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Showing 1-30 of 43 results for "41525" within Papers
E K Krasnowska et al.
Biophysical journal, 74(4), 1984-1993 (1998-04-17)
Fluorescence spectral features of 6-propionyl-2-dimethylaminonaphthalene (Prodan) in phospholipid vesicles of different phase states are investigated. Like the spectra of 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), the steady-state excitation and emission spectra of Prodan are sensitive to the polarity of the environment, showing a relevant
Masaki Goto et al.
Langmuir : the ACS journal of surfaces and colloids, 28(33), 12191-12198 (2012-07-25)
The myristoylpalmitoylphosphatidylcholine (MPPC) bilayer membrane shows a complicated temperature-pressure phase diagram. The large portion of the lamellar gel (L(β)'), ripple gel (P(β)'), and pressure-induced gel (L(β)I) phases exist as metastable phases due to the extremely stable subgel (L(c)) phase. The
Renata K Everett et al.
The journal of physical chemistry. A, 114(14), 4946-4950 (2010-03-25)
The synthesis and photophysical properties of 7-(dimethylamino)-3,4-dihydrophenanthren-1(2H)-one (7) and 3-(dimethylamino)-8,9,10,11-tetrahydro-7H-cyclohepta[a]naphthalen-7-one (8) are reported. These compounds possess a cycloalkanone substructure that controls the extent of twisting of the carbonyl group. The six-membered ring in 7 forces the carbonyl group to be
Masaki Goto et al.
Colloids and surfaces. B, Biointerfaces, 84(1), 55-62 (2011-01-15)
The bilayer phase behavior of asymmetric phospholipids, palmitoylstearoylphosphatidylcholine (PSPC) and stearoylpalmitoylphosphatidylcholine (SPPC), with different vesicle sizes (large multilamellar vesicle (LMV) and giant multilamellar vesicle (GMV)) was investigated by fluorescence spectroscopy using a polarity-sensitive fluorescent probe Prodan under high pressure. The
Snezhana M Bakalova et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(1), 36-40 (2008-11-18)
Vertical S(1)-S(0) electronic transitions of the highly solvent-sensitive fluorescence label 2-propionyl-6-dimethylamino naphthalene (PRODAN) are modeled by semiempirical CISD AM1 and TD DFT calculations in a large number of solvents of different polarity and hydrogen donating ability. Calculations correctly reproduce the
D Krilov et al.
European biophysics journal : EBJ, 37(7), 1105-1110 (2008-02-08)
FT Raman spectroscopy has been applied to determine the location of PRODAN within HDL and to investigate its influence on the structure of the particle. The complex spectra of HDL and HDL labeled with PRODAN were divided into three regions
E K Krasnowska et al.
Biochimica et biophysica acta, 1511(2), 330-340 (2001-04-05)
The fluorescent membrane probe 6-propionyl-2-dimethylaminonaphthalene (Prodan) displays a high sensitivity to the polarity and packing properties of lipid membrane. Contrary to 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), Prodan can also monitor the properties of the membrane surface, i.e., the polar-head pretransition. In bilayers composed
Hitoshi Matsuki et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183197-183197 (2020-01-21)
The bilayer phase transitions of medium-chain phosphatidylcholines with linear saturated acyl chains (Cn = 12, 13 and 14) were measured by high-pressure light-transmittance measurements and differential scanning calorimetry to investigate the formation of intermediate gel-liquid crystalline phase called Lx phase. The constructed
Larissa Socrier et al.
Biochimica et biophysica acta, 1859(12), 2495-2504 (2017-10-07)
Free radical scavengers such as α-phenyl-N-tert-butylnitrone (PBN) have been widely used as protective agents in several biological models. We recently designed two PBN derivatives by adding a cholesterol moiety to the parent nitrone to increase its lipophilicity. In addition to
Ramkrishna Adhikary et al.
The journal of physical chemistry. B, 113(35), 11999-12004 (2009-08-28)
The coexistence of different excited states with different properties of the same chromophores could have significant consequences for the accurate characterization of solvation dynamics in a heterogeneous environment, such as a protein. The purpose of this work is to study
Hitesh S Purohit et al.
Molecular pharmaceutics, 12(5), 1623-1635 (2015-04-09)
The purpose of this study was to develop a novel fluorescence technique employing environment-sensitive fluorescent probes to study phase separation kinetics in hydrated matrices of amorphous solid dispersions (ASDs) following storage at high humidity and during dissolution. The initial miscibility
Lukasz Cwiklik et al.
The journal of physical chemistry. A, 115(41), 11428-11437 (2011-09-14)
Absorption and fluorescence spectra of PRODAN (6-propionyl-2-dimethylaminonaphthalene) were studied by means of the time-dependent density functional theory and the algebraic diagrammatic construction method. The influence of environment, a phosphatidylcholine lipid bilayer and water, was taken into account employing a combination
K Rieber et al.
Biochimica et biophysica acta, 1768(5), 1050-1058 (2007-02-16)
The subject of this report was to investigate headgroup hydration and mobility of two types of mixed lipid vesicles, containing nonionic surfactants; straight chain Brij 98, and polysorbat Tween 80, with the same number of oxyethylene units as Brij, but
Masaki Goto et al.
Langmuir : the ACS journal of surfaces and colloids, 26(16), 13377-13384 (2010-08-11)
The bilayer phase behavior of diheptadecanoylphosphatidylcholine (C17PC) with different vesicle sizes (large multilamellar vesicle (LMV) and giant multilamellar vesicle (GMV)) was investigated by fluorescence spectroscopy using a polarity-sensitive fluorescent probe Prodan under atmospheric and high pressures. The difference in phase
Corina L Reichert et al.
Journal of food science, 80(11), E2495-E2503 (2015-10-13)
The miscibility behavior of mixed surfactant systems and the influence of extrinsic parameters are crucial for their application as emulsifiers. Therefore, the objective of this study was to evaluate the miscibility behavior of mixed systems composed of commercial Quillaja saponin
Jadwiga Maniewska et al.
Acta biochimica Polonica, 65(2), 185-191 (2018-05-26)
The purpose of the present work was to assess the ability of five new oxicam analogues to interact with the lipid bilayers. To characterize the interaction of newly synthesized NSAIDs (non-steroidal anti-inflammatory drugs) analogues with DPPC lipid bilayers the two
Masaki Goto et al.
Biochimica et biophysica acta, 1778(4), 1067-1078 (2008-01-15)
The bilayer phase transitions of palmitoylstearoyl-phosphatidylcholine (PSPC), diheptadecanoyl-PC (C17PC) and stearoylpalmitoyl-PC (SPPC) which have the same total carbon numbers in the two acyl chains were observed by differential scanning calorimetry and high-pressure optical method. As the temperature increased, these bilayers
Francesco Tres et al.
International journal of pharmaceutics, 543(1-2), 29-37 (2018-03-25)
Amorphous solid dispersions (ASDs) are a promising formulation strategy to increase both the apparent aqueous solubility and bioavailability of poorly water-soluble drugs. Upon dissolution under nonsink conditions, ASDs can generate highly supersaturated drug solutions which can undergo liquid-liquid phase separation
Giulia Parisio et al.
The journal of physical chemistry. B, 115(33), 9980-9989 (2011-07-21)
We have studied the emission features of the fluorescent polarity-sensitive probes known as Prodan and Laurdan in a liquid-crystalline DPPC bilayer. To this purpose, we have combined high-level quantum mechanical electronic structure calculations with a molecular field theory for the
Justyna Barucha-Kraszewska et al.
Biochimica et biophysica acta, 1798(9), 1724-1734 (2010-06-01)
Fluorescence methods are widely used in studies of biological and model membranes. The dynamics of membrane fluorescent markers in their ground and excited electronic states and correlations with their molecular surrounding within the fully hydrated phospholipid bilayer are still not
Jan Karolin et al.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2009, 4154-4157 (2009-12-08)
Hydrated nanopores offer a unique environment for studying biological molecules under controlled conditions and fabricating sensors using fluorescence. Silica nanopores for example are non-toxic, biologically and optically compatible with protein, and can be easily synthesized to entrap protein and exclude
Masaki Goto et al.
Annals of the New York Academy of Sciences, 1189, 68-76 (2010-03-18)
The bilayer phase behavior of symmetric and asymmetric phosphatidylcholines (PCs), 1,2-diheptadecanoyl-PC (C17PC), 1-palmitoyl-2-stearoyl-PC (PSPC), and 1-stearoyl-2-palmitoyl-PC (SPPC), with different vesicle sizes were investigated by a high-pressure fluorescence method using the polarity-sensitive fluorescent probe Prodan. The second derivative of fluorescence spectra
Yu Winston Wang et al.
Journal of biomedical optics, 23(4), 1-8 (2018-04-17)
Surface-enhanced Raman scattering (SERS) nanoparticles (NPs) are increasingly being engineered for a variety of disease-detection and treatment applications. For example, we have previously developed a fiber-optic Raman-encoded molecular imaging (REMI) system for spectral imaging of biomarker-targeted SERS NPs topically applied
Praveen Gadad et al.
Water research, 41(19), 4488-4496 (2007-07-17)
Noncovalent interactions between the fluorescent probe 6-propionyl-2-dimethylaminonaphthalene (PRODAN) and dissolved Norman Landfill leachate fulvic acid, Suwannee River fulvic acid, Suwannee River humic acid, and Leonardite humic acid were examined as a function of pH, fulvic and humic acid (FA and
Kazuki Tainaka et al.
Journal of the American Chemical Society, 129(15), 4776-4784 (2007-03-24)
A solvatochromic fluorophore, PRODAN, has been used as a microenvironment-sensitive reporter. Based on the chemistry of PRODAN, we designed and synthesized four novel fluorescent nucleosides, PDNX (X = U, C, A, and G), to which a PRODAN fluorophore was attached
Gesche Först et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 87(3), 559-569 (2014-04-01)
Since pharmacokinetic and pharmacodynamic activities of drugs are often related to their interactions with biomembranes, it is of high interest to establish an approach for the characterization of these interactions at the molecular level. For the present study, beta-blockers (oxprenolol
Ramachandram Badugu et al.
Journal of biomedical optics, 23(5), 1-9 (2018-05-19)
Accurate and reliable monitoring of blood glucose is needed for the treatment of diabetes, which has many challenges, including lack of patient compliance. Measuring tear glucose is an alternative to traditional finger-stick tests used to track blood sugar levels, but
János Erostyák et al.
Annals of the New York Academy of Sciences, 1130, 52-55 (2008-07-04)
We report a pump-probe experiment revealing the temporal evolution of subpicosecond evolution of Prodan's excited-state absorption in dimethylformamide. Also, we present calculation of the first spectral moment of this spectral band and estimation of different relaxation components on the subpicosecond
Dipayan Bose et al.
Cytoskeleton (Hoboken, N.J.), 76(6), 383-397 (2019-08-10)
Spectrin, the major protein of the erythrocyte membrane skeleton has canonically been thought to only serve a structural function. We have previously described a novel chaperone-like property of spectrin and also hypothesized that the chaperone activity and binding of a
Silvina S Quintana et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 13(1), 115-123 (2011-12-03)
The water/sodium bis(2-ethylhexyl) phosphate (NaDEHP) reverse micelle (RM) system is revisited by using, for the first time, molecular probes to investigate interface properties. The solvatochromic behavior of 1-methyl-8-oxyquinolinium betaine (QB) and 6-propionyl-2-(N,N-dimethyl)aminonaphthalene (PRODAN) in the water/NaDEHP/toluene system is studied, and
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