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Showing 1-30 of 492 results for "494488" within Papers
Byoung Chan Kim et al.
Proteomics, 9(7), 1893-1900 (2009-03-17)
A stable and robust trypsin-based biocatalytic system was developed and demonstrated for proteomic applications. The system utilizes polymer nanofibers coated with trypsin aggregates for immobilized protease digestions. After covalently attaching an initial layer of trypsin to the polymer nanofibers, highly
Matthew D Overturf et al.
Aquatic toxicology (Amsterdam, Netherlands), 161, 33-40 (2015-02-11)
Pharmaceuticals are routinely detected in the environment; and several of these compounds have been extensively researched due to their potential impacts to the endocrine system of aquatic organisms. The negative reproductive consequences of synthetic progestins in teleost species have only
P Zuccaro et al.
Journal of chromatography, 621(2), 257-261 (1993-11-24)
A simple and reliable reversed-phase high-performance liquid chromatographic method with ultraviolet detection is described for the quantitation of nicotine and its metabolites cotinine, trans-3'-hydroxycotinine, norcotinine and cotinine N-oxide in human serum. The analytes and the internal standard, N-ethylnorcotinine, were extracted
Elisa Dassie et al.
International journal of nanomedicine, 10, 6811-6823 (2015-11-21)
For many years, novel strategies for cancer detection and treatment using nanoparticles (NPs) have been developed. Esophageal adenocarcinoma is the sixth leading cause of cancer-related deaths in Western countries, and despite recent advances in early detection and treatment, its prognosis
Gerald L Kennedy
Critical reviews in toxicology, 42(10), 793-826 (2012-09-28)
Dimethylacetamide (DMAC) and dimethylformamide (DMF) continue to be important, widely used solvents involved in a wide variety of industrial applications. As liquids with relatively low vapor pressures, contact with both the integumentary and respiratory systems is the main source of
F Ibrahim et al.
Luminescence : the journal of biological and chemical luminescence, 30(7), 1011-1019 (2015-03-03)
A rapid, simple, accurate and highly sensitive spectrofluorimetric method was developed for the simultaneous analysis of nebivolol hydrochloride (NEB) and amlodipine besylate (AML). The method was based on measuring the synchronous fluorescence intensity of the drugs at ĪĪ» = 40
Fuyou Du et al.
Analytica chimica acta, 845, 45-52 (2014-09-10)
In this publication, a novel solid phase microextraction (SPME) coating functionalized with a DNA aptamer for selective enrichment of a low abundance protein from diluted human plasma is described. This approach is based on the covalent immobilization of an aptamer
Enaam Jamal Al Dine et al.
Environmental science and pollution research international, 22(22), 17850-17859 (2015-07-15)
In this study, pine needles were used as cost-effective and reliable passive bio-monitors to concomitantly evaluate atmospheric concentrations of three classes of persistent organic pollutants, polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), and polycyclic aromatic hydrocarbons (PAHs). The extraction of persistent
Nardine S Abadeer et al.
ACS nano, 8(8), 8392-8406 (2014-07-26)
Plasmonic nanoparticles can strongly interact with adjacent fluorophores, resulting in plasmon-enhanced fluorescence or fluorescence quenching. This dipolar coupling is dependent upon nanoparticle composition, distance between the fluorophore and the plasmonic surface, the transition dipole orientation, and the degree of spectral
Attractors in Sequence Space: Peptide Morphing by Directed Simulated Evolution.
Jan A Hiss et al.
Molecular informatics, 34(11-12), 709-714 (2016-01-19)
Claudia Orelio et al.
Haematologica, 94(3), 409-413 (2009-02-13)
Shwachman-Diamond syndrome is a hereditary disorder characterized by pancreatic insufficiency and bone marrow failure. Most Shwachman-Diamond syndrome patients have mutations in the SBDS gene located at chromosome 7 and suffer from recurrent infections, due to neutropenia in combination with impaired
Jeffrey R Alston et al.
Physical chemistry chemical physics : PCCP, 17(44), 29566-29573 (2015-10-13)
In order to enhance the electrical energy storage capabilities of nanostructured carbon materials, inter-particle spacer strategies are needed to maintain ion-accessible surface area between the nanoparticles. This paper presents a comparison between different classes of divalent, dinuclear coordination complexes which
Jae Kyoo Lee et al.
Quarterly reviews of biophysics, 48(4), 437-444 (2015-11-06)
Using high-resolution mass spectrometry, we have studied the synthesis of isoquinoline in a charged electrospray droplet and the complexation between cytochrome c and maltose in a fused droplet to investigate the feasibility of droplets to drive reactions (both covalent and
Vinitha Ganesan et al.
Biochimica et biophysica acta, 1854(6), 592-600 (2014-12-04)
Immunoprecipitation (IP) is a widely used technique for identifying the binding partners of the target proteins of specific antibodies. Putative binding targets and their partners are usually in much lower amounts than the antibodies used to capture these target proteins.
Thomas Schettgen et al.
Rapid communications in mass spectrometry : RCM, 22(17), 2629-2638 (2008-07-31)
Mercapturic acids are highly important and specific biomarkers of exposure to carcinogenic substances in occupational and environmental medicine. We have developed and validated a reliable, specific and very sensitive method for the simultaneous determination of five mercapturic acids derived from
S Rudnick-Glick et al.
Journal of nanobiotechnology, 13, 80-80 (2015-11-19)
Bisphosphonate (BP) compounds are widely used in the treatment of bone disorders. This group of drugs with a high affinity to Ca(+2) ions is rapidly attracted to bone mineral, especially in areas of high resorption. We have engineered unique biodegradable
Wen Shi et al.
Biomaterials, 35(22), 5760-5770 (2014-04-24)
N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, hinders the detection of resident or nearby metastatic lesions thereby decreasing diagnostic effectiveness. Our laboratory has
Daishun Ling et al.
ACS nano, 8(8), 8027-8039 (2014-08-06)
Hepatocellular carcinoma (HCC) has one of the worst prognoses for survival as it is poorly responsive to both conventional chemotherapy and mechanism-directed therapy. This results from a lack of therapeutic concentration in the tumor tissue coupled with the highly toxic
Akiyoshi Hirata et al.
Journal of the American Chemical Society, 136(32), 11546-11554 (2014-07-19)
A polyamide containing N-methylpyrrole (Py) and N-methylimidazole (Im), designated PIPA, binds with high affinity and specificity to specific nucleotide sequences in the minor groove of double-helical DNA. Based on a recent report of the synthesis of PIPA for telomere visualization
Seyedsina Moeinzadeh et al.
Tissue engineering. Part A, 21(1-2), 134-146 (2014-07-23)
An attractive approach to reduce the undesired side effects of bone morphogenetic proteins (BMPs) in regenerative medicine is to use osteoinductive peptide sequences derived from BMPs. Although the structure and function of BMPs have been studied extensively, there is limited
Ryan J Wade et al.
Nature communications, 6, 6639-6639 (2015-03-24)
Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases. Here we synthesize reactive
Haoyu Liu et al.
Carbohydrate polymers, 113, 480-489 (2014-09-27)
Polymer design and selection are crucial to the development of amorphous solid dispersions (ASD) for solubilization of otherwise poorly water-soluble drugs. The matrix polymer is required to interact strongly at the molecular level with the drug to prevent recrystallization, but
Fouzi Mouffouk et al.
International journal of nanomedicine, 10, 63-76 (2015-01-08)
Early cancer detection is a major factor in the reduction of mortality and cancer management cost. Here we developed a smart and targeted micelle-based contrast agent for magnetic resonance imaging (MRI), able to turn on its imaging capability in the
Margherita Di Pisa et al.
Journal of medicinal chemistry, 58(3), 1390-1399 (2015-01-15)
Celiac disease (CD) patients usually present high levels of circulating IgA antibodies directed to different antigens, in particular tissue transglutaminase (tTG), gliadin (Glia), and endomysium. A series of synthetic peptide constructs containing cross-linked tTG and Glia deamidated peptides have been
Michael Eck et al.
Physical chemistry chemical physics : PCCP, 16(24), 12251-12260 (2014-05-14)
We present a significant efficiency enhancement of hybrid bulk heterojunction solar cells by utilizing CdSe quantum dots attached to reduced graphene oxide (rGO) as the electron accepting phase, blended with the PCPDTBT polymer. The quantum dot attachment to rGO was
Hamed Daemi et al.
Carbohydrate polymers, 112, 638-647 (2014-08-19)
The novel soluble alginate-based polyurethanes in organic solvents were synthesized by the reaction of NCO-terminated prepolymers and tributylammonium alginate (TBA-Alg) for the first time. The chemical structures of synthesized polyurethanes were characterized using FTIR, (1)H NMR and TGA. The reaction
Mir Ali Farajzadeh et al.
Talanta, 146, 772-779 (2015-12-24)
In this paper, a new extraction method based on counter current salting-out homogenous liquid-liquid extraction (CCSHLLE) followed by dispersive liquid-liquid microextraction (DLLME) has been developed for the extraction and preconcentration of widely used pesticides in fruit juice samples prior to
Patrizia Marchetti et al.
Scientific reports, 5, 17353-17353 (2015-12-03)
Thin film composite membranes were prepared through a facile single-step wire-wound rod coating procedure in which internally crosslinked poly(styrene-co-butadiene) polymer nanoparticles self-assembled to form a thin film on a hydrophilic ultrafiltration support. This nanoparticle film provided a defect-free separation layer
Mauricio Mora-Pale et al.
Biotechnology and bioengineering, 112(12), 2417-2428 (2015-06-26)
Plant polyphenols are known to have varying antimicrobial potencies, including direct antibacterial activity, synergism with antibiotics and suppression of bacterial virulence. We performed the in vitro oligomerization of resveratrol catalyzed by soybean peroxidase, and the two isomers (resveratrol-trans-dihydrodimer and pallidol)
Andrea M Binnebose et al.
PLoS neglected tropical diseases, 9(10), e0004173-e0004173 (2015-10-27)
Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. Targeting
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