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Showing 1-30 of 2007 results for "439126" within Papers
Oluwatomide Adeoye et al.
Acta poloniae pharmaceutica, 71(5), 803-811 (2014-11-05)
The study evaluated two novel coprocessed excipients (with two methods) as disintegrants in an orally disintegrating paracetamol tablet formulation. The tablets produced were assessed for mechanical properties with the use of friability and tensile strength while the release properties were
Ali Es-Haghi et al.
Talanta, 128, 231-236 (2014-07-26)
Sol-gel based solid-phase microextraction fibers supported by a stainless steel wire were fabricated and employed for GC-MS determination of oxadiargyl in real samples. The fibers were based on four compounds with different polarity: polar and non-polar (end-capped) poly(dimethylsiloxane) (PDMS), polyethylene
C T Nielsen et al.
Lupus, 24(11), 1150-1160 (2015-04-04)
A high level of galectin-3-binding protein (G3BP) appears to distinguish circulating cell-derived microparticles in systemic lupus erythematosus (SLE). The aim of this study is to characterize the population of G3BP-positive microparticles from SLE patients compared to healthy controls, explore putative
Ester Boix-Garriga et al.
Nanotechnology, 26(36), 365104-365104 (2015-08-22)
Poly(D, L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) are being considered as nanodelivery systems for photodynamic therapy. The physico-chemical and biological aspects of their use remain largely unknown. Herein we report the results of a study of PLGA NPs for the delivery of
Sampa Maiti et al.
Talanta, 141, 116-121 (2015-05-13)
A new, simple, rapid and selective spectrophotometric method has been developed for detection and estimation of butanol in fermentation broth. The red colored compound, produced during reduction of diquat-dibromide-monohydrate with 2-mercaptoethanol in aqueous solution at high pH (>13), becomes purple
Lintao Zhao et al.
Cellular immunology, 293(2), 130-136 (2015-01-27)
TNF-alpha plays an important role in the development of secondary lymphoid tissues. Earlier studies showed that fibroblastic reticular cells express TNF-alpha receptor, suggesting that TNF-alpha may affect the development of FRCs. To test this, we analyzed the development and function
Prakash M Gopalakrishnan Nair et al.
Ecotoxicology and environmental safety, 113, 302-313 (2014-12-22)
In this study, the morphological, physiological and molecular level effects of copper oxide nanoparticles (CuONPs) were studied in an economically important oil seed crop Brassica juncea L. The possible involvement of lignification on shoot-root growth retardation was also studied. The
Catarina Oliveira Silva et al.
International journal of pharmaceutics, 493(1-2), 271-284 (2015-07-30)
Topical glucocorticosteroids were incorporated into nanocarrier-based formulations, to overcome side effects of conventional formulations and to achieve maximum skin deposition. Nanoparticulate carriers have the potential to prolong the anti-inflammatory effect and provide higher local concentration of drugs, offering a better
Sung Hoon Kim et al.
Journal of the American Chemical Society, 137(32), 10326-10335 (2015-07-18)
Estrogen conjugates with a polyamidoamine (PAMAM) dendrimer have shown remarkably selective regulation of the nongenomic actions of estrogens in target cells. In response to pH changes, however, these estrogen-dendrimer conjugates (EDCs) display a major morphological transition that alters the accessibility
Li Wang et al.
The Journal of biological chemistry, 289(52), 35731-35742 (2014-11-08)
Our previous study demonstrated that the NGX6b gene acts as a suppressor in the invasion and migration of nasopharyngeal carcinoma (NPC). Recently, we identified the novel isoform NGX6a, which is longer than NGX6b. In this study, we first found that
Asuka Yuda et al.
Journal of cellular physiology, 230(1), 150-159 (2014-06-07)
Appropriate mechanical loading during occlusion and mastication play an important role in maintaining the homeostasis of periodontal ligament (PDL) tissue. Connective tissue growth factor (CTGF/CCN2), a matricellular protein, is known to upregulate extracellular matrix production, including collagen in PDL tissue.
Heba A Hazzah et al.
International journal of pharmaceutics, 492(1-2), 248-257 (2015-07-21)
This study aimed to prepare and evaluate mucoadhesive sponges as dosage forms for delivering solid lipid nanoparticles. For this purpose curcumin (Cur) was formulated as solid nanoparticles (SLN) using Gelucire 50/13, and polaxomer 407. The prepared CurSLN dispersion was thickened
Nina Burger et al.
Nanomedicine : nanotechnology, biology, and medicine, 10(6), 1365-1373 (2014-03-29)
Gold nanoparticles (GNP) enhance the absorbance of photons thereby increasing emission of Auger-/photoelectrons in the nm-μm range. Yet, a major disadvantage is their diameter-dependent cellular uptake with an optimum of ~50 nm which may not offer optimal radiosensitization. A method
Kim A Lindblade et al.
Malaria journal, 14, 31-31 (2015-01-30)
Insecticide-treated bed nets (ITNs) are the cornerstone of malaria control in sub-Saharan Africa but their effectiveness may be compromised by the spread of pyrethroid resistance among malaria vectors. The objective of this investigation was to assess the effectiveness of ITNs
Xin-Zhang Cai et al.
Journal of cellular biochemistry, 116(7), 1431-1441 (2015-02-05)
Nasopharyngeal carcinoma (NPC) is a common disease in the southern provinces of China with a poor prognosis. To better understand the pathogenesis of NPC and identify proteins involved in NPC carcinogenesis, we applied iTRAQ coupled with two-dimensional LC-MS/MS to compare
Suguru Yamamoto et al.
Atherosclerosis, 242(1), 56-64 (2015-07-18)
Chronic kidney disease (CKD) amplifies atherosclerosis, which involves renin-angiotensin system (RAS) regulation of macrophages. RAS influences peroxisome proliferator-activated receptor-γ (PPARγ), a modulator of atherogenic functions of macrophages, however, little is known about its effects in CKD. We examined the impact
M Plaza-Oliver et al.
International journal of pharmaceutics, 490(1-2), 209-218 (2015-05-23)
Most frequently the use of bioactive molecules for the supplementation of food and beverages is hampered by stability limitations or inadequate intestinal absorption. This work evaluates in vitro the role that the interface of the nanoemulsion has on the physicochemical
Nazli Boke Sarikahya et al.
Natural product communications, 10(7), 1195-1198 (2015-09-29)
Crude acetone and ethanol extracts of the aerial parts of 21 Cephalaria species collected from Turkey were investigated for larvicidal and adult topical activity against Aedes aegypti. The ethanol extracts from C. elazigensis var. purpurea, C. anatolica, and C. elmaliensis
Lijuan Luo et al.
Scientific reports, 5, 12776-12776 (2015-08-05)
Algal blooms cause great damage to water quality and aquaculture. However, this study showed that dead algal cells and chlorophyll could accelerate the photo-transformation of benzo[a]pyrene (BaP), a ubiquitous and persistent pollutant with potently mutagenic and carcinogenic toxicities, under visible
Edward Bormashenko et al.
The European physical journal. E, Soft matter, 38(1), 2-2 (2015-01-27)
The fine structure of the three-phase (triple) line was studied for different liquids, various topographies of micro-rough substrates and various wetting regimes. Wetting of porous and pillar-based micro-scaled polymer surfaces was investigated. The triple line was visualized with the environmental
Samantha K Schmitt et al.
Advanced healthcare materials, 4(10), 1555-1564 (2015-05-23)
Human mesenchymal stem cells (hMSCs) are a widely available and clinically relevant cell type with a host of applications in regenerative medicine. Current clinical expansion methods can lead to selective changes in hMSC phenotype potentially resulting from relatively undefined cell
J R Gapes
Journal of molecular microbiology and biotechnology, 2(1), 27-32 (2000-08-11)
Acetone-butanol (AB) fermentation was once run commercially in many countries until these chemicals could be made more cheaply from fossil oil sources. Research into the revitalisation of the process has shown that the process could once again be run economically
Yared Merdassa et al.
Journal of AOAC International, 98(1), 192-200 (2015-04-11)
A rapid, efficient, and simple one-step ultrasound-assisted extraction (UAE) method was developed for the analysis of seven fungicides (cymoxanil, metalaxyl, mandipropamid, folpet, chlorothalonil, kresoxim-methyl, and famoxadone) in horticultural soils. Analytes in the samples were determined by HPLC with variable wavelength
Hangeun Kim et al.
Journal of microbiology (Seoul, Korea), 53(1), 47-52 (2014-12-05)
Lactobacillus plantarum is a well-documented probiotic that has been used in clinical trials for the regulation of the immune system and treatment of gastrointestinal diseases. In this study, we evaluated the effects of L. plantarum cell lysates on the immune
Fotini A Trikka et al.
BMC genomics, 16, 935-935 (2015-11-18)
Salvia diterpenes have been found to have health promoting properties. Among them, carnosic acid and carnosol, tanshinones and sclareol are well known for their cardiovascular, antitumor, antiinflammatory and antioxidant activities. However, many of these compounds are not available at a
Yujie Wen et al.
Stem cells (Dayton, Ohio), 32(10), 2732-2743 (2014-07-22)
CD8(+) TCR(-) graft facilitating cells (FCs) enhance engraftment of hematopoietic stem cells (HSCs) in allogeneic and syngeneic recipients. The mechanisms by which FCs promote HSC engraftment and tolerance induction have not been fully elucidated. Here, we provide data to support
Niek G J Leus et al.
International journal of pharmaceutics, 469(1), 121-131 (2014-04-22)
In recent years much research in RNA nanotechnology has been directed to develop an efficient and clinically suitable delivery system for short interfering RNA (siRNA). The current study describes the in vivo siRNA delivery using PEGylated antibody-targeted SAINT-based-lipoplexes (referred to
Malgorzata Kotula-Balak et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(3), 529-537 (2015-01-03)
Our previous studies revealed that in bank vole testicular cells octylphenol (OP) action is related either to its binding to estrogen receptors or increasing cAMP level that modulates spermatozoa motility and acrosome reaction (AR), (Kotula-Balak et al., 2011, 2014). To
Zachary Yu-Ching Lin et al.
Developmental biology, 400(1), 43-58 (2015-01-28)
Mammalian spermatogenesis has been investigated extensively in rodents and a strictly controlled developmental process has been defined at cellular and molecular levels. In comparison, primate spermatogenesis has been far less well characterized. However, important differences between primate and rodent spermatogenesis
Francesca Cargnin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(50), 16650-16661 (2014-12-17)
The RE1 Silencing Transcription Factor (REST) acts as a governor of the mature neuronal phenotype by repressing a large consortium of neuronal genes in non-neuronal cells. In the developing nervous system, REST is present in progenitors and downregulated at terminal
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