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Showing 1-30 of 56 results for "57-64-7" within Papers
I Fiorini et al.
Journal of medicinal chemistry, 37(10), 1427-1438 (1994-05-13)
A novel class of ligands specific for MBR receptors has been identified: 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives. The majority of newly synthesized esters 37-64 as well as some intermediate ketones showed micro- or nanomolar affinity for [3H]PK 11195 binding inhibition. A SAR study
Jing Zhao et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 671-674 (2012-02-11)
To investigate the detection technology and its clinical significance of the EGFR gene mutation in non-small cell lung cancer. DNA direct sequencing methods by PCR amplification were used to detect EGFR gene exons 18-21 mutation and to analyze its clinical
Xiao-Yong Fu et al.
World journal of gastroenterology, 8(4), 638-643 (2002-08-14)
To investigate the expression of p28/gankyrin gene and its role in the carcinogenetic process of human hepatocellular carcinoma (HCC). 64 specimens of HCC and para-carcinoma tissues, 22 specimens of non-tumor liver tissues (7 normal, 15 cirrhosis), 10 specimens of normal
Yonglan He et al.
Abdominal imaging, 40(8), 3104-3116 (2015-08-20)
To discuss the diverse imaging features of pancreatic and extra-pancreatic lesions of IgG4-related disease (IgG4-RD) on multi-detector CT (MDCT). This retrospective study was approved by our institutional research ethics board, and informed consent was waived. From 2008 to 2013, 159
K McSharry et al.
Alimentary pharmacology & therapeutics, 34(11-12), 1282-1294 (2011-10-18)
BACKGROUND Several published studies have evaluated the efficacy of tacrolimus in the management of Crohn's disease with variable conclusions. AIM To review systematically the evidence examining the efficacy and safety of tacrolimus in treating Crohn's disease. METHODS The Cochrane Central
Ulrike Lass et al.
PloS one, 7(7), e41298-e41298 (2012-07-31)
To investigate the dynamics of inter- and intratumoral molecular alterations during tumor progression in recurrent gliomas. To address intertumoral heterogeneity we investigated non-microdissected tumor tissue of 106 gliomas representing 51 recurrent tumors. To address intratumoral heterogeneity a set of 16
Amanda E Jones et al.
Journal of pediatric and adolescent gynecology, 33(1), 39-44 (2019-09-13)
Describe follow-up care patterns and continuation rates during the first 6 months after initiating a long-acting reversible contraceptive (LARC) device among adolescent and young adult women. Retrospective chart review among patients who had an intrauterine device (IUD) or subdermal implant placed
F Y Chan et al.
Prenatal diagnosis, 21(4), 321-326 (2001-04-05)
Use of the polymerase chain reaction (PCR) for detection of the RHD gene can measure the RHD gene status for unborn babies at risk for hemolytic disease of the newborn (HDN). The occurrence of D gene variants has led to
Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.
P Osterlund et al.
British journal of cancer, 87(6), 591-599 (2002-09-19)
We studied longitudinally inflammatory reactions and serum C-reactive protein (S-CRP) levels in 52 colorectal cancer patients treated with a median of six 3-weekly cycles of raltitrexed 1.5-3.0 mg m(-2) combined with oral carmofur (1-hexylcarbomoyl-5-fluorouracil) 300-400 mg m(-2) on cycle days
Kent W Small et al.
Ophthalmology, 121(4), 952-958 (2014-02-11)
To report a series of cases with fungal endophthalmitis occurring after intravitreal injection of triamcinolone derived from a single lot prepared by a compounding pharmacy. Retrospective, observational case series. Seventeen eyes treated with triamcinolone obtained from a single lot subsequently
Guoqiang Xing et al.
Neuroscience letters, 454(1), 38-42 (2009-05-12)
Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in
Markus Vogt et al.
Virchows Archiv : an international journal of pathology, 458(3), 313-322 (2011-01-13)
The microRNA encoding genes miR-34a and miR-34b/c represent direct p53 target genes and possess tumor suppressive properties as they mediate apoptosis, cell cycle arrest, and senescence. We previously reported that the miR-34a gene is subject to epigenetic inactivation by CpG
Javier P Gisbert et al.
Digestive diseases and sciences, 60(2), 458-464 (2014-09-23)
Helicobacter pylori eradication is a challenge in penicillin allergy. To assess the efficacy and safety of first-line and rescue treatments in patients allergic to penicillin. Prospective multicenter study. Patients allergic to penicillin were given a first-line treatment comprising (a) 7-day
Hasan K Siddiqi et al.
Surgery, 152(6), 1027-1036 (2012-11-20)
Calcium channel blockade with nicardipine (NC) is an alternative to phenoxybenzamine (PB) preparation for resection of a pheochromocytoma. Intraoperative magnesium sulfate infusion (+MgSO(4)) is often used for its cardiovascular stabilizing properties. We hypothesized that preparation with NC would be similar
Eva Barragan et al.
Leukemia research, 31(7), 947-953 (2006-11-23)
Functional polymorphisms in the genes encoding detoxification enzymes could modify the response to treatment in acute myeloid leukemia and therefore affect the final clinical outcome. In the present study, we genotyped 153 patients diagnosed with de novo acute myeloid leukemia
Anna Michniewicz et al.
Applied microbiology and biotechnology, 69(6), 682-688 (2005-06-29)
Cerrena unicolor secreted two laccase isoforms with different characteristics during the growth in liquid media. In a synthetic low-nutrient nitrogen glucose medium (Kirk medium), high amounts of laccase (4,000 U l(-1)) were produced in response to Cu2+. Highest laccase levels
Gabriele Meroni et al.
Microorganisms, 7(12) (2020-01-01)
Staphylococcus pseudintermedius is a commensal bacterium frequently isolated from canine skin and recognized as a zoonotic agent especially for dog-owners. This study focused on (a) the antibiotic-resistance phenotypes; (b) the ability to produce biofilm (slime); and (c) the dissemination of
M Beurg et al.
Biophysical journal, 73(2), 807-818 (1997-08-01)
The Ca2+ currents, charge movements, and intracellular Ca2+ transients of mouse dihydropyridine receptor (DHPR) beta 1-null myotubes expressing a mouse DHPR beta 1 cDNA have been characterized. In beta 1-null myotubes maintained in culture for 10-15 days, the density of
Daren Low et al.
European journal of human genetics : EJHG, 18(11), 1228-1235 (2010-06-24)
Angelman syndrome (AS) is a human neurological disorder caused by lack of maternal UBE3A expression in the brain. UBE3A is known to function as both an ubiquitin-protein ligase (E3) and a coactivator for steroid receptors. Many ubiquitin targets, as well
Tilakavati Karupaiah et al.
Scientific reports, 9(1), 13666-13666 (2019-09-22)
We conducted this cross-sectional population study with a healthy multi-ethnic urban population (n = 577) in Malaysia, combining nutritional assessments with cardiometabolic biomarkers defined by lipid, atherogenic lipoproteins, inflammation and insulin resistance. We found diametrically opposing associations of carbohydrate (246·6 ± 57·7 g, 54·3 ± 6·5%-TEI) and
Zeev Harel et al.
Journal of pediatric and adolescent gynecology, 18(2), 85-90 (2005-05-18)
The new combined estrogen & progestin contraceptive patch Ortho Evra was approved by the FDA in December 2001. To date, there is a paucity of data regarding its use in the adolescent age group. We examined adolescents' experience with this
F I E Najam et al.
Indian journal of pediatrics, 72(9), 745-749 (2005-09-28)
To assess the involvement of complements (C3, C4) in the pathophysiology of bronchial asthma. Selection of patients (n = 64) were made according to the recommended international criteria for diagnosis and classification of asthma. Serum levels of complement components (C3
C E Dammann et al.
Endocrinology, 141(8), 2923-2929 (2000-08-05)
During lung development there is tension between positive and negative regulators of fibroblast-epithelial communication controlling type II cell differentiation. A clinical consequence of imbalance of this tension is the increased risk for respiratory distress syndrome in male infants. We hypothesized
Sheng-Xing Ma et al.
Obesity (Silver Spring, Md.), 19(8), 1560-1567 (2010-12-15)
The purposes of these studies were to quantify the concentrations of total nitrate and nitrite (NO(x)(-)) cyclic guanosine monophosphate (cGMP), and nitrotyrosine over skin surface in normal weight healthy volunteers (n = 64) compared to overweight/obese subjects (n = 54).
H Ludovico-Martins et al.
Transplantation proceedings, 41(3), 862-865 (2009-04-21)
Capillary C4d deposition has been recognized as a marker of antibody-mediated rejection (AMR). Although the detection of capillary C4d by means of immunofluorescence (IF) in cryostat sections is well established, frozen tissue is not always available, thus limiting the diagnosis
Charongpun Musikavong et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(7), 760-771 (2013-03-01)
The characteristic and quantity of dissolved organic matter (DOM) as trihalomethanes precursors in water from the U-Tapao Basin, Songkhla, Thailand was investigated. The sources of water in the basin consisted of two reservoirs and the U-Tapao canal. The canal receives
Maggie C U Cheang et al.
Journal of the National Cancer Institute, 101(10), 736-750 (2009-05-14)
Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B. Luminal B tumors have higher proliferation and poorer prognosis than luminal A tumors. In this study, we
Fabian aus dem Siepen et al.
Clinical research in cardiology : official journal of the German Cardiac Society, 104(8), 640-647 (2015-04-10)
T1 mapping by cardiac magnetic resonance imaging (CMR) is able to determine the extracellular volume fraction. Wild-type transthyretin amyloidosis (WT-ATTR) is characterized by extracellular amyloid deposition in the heart. Recent reports indicated a reduction of left ventricular (LV) myocardial mass
Sameer H Patel et al.
Annals of surgical oncology, 18(12), 3384-3390 (2011-05-19)
Hepatocellular carcinoma (HCC) is a vascular tumor that proliferates through angiogenic pathways mediated, in part, by vascular endothelial growth factor receptor 2 (VEGFR2), and platelet-derived growth factor receptor (PDGFR) α and β. We hypothesized that overexpression of these proteins is
Ronald A Lubet et al.
International journal of cancer, 123(10), 2254-2259 (2008-08-21)
In an initial study to determine if rosiglitazone had chemopreventive activity, Fischer-344 female rats were administered twice weekly doses of hydroxybutyl(butyl)nitrosamine (OH-BBN), a urinary bladder specific carcinogen, for 8 weeks. Two weeks following the last dose of OH-BBN, rats were
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