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Showing 1-30 of 57 results for "56-84-8" within Papers
A G A Jackson et al.
Clinical pharmacology and therapeutics, 96(3), 314-323 (2014-05-28)
Rilpivirine long-acting (RPV-LA) is a parenteral formulation enabling prolonged plasma exposure. We explored its multiple-compartment pharmacokinetics (PK) after a single dose, for pre-exposure prophylaxis. Sixty-six HIV-negative volunteers were enrolled: women received an intramuscular dose of 300, 600, or 1,200 mg
Qinghua Nie et al.
BMC genetics, 9, 20-20 (2008-02-29)
With crucial roles on the differentiation of anterior pituitary and the regulation of the prolactin (PRL), growth hormone (GH) and thyroid-stimulating hormone-beta (TSH-beta) genes, the chicken PIT1 gene is regarded as a key candidate gene for production traits. In this
Evan R Goldfischer et al.
Neurourology and urodynamics, 34(1), 37-43 (2013-10-18)
To assess the efficacy and safety of oxybutynin transdermal gel 3% (OTG3%), with propylene glycol for enhanced skin permeation, in patients with urinary incontinence (UI). In this phase 3 study, 626 patients ≥18 years old with urgency and/or mixed UI
Hae Sang Park et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 272(10), 2969-2977 (2014-09-04)
The purpose of this study is to evaluate the feasibility of small intestinal submucosa (SIS) application on the parathyroid autotransplantation in a rat model of hypoparathyroidism. The rats were divided into four groups: NC (no procedure, n = 5), PTX
Andreas H Brunner et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 30(6), 569-575 (2011-10-08)
PAX 8 is a crucial transcription factor for organogenesis of the thyroid gland, kidney, and the Müllerian system and plays an essential role in cell proliferation. The purpose of this study was to evaluate the association between p53 and PAX
D Apter et al.
Clinica chimica acta; international journal of clinical chemistry, 63(2), 139-148 (1975-09-01)
A highly specific method for the determination of cortisol in human serum and urine is described. The sample is first extracted with diethyl ether/ethyl acetate (1 : 1, by vol.), then chromatographed on a highly lipophilic derivative of Sephadex (hydroxyalkoxypropyl
Xinlu Shi et al.
Journal of morphology, 261(1), 43-51 (2004-05-28)
The infraciliature and myoneme system of Campanella umbellaria were revealed using the protargol impregnation technique. The main characteristics of the infraciliature are the peristomial ciliary rows (haplokinety and polykineties), which make four and a half turns around the peristomial disc
Gokhan Kus et al.
In vitro cellular & developmental biology. Animal, 51(10), 1056-1063 (2015-07-15)
Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study investigates the potential for ceranib-2, a novel ceramidase inhibitor, to affect the
Zhan Zhang et al.
Zhonghua fu chan ke za zhi, 45(5), 348-352 (2010-07-22)
To investigate the relationship between human leukocyte antigen-G (HLA-G) gene Exon 8 14 bp deletion polymorphism and the pathogenesis of severe pre-eclampsia. Forty-two pregnant women with severe pre-eclampsia, who admitted to the Third Affiliated Hospital of Zhengzhou University from October
Simon D Lytton et al.
Clinica chimica acta; international journal of clinical chemistry, 415, 346-349 (2012-11-13)
The deamidated gliadin peptides (DGP) cross linked to human tissue transglutaminase (tTg) comprises a novel neo-epitope structure (Neo-tTg) for serological screening of celiac disease (CD). Our aim is to verify anti-Neo-tTg IgA and IgG in adults with dermatitis herpetiformis (DH).
L F Quintana et al.
Kidney international, 69(3), 526-530 (2006-03-04)
The arachidonic acid-derived metabolite 12-(S)hydroxyeicosatetraenoic acid (12(S)-HETE), catalyzed by 12-lipoxygenase (12-LOX, ALOX12), exhibits a variety of biological activities with implications in cardiovascular disease. Previous studies have shown higher urinary excretion of this metabolite in essential hypertension. The aim of this
Shao Hui Huang et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 144, 13-22 (2019-11-12)
This study examines outcome heterogeneity and potential to refine the TNM-8 cN-classification using radiologic extranodal extension (rENE) in a contemporary HPV-positive (HPV+) oropharyngeal carcinoma (OPC) cohort. All HPV+ OPC treated with definitive IMRT from 2010-2015 were included. Pre-treatment CT/MR of
Mikhail Kosiborod et al.
JAMA, 312(21), 2223-2233 (2014-11-18)
Hyperkalemia is a common electrolyte abnormality that may be difficult to manage because of a lack of effective therapies. Sodium zirconium cyclosilicate is a nonabsorbed cation exchanger that selectively binds potassium in the intestine. To evaluate the efficacy and safety
R V Knox et al.
Theriogenology, 82(3), 379-386 (2014-06-04)
Previous studies have shown that triptorelin gel (TG) given intravaginally in gel form is effective for advancing the time of ovulation in weaned sows. Three experiments were performed to determine the effects of altering the dose and timing of administration
Aron D Mosnaim et al.
Neurochemical research, 38(4), 842-846 (2013-02-08)
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78
H Hennemann et al.
European journal of cell biology, 57(1), 51-58 (1992-02-01)
In an attempt to characterize connexin genes expressed early in mouse development we screened a cDNA library from mouse F9 embryonic carcinoma cells with mouse connexin37 cDNA and mouse connexin31.1 genomic DNA under low stringency of hybridization. We detected 5
D Romano et al.
Radiation protection dosimetry (2020-11-19)
Crystalline rocks can produce dangerous radiation levels on the basis of their content in radioisotopes. Here, we report radiological data from 10 metamorphic and igneous rock samples collected from the crystalline basement of the Peloritani Mountains (southern Italy). In order
Nicole R Florance et al.
Annals of neurology, 66(1), 11-18 (2009-08-12)
To report the clinical features of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in patients < or = 18 years old. Information was obtained by the authors or referring physicians. Antibodies were determined by immunocytochemistry and enzyme-linked immunosorbent assay (ELISA) using HEK293 cells
Morgan V Fedorchak et al.
Experimental eye research, 125, 210-216 (2014-07-02)
Treatment of glaucoma by intraocular pressure (IOP) reduction is typically accomplished through the administration of eye drops, the difficult and frequent nature of which contributes to extremely low adherence rates. Poor adherence to topical treatment regimens in glaucoma patients can
Å Collin et al.
The British journal of surgery, 101(12), 1594-1600 (2014-09-11)
A randomized study in 1999-2005 of mechanical bowel preparation (MBP) preceding colonic resection found no decrease in postoperative complications. The aim of the present study was to evaluate the long-term effect of MBP regarding cancer recurrence and survival after colonic
Glen Kristiansen et al.
The American journal of pathology, 161(4), 1215-1221 (2002-10-09)
CD24 is a small heavily glycosylated glycosylphosphatidylinositol-linked cell surface protein, which is expressed in hematological malignancies as well as in a large variety of solid tumors. Very recently its expression in ovarian cancer has been found on RNA level by
Maninder Bedi et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 23(6), 696-700 (2004-09-16)
A polymorphism exists in the tumor necrosis factor alpha (TNF-alpha) promoter (position -308, G/A = TNFA1/TNFA2). The TNFA2 allele is associated with increased TNF-alpha production in vitro and has been reported to increase the risk of allograft rejection in pediatric
Steven S Yu et al.
Clinical genitourinary cancer, 15(6), 742-749 (2017-07-03)
AEZS-108 (zoptarelin doxorubicin) is a cytotoxic hybrid molecule consisting of doxorubicin covalently coupled with a luteinizing hormone-releasing hormone (LHRH) analogue, which selectively targets doxorubicin to tumor cells expressing LHRH receptors. We report the clinical efficacy of AEZS-108 in a phase
Hiroshi Tazawa et al.
Carcinogenesis, 28(1), 191-198 (2006-07-22)
Chronic inflammation is a recognized risk factor for human cancer at various sites because of persistent oxidative and nitrative tissue damage. Trp53+/- mice show the predisposition to tumor development, such as sarcomas and lymphomas, compared with Trp53+/+ mice. We investigated
Koji Izumi et al.
Human pathology, 43(11), 1991-2000 (2012-05-24)
Semenogelins and eppin are seminal plasma proteins that form a complex and inhibit sperm motility. However, the role of these proteins in prostate cancer is poorly understood. We immunohistochemically stained for semenogelins I and II and eppin in 291 radical
Robert A Hauser et al.
Parkinsonism & related disorders, 20(11), 1171-1176 (2014-09-23)
Nausea and vomiting can occur in Parkinson's disease (PD) patients initiated on apomorphine subcutaneous injections and antiemetic prophylaxis is recommended per product labeling. Data suggest long-term antiemetic prophylaxis may not be needed, although this has not been systematically studied. We
Sarah A Holstein et al.
Investigational new drugs, 33(3), 594-602 (2015-02-24)
5-imino-13-deoxydoxorubicin (DIDOX; GPX-150) is a doxorubicin analog modified in two locations to prevent formation of cardiotoxic metabolites and reactive oxygen species. Preclinical studies have demonstrated anti-cancer activity without cardiotoxicity. A phase I study was performed in order to determine the
Samantha J Wojda et al.
Tissue engineering. Part A, 27(3-4), 246-255 (2020-07-04)
Characterizing the release profile for materials-directed local delivery of bioactive molecules and its effect on bone regeneration is an important step to improve our understanding of, and ability to optimize, the bone healing response. This study examined the local delivery
Arantxazu Isla et al.
European journal of clinical pharmacology, 68(5), 735-745 (2012-01-17)
To elucidate whether a dose of 2 g cefoxitin as a prophylactic agent in patients undergoing elective colorectal surgery is able to maintain free drug concentrations above the minimum inhibitory concentration of the microorganisms involved in surgical site infection. This
A Pulkkinen et al.
Metabolism: clinical and experimental, 48(7), 853-856 (1999-07-27)
Hyperinsulinemia has been shown to predict coronary heart disease (CHD) events in both nondiabetic subjects and patients with non-insulin-dependent diabetes mellitus (NIDDM). Therefore, defects in genes that regulate insulin action could be responsible for an increased risk of CHD. The
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