants strongly influences permeation
Catalytic Dehydration of 1,2-Propanediol into Propanal over Ag-Modified Silica-Alumina.
Sun D, et al.
Chemistry Letters (Jpn), 43(4), 450-452 (2014)
David J Kemble et al.
The journal of applied laboratory medicine, 5(2), 300-310 (2020-05-24)
Rapid identification and quantification of toxic alcohols and ethylene glycol is imperative for appropriate treatment. Clinical laboratories frequently rely on direct injection gas chromatography (GC) methods, but these methods require inlet maintenance and multiple GC systems. To overcome these challenges
Gai Ling Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 84(1-2), 49-57 (2002-10-26)
To achieve a therapeutical effect of the anti-Parkinson's drug R-apomorphine via iontophoresis delivery, enhancement strategies in vitro were explored using three structurally related enhancers, lauric acid (LA), dodecyltrimethylammonium bromide (DTAB) and Laureth-3 oxyethylene ether (C(12)EO(3)). Human stratum corneum and shed
Jayamanti Pandit et al.
Journal of liposome research, 24(2), 163-169 (2014-02-01)
Miconazole nitrate is a widely used antifungal agent, but its use in topical formulations is not efficacious because deep seated fungal infections are difficult to treat with conventional topical formulation. Miconazole nitrate loaded ultraflexible liposomes have been prepared and their
Yasaman Damestani et al.
Lasers in surgery and medicine, 46(6), 488-498 (2014-05-28)
Optical clearing agents (OCAs) have shown promise for increasing the penetration depth of biomedical lasers by temporarily decreasing optical scattering within the skin. However, their translation to the clinic has been constrained by lack of practical means for effectively perfusing
P D Yorgin et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 30(1), 134-139 (1997-07-01)
Propylene glycol is a solvent that is used in many oral, injectable, and topical medications. Although uncommon, acute renal failure has been attributed to propylene glycol. The mechanism of propylene glycol-mediated renal injury is unknown. We report a case of
Dehua Liao et al.
Drug delivery, 22(4), 516-521 (2014-01-29)
The aim of this research was to increase the oral bioavailability of puerarin by N-trimethyl chitosan-modified microemulsions (TMC-MEs) loaded with puerarin. Different concentrations of TMC-modified microemulsions were prepared in our study, and then evaluated for particle size, zeta potential, morphological
Erin K Zinkhan et al.
Pediatric research, 76(5), 432-440 (2014-08-15)
Intrauterine growth restriction (IUGR) increases the risk of adult-onset hypercholesterolemia. High-fat diet (HFD) consumption potentiates IUGR-induced increased cholesterol. Cholesterol is converted to bile acids by Cyp7a1 in preparation for excretion. We hypothesized that IUGR rats fed a HFD will have
Luc A Cynober
Nutrition (Burbank, Los Angeles County, Calif.), 18(9), 761-766 (2002-09-26)
The plasma concentration of an amino acid (AA) is the result of its rates of appearance (Ra) in and disappearance (Rd) from plasma. As for most nutrients, AA Ra and Rd are tightly regulated and at the postabsorptive state Ra
Jennifer D Larson et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(18), E1092-E1100 (2012-04-05)
Gammaherpesvirus infections, such as those caused by EBV, have been suggested to promote the development of autoimmunity. To test this idea, we infected healthy WT and lupus-prone B6.Sle123 mice with an EBV-related and rodent-specific gammaherpesvirus, γHV68. Although acute γHV68 infection
Shiow-Fern Ng et al.
Drug development and industrial pharmacy, 40(11), 1538-1546 (2013-09-13)
Topical emollients are known to provide symptomatic relief for atopic dermatitis. In hospitals, wet-wrap therapy has been shown to benefit children with moderate-to-severe atopic dermatitis (AD), but the application of wet-wraps is tedious and time-consuming. Topical emollients have low residence
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