Search Within


Applied Filters:
Showing 1-30 of 464 results for "608777" within Papers
Manuela Herklotz et al.
Biomaterials, 60, 121-129 (2015-05-20)
To explore the space-filling growth of adherent mesenchymal stem cells (MSC) into tissue-like structures in vitro, human bone marrow derived MSC were exposed to fibronectin-coated, millimeter-sized, triangular channels casted in poly(dimethyl siloxane) carriers. The results revealed that the three dimensional (3D)
Pierre-André Billat et al.
Analytical and bioanalytical chemistry, 407(12), 3449-3456 (2015-02-24)
Ganciclovir (GCV) is prescribed for cytomegalovirus infection which is a major issue in immunodepressed patients. It is however characterized by hematological toxicity. A better understanding of GCV concentration-effects relationships implies the measurement of intracellular forms. The objective of this study
Soxi Lee et al.
Environmental science and pollution research international, 22(12), 9356-9369 (2015-01-21)
Although the aquaculture of spiny lobsters has been expanding since the 1970s, very little is known about the potential environmental impacts on water quality of this activity. This study quantified the production of dissolved inorganic nitrogen (DIN) from Australasian red
R Rodríguez-Gómez et al.
Talanta, 130, 561-570 (2014-08-28)
In recent decades, in parallel to industrial development, a large amount of new chemicals have emerged that are able to produce disorders in human endocrine system. These groups of substances, so-called endocrine disrupting chemicals (EDCs), include many families of compounds
Yossi Shemesh et al.
Nucleosides, nucleotides & nucleic acids, 34(11), 753-762 (2015-10-01)
Carboxylates and dicarboxylates are important phosphate mimics. Herein, we present a simple synthetic route for the preparation of RNA carboxylate/dicarboxylate conjugates, starting from suitably protected NH2- and COOH-containing molecules that are coupled to the RNA on the solid support. The
Susana Sadler Simões et al.
Forensic science international, 243, 117-125 (2014-08-16)
An UPLC-MS/MS method using ESI+ionization and MRM was developed and fully validated according to international guidelines for the qualitative and quantitative analysis of nine synthetic cannabinoids and/or their metabolites in urine samples (1mL). Prior to extraction the samples were subjected
Marion Vallet et al.
Kidney international, 88(1), 137-145 (2015-03-12)
Recent studies suggest that alkalinizing treatments improve the course of chronic kidney disease (CKD), even in patients without overt metabolic acidosis. Here, we tested whether a decreased ability in excreting urinary acid rather than overt metabolic acidosis may be deleterious
Karen Menuz et al.
PLoS genetics, 10(11), e1004810-e1004810 (2014-11-21)
Many insect vectors of disease detect their hosts through olfactory cues, and thus it is of great interest to understand better how odors are encoded. However, little is known about the molecular underpinnings that support the unique function of coeloconic
Guoqiang Liu et al.
Small (Weinheim an der Bergstrasse, Germany), 11(23), 2807-2816 (2015-02-05)
A facile route to fabricate a nanocomposite of Fe3O4@poly[N-isopropylacrylamide (NIPAM)-co-2-(dimethylamino)ethyl methacrylate (DMAEMA)]@Au (Fe3O4@PND@Au) is developed for magnetically recyclable and thermally tunable catalysis. The negatively charged Au nanoparticles with an average diameter of 10 nm are homogeneously loaded onto positively charged
Freimut Schliess et al.
Hepatology (Baltimore, Md.), 60(6), 2040-2051 (2014-03-29)
The impairment of hepatic metabolism due to liver injury has high systemic relevance. However, it is difficult to calculate the impairment of metabolic capacity from a specific pattern of liver damage with conventional techniques. We established an integrated metabolic spatial-temporal
André M P T Pereira et al.
Journal of toxicology and environmental health. Part A, 78(15), 959-975 (2015-08-12)
The growth of aquaculture over the past few years is widely recognized as one of the main sources of antibiotics, mainly fluoroquinolones (FQ) and tetracyclines (TC), in the aquatic environment, consequently, increasing the risk of the emergence of antibiotic bacterial
Aneta Woźniakiewicz et al.
Journal of pharmaceutical and biomedical analysis, 111, 177-185 (2015-04-19)
The aim of the research was to develop a new sensitive method for simultaneously the determination of psychoactive drugs: 1-benzylpiperazine, 7-aminoclonazepam, alprazolam, clonazepam, diazepam, estazolam, lorazepam and tetrazepam in human serum and hair samples. In the preparation step, microwave-assisted extraction
Hamady Dieng et al.
Acta tropica, 145, 68-78 (2015-01-27)
Even with continuous vector control, dengue is still a growing threat to public health in Southeast Asia. Main causes comprise difficulties in identifying productive breeding sites and inappropriate targeted chemical interventions. In this region, rural families keep live birds in
Monika Gibis et al.
Journal of food science, 80(11), C2430-C2439 (2015-10-08)
The impact of precursors such as creatine, creatinine, and glucose on the formation of mutagenic/carcinogenic heterocyclic amines (HAs) were studied in patties of 9 different animal species equally heat treated with a double-plate contact grill. All grilled patties of the
Maria Addolorata Saracino et al.
Journal of pharmaceutical and biomedical analysis, 104, 122-129 (2014-12-17)
A new microextraction by packed sorbent (MEPS) procedure coupled to a high-performance liquid chromatographic method has been developed for quantitation of catecholamines (i.e. norepinephrine, epinephrine and dopamine) in innovative biological samples, namely dried plasma and urine spots. Analyses were carried
Aleksandra Zimmermann et al.
Journal of chromatography. A, 1409, 189-200 (2015-07-25)
A series of new mixed-mode reversed-phase/weak anion-exchange (RP/WAX) phases have been synthesized by immobilization of N-undecenyl-3-α-aminotropane onto thiol-modified silica gel by thiol-ene click chemistry and subsequent introduction of acidic thiol-endcapping functionalities of different type and surface densities. Click chemistry allowed
L Bakhtiari et al.
Materials science & engineering. C, Materials for biological applications, 53, 1-6 (2015-06-05)
Mesoporous hydroxyapatite with different pore diameters and pore volumes were synthesized by the self-assembly method using Cetyltrimethylammonium bromide (CTAB) as the cationic surfactant and 1-dodecanethiol as the pore expander at different micellization pHs, solvent types and surfactant concentrations. Results of
Da-Hye Kim et al.
Environmental pollution (Barking, Essex : 1987), 192, 171-178 (2014-06-24)
Serum and urine samples from 120 children aged 5-13 years from Dae-gu, Korea, were analyzed for 16 perfluorinated compounds (PFCs). The total PFC concentrations in the serum were 4.26-29.70 ng/mL, and perfluorohexanesulfonate (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonate (PFOS, which was dominant
Anne-Kathrin Siemers et al.
Chemosphere, 122, 105-114 (2014-12-09)
Polycyclic aromatic hydrocarbons (PAHs), heterocyclic PAHs (NSO-HETs), alkylated PAHs and phenols are known as the prevailing contaminants in groundwater at tar contaminated sites. Besides these local sources, the concentrations and the distribution in particular of NSO-HETs in environmental samples, such
Jun Ueyama et al.
Environmental health and preventive medicine, 19(6), 405-413 (2014-10-09)
Biological monitoring of organophosphorus insecticide (OP) metabolites, specifically dialkylphosphates (DAP) in urine, plays a key role in low-level exposure assessment of OP in individuals. The aims of this study are to develop a simple and sensitive method for determining four
Michael W Hornung et al.
Toxicological sciences : an official journal of the Society of Toxicology, 146(2), 254-264 (2015-05-09)
As in vitro assays are increasingly used to screen chemicals for their potential to produce endocrine disrupting adverse effects, it is important to understand their predictive capacity. The potential for a set of 6 benzothiazoles to affect endpoints related to thyroid
A Pizzulli et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(10), 1246-1254 (2014-08-12)
Adherence to controller therapy in allergic diseases is low. Telemonitoring has been proposed to improve adherence to treatment in chronic diseases. However, this strategy has never been tested in allergic rhinoconjunctivitis. To test whether Internet-based telemonitoring during the grass-pollen season
Gabriela Andrei et al.
International journal of pharmaceutics, 493(1-2), 16-29 (2015-07-28)
Chitosan gelatin particles could be the ideal candidate for intraocular drug delivery due to their desirable properties. Double crosslinking in double emulsion has been used as an original and reliable method for particles preparation and their morphology has been optimized
Grant A Abernethy
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(9), 1416-1430 (2015-07-04)
This paper proposes a mechanism to explain the trace levels of natural semicarbazide occasionally observed in foods. The analytical derivative of semicarbazide, 2-nitrobenzaldehyde semicarbazone, is often measured as a metabolite marker to detect the widely banned antibiotic nitrofurazone. However, this
Claudia Sánchez et al.
Biotechnology progress, 31(5), 1226-1236 (2015-07-15)
In this work, in silico flux balance analysis is used for predicting the metabolic behavior of Streptomyces clavuligerus during clavulanic acid production. To choose the best objective function for use in the analysis, three different optimization problems are evaluated inside
H Tomšíková et al.
Journal of pharmaceutical and biomedical analysis, 95, 265-272 (2014-04-08)
Elevated levels of pteridines can indicate the activation of cellular immune system by certain diseases. No work dealing with the simultaneous determination of urinary neopterin, biopterin and their reduced forms has been published. Therefore, a new SPE-UHPLC-FD method for the
Varongsiri Kemsawasd et al.
Applied microbiology and biotechnology, 99(23), 10191-10207 (2015-08-11)
In this study, the influence of twenty different single (i.e. 19 amino acids and ammonium sulphate) and two multiple nitrogen sources (N-sources) on growth and fermentation (i.e. glucose consumption and ethanol production) performance of Saccharomyces cerevisiae and of four wine-related
Lina Zuluaga-Idárraga et al.
Journal of pharmaceutical and biomedical analysis, 95, 200-206 (2014-04-01)
One of the most important aspects regarding the therapeutic efficacy of antimalarials is its quantification in biologic fluids. The detection and measurement of antimalarial drug levels is important for demonstrating (1) adequate absorption of the drug being given, (2) compliance
Behnam Behnoush et al.
Medicine, 94(14), e640-e640 (2015-04-11)
The aim of this study was to compare system efficiency and analysis duration regarding the solvent consumption and system maintenance in high-pressure liquid chromatography (HPLC) and ultra high-pressure liquid chromatography (UHPLC). In a case-control study, standard solutions of 7 benzodiazepines
Vernal N Richards et al.
Nuclear medicine and biology, 42(6), 530-535 (2015-03-26)
A proof of concept study was undertaken where non-carrier added (186 g)Re was produced from the cyclotron bombardment of (186)WC. (186)WC was carbo-thermally generated from a novel precursor synthesized from (186)WO3, aqueous ammonia and hexamethyltetramine. The inherent high electrical and
Page 1 of 16