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Showing 1-30 of 173 results for "56-38-2" within Papers
Brandie Heald et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(10), 1336-1340 (2013-02-13)
In 2009, the Evaluation of Genomic Applications in Practice and Prevention recommended that all colorectal cancers (CRCs) be screened for Lynch syndrome (LS) through microsatellite instability (MSI) or immunohistochemistry (IHC). No studies report how this process is implemented on a
Gang Zheng et al.
Experimental and molecular pathology, 94(1), 29-32 (2012-06-19)
LMP2 is a subunit of the immunoproteasome that is overexpressed in oncocytic lesions of the thyroid gland. This study was designed to assess the expression profile and diagnostic utility of LMP2 in two renal oncocytic tumors that share similar morphologic
Yi-hui Ma et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 39(1), 5-9 (2010-04-15)
To investigate the expression of Twist, E-cadherin and N-cadherin in breast carcinoma tissue and to analyse their effects on the breast carcinoma differentiation, size, infiltration and metastasis of the breast carcinoma. The expression of Twist, E-cadherin and N-cadherin in 56
Xiangmin He et al.
Zhonghua yi xue za zhi, 82(10), 685-688 (2002-07-23)
To investigate the polymorphisms of interleukin-1B (IL-1B) promotor region 31 C/T and interleukin-1 receptor antagonist (IL-1RN) gene and the relationship between the genotype of IL-1 and IL-1RN and susceptibility to gastric cancer in Chinese population. Genomic DNA was extracted from
MaryAnn J Matney et al.
Journal of animal science, 99(10) (2021-09-14)
The objective of this study was to determine effects of extended aging and intramuscular location on Warner-Bratzler shear force (WBSF), muscle fiber cross-sectional area (CSA), and protein degradation of semitendinosus (ST) and longissimus lumborum (LL) steaks. Left ST and LL
Akitomo Yokokawa et al.
European journal of drug metabolism and pharmacokinetics, 46(2), 317-324 (2021-02-24)
Irinotecan (CPT-11) is metabolized to an active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) by carboxylesterase (CES). SN-38 is then converted to the inactive metabolite SN-38 glucuronide (SN-38G) by glucuronosyltransferase 1A1 (UGT1A1). Genetic polymorphisms in UGT1A1 have been associated with altered SN-38 pharmacokinetics, which
Bing Z Carter et al.
Apoptosis : an international journal on programmed cell death, 16(1), 67-74 (2010-10-13)
XIAP, a potent caspase inhibitor, is highly expressed in acute myeloid leukemia (AML) cells and contributes to chemoresistance. A multi-center phase 1/2 trial of XIAP antisense oligonucleotide AEG35156 in combination with idarubicin/cytarabine was conducted in 56 patients with relapsed/refractory AML.
H Nakauchi et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(15), 5126-5130 (1985-08-01)
The sequence of Lyt-2 cDNA shows that it is a new member of the immunoglobulin super gene family. Analysis of the predicted amino acid sequence indicates that the Lyt-2 polypeptide is synthesized with a 27-amino acid leader, and that the
Paloma Valenzuela et al.
Clinical and experimental medicine, 21(1), 149-159 (2020-10-14)
Metronomic chemotherapy has shown promising antitumor activity in a number of malignancies. We previously reported a phase II clinical trial of metronomic UFT (a 5-fluorouracil prodrug; 100 mg/twice per day p.o.) and cyclophosphamide (CTX; 500 mg/m2 i.v. bolus on day 1 and
Theresa Hahn et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 16(6), 801-808 (2010-01-16)
Toxicity after blood and marrow transplantation (BMT) has interindividual variability that may be explained by common genetic polymorphisms in critical pathways. The glutathione-S-transferase (GST) isoenzymes detoxify the reactive oxygen species generated by chemotherapy agents and radiation. We investigated whether deletion
Y Gao et al.
The Journal of biological chemistry, 276(50), 47530-47541 (2001-10-12)
Signaling specificity of Rho GTPase pathways is achieved in part by selective interaction between members of the Dbl family guanine nucleotide exchange factors (GEFs) and their Rho GTPase substrates. For example, Trio, GEF-H1, and Tiam1 are a subset of GEFs
Sokbom Kang et al.
Gynecologic oncology, 118(1), 58-63 (2010-04-28)
Using pharmacologic unmasking and genome-wide differential methylation analysis, we identified a novel methylated gene in ovarian cancers. Two ovarian cancer cells (OVCAR-3, ES-2) that showed synergistic growth inhibition by 5-aza-dC and cisplatin were selected. After treatment with 5-aza-dC, differential expression
Minglian Zhang et al.
Molecular genetics and metabolism, 101(2-3), 192-199 (2010-08-24)
We report here the clinical, genetic and molecular characterization of four Han Chinese families with Leber's hereditary optic neuropathy (LHON). The penetrances of optic neuropathy in these Chinese pedigrees were 38%, 38%, 44% and 56%. This observation is in contrast
H Ramaswamy et al.
The EMBO journal, 9(5), 1561-1568 (1990-05-01)
The originally described integrin beta subunits that define the three subfamilies of integrin heterodimers are beta 1, beta 2 and beta 3. In this paper, we describe the isolation of a cDNA coding for a novel human integrin beta subunit
H Ramaswamy et al.
The EMBO journal, 9(5), 1561-1568 (1990-05-01)
The originally described integrin beta subunits that define the three subfamilies of integrin heterodimers are beta 1, beta 2 and beta 3. In this paper, we describe the isolation of a cDNA coding for a novel human integrin beta subunit
Yuichi Hirasawa et al.
Oncology, 71(1-2), 77-85 (2007-03-08)
To determine the clinical significance of gene promoter methylation in hepatocellular carcinoma (HCC), we examined in clinical samples the methylation status of those promoters that showed elevated activity in hepatoma cell lines after 5-aza-2'-deoxycytidine treatment. Regarding the genes with promoter
Petra H Wirtz et al.
Journal of studies on alcohol and drugs, 71(5), 786-794 (2010-08-25)
The aim of this study was to investigate in heart failure (HF) patients whether acute mental stress induces increases in the HF-severity biomarker B-type natriuretic peptide (BNP) and if alcohol consumption is associated with such stress-induced increases. Twenty-one male HF
C M McIver et al.
Cancer letters, 209(1), 67-74 (2004-05-18)
The aim of this study was to identify tumor-specific markers for the detection of rare disseminated colorectal tumor cells in peripheral venous blood and in intra-peritoneal saline lavage samples collected before and after resection of colorectal tumors. Using cDNA micro-array
K J Park et al.
Clinical radiology, 69(9), 939-944 (2014-05-29)
To investigate the correlation between implant appearance on ultrasound (US) and voiding cystourethrography (VCUG) results after dextranomer-hyaluronic acid copolymer (DxHA) injection in children with vesicoureteral reflux (VUR). Consecutive cases of primary VUR treated by endoscopic subureteral injection of DxHA were
Leonel Maldonado et al.
Oncotarget, 5(14), 5218-5233 (2014-07-02)
By a candidate gene approach, we analyzed the promoter methylation (PM) of 8 genes genes (ARF, TIMP3, RAR-β2, NID2, CCNA1, AIM1, CALCA and CCND2) by quantitative methylation specific PCR (QMSP) in DNA of 17 non-recurrent and 19 recurrent noninvasive low
J D Quigley et al.
Journal of dairy science, 102(9), 8074-8091 (2019-07-22)
The objective of this research was to determine if form of calf starter (CS) and addition of a fatty acid blend (FA) influenced intake, growth, digestion, and indices of immune status and stress in calves from 0 to 4 mo
Eric D Donnenfeld et al.
Journal of cataract and refractive surgery, 47(2), 158-164 (2020-09-15)
To evaluate the safety and efficacy of a nepafenac punctal plug delivery system (N-PPDS) after cataract surgery. Three U.S. clinical sites. Prospective, multicenter, randomized (2:1), parallel-arm, double-masked, placebo-controlled, phase II pilot study. Fifty-six subjects (aged older than 22 years) with
Michael H Gold et al.
Journal of drugs in dermatology : JDD, 11(4), 514-518 (2012-03-29)
Topical antifungal treatment is a mainstay of therapy for Seborrehic Dermatitis (SD). Although the amidazole and ciclopyridine antifungals have been extensively studied, few clinical efficacy data are available for topical allylamine therapy in SD. The objective of this open-label exploratory
Semra Paydas et al.
Leukemia & lymphoma, 48(2), 389-395 (2007-02-28)
Cyclooxygenase 2 (Cox-2) is a key enzyme in prostaglandin synthesis and it has an important role in the pathogenesis of various malignancies. Cox-2 has been studied in solid tumors; however, studies about the role of Cox-2 in non-Hodgkin's lymphomas (NHL)
Ibrahim Bulent Buttanri et al.
Ophthalmic plastic and reconstructive surgery, 29(2), 98-100 (2012-12-14)
To evaluate the effect of suturing the silicone rod to the tarsal plate and the suture material used in suturing on surgical success of frontalis suspension for congenital ptosis. Eighty eyes of 56 consecutive patients who underwent frontalis suspension surgery
Charles R Rosenfeld et al.
American journal of physiology. Heart and circulatory physiology, 296(6), H1878-H1887 (2009-05-28)
Regulation of uteroplacental blood flow (UPBF) during pregnancy remains unclear. Large conductance, Ca(2+)-activated K(+) channels (BK(Ca)), consisting of alpha- and regulatory beta-subunits, are expressed in uterine vascular smooth muscle (UVSM) and contribute to the maintenance of UPBF in the last
Maija E Miettinen et al.
Diabetologia (2021-11-28)
Our aim was to study the association between duration of breastfeeding and circulating immunological markers during the first 3 years of life in children with HLA-conferred susceptibility to type 1 diabetes. We performed a longitudinal analysis of 38 circulating immunological markers
Gergana S Nikolova et al.
Beilstein journal of organic chemistry, 4, 12-12 (2008-10-23)
Sphingolipids belong to the most important constituents of the membranes of eukaryotic cells. As intermediates in sphingolipid metabolism, sphingosine and its N-octadecanoyl-derivative, ceramide, exhibit a variety of biological functions. These compounds play a crucial role in many essential biological processes
A E Ahmed et al.
Journal of biochemical and molecular toxicology, 13(3-4), 119-126 (1999-03-31)
Chloroacetonitrile (CAN) is detected in drinking-water supplies as a by-product of the chlorination process. Gastroesophageal tissues are potential target sites of acute and chronic toxicity by haloacetonitriles (HAN). To examine the mechanism of CAN toxicity, we studied its effect on
Nathalie Angeard et al.
Neuromuscular disorders : NMD, 17(6), 451-458 (2007-04-17)
The objective of this study was to assess the cognitive profile in the childhood-onset form of myotonic dystrophy (DM1). We carried out a general cognitive abilities study on 36 patients (6-18 years). Results of Full Scale IQ , VIQ (Verbal
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