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Showing 1-30 of 123 results for "64-19-7" within Papers
João C Campos et al.
International journal of pharmaceutics, 566, 126-140 (2019-05-28)
Topical drug delivery in the oral mucosa has its set of challenges due to the unique anatomical and physiological features of the oral cavity. As such, the outcomes of local pharmacological treatments in oral disorders can fail due to unsuccessfully
Jennifer Heyl et al.
Journal of cutaneous pathology, 35(1), 40-45 (2007-12-22)
Distinction between sebaceous tumors and basal cell carcinomas can often pose diagnostic problems. Recent work with the antibody to cytokeratin 19 (CK 19) has shown that this marker has high specificity for undifferentiated basaloid cells. Our aim was to evaluate
Maarit Tanskanen et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 18(1), 3-9 (2011-01-26)
Cerebral amyloid angiopathy (CAA) is a frequent finding in the brains of patients with Alzheimer's disease (AD). CAA may be complicated with CAA-associated intracerebral haemorrhage (CAAH). Previous studies have revealed matrix metalloproteinase (MMP) expression in a mouse model of CAA
Geraldo Barroso Cavalcanti et al.
Cytometry. Part B, Clinical cytometry, 78(4), 253-259 (2010-03-04)
p53 is a cell cycle checkpoint control protein that assesses DNA damage and acts as a transcription factor regulating genes, which control cell growth, DNA repair, and apoptosis. p53 mutations have been found in a wide variety of different cancers
Jing Zhao et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 671-674 (2012-02-11)
To investigate the detection technology and its clinical significance of the EGFR gene mutation in non-small cell lung cancer. DNA direct sequencing methods by PCR amplification were used to detect EGFR gene exons 18-21 mutation and to analyze its clinical
Aramati Bindu Madhava Reddy et al.
Molecular vision, 10, 696-702 (2004-10-12)
The human Cytochrome P450 gene CYP1B1 has been implicated in primary congenital glaucoma worldwide. The aim of this study was to understand the role of CYP1B1 mutations in causing primary congenital glaucoma in Indian populations. The study included 64 new
Zamantha Escobedo-Avellaneda et al.
Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 23(2), 185-193 (2016-11-11)
A new approach to the use of high hydrostatic pressure is its combination with high and intermediate temperatures applied to obtain safe foods of high quality. The effect of high hydrostatic pressure on color, residual polyphenol oxidase and pectin methylesterase
Su Bin Kim et al.
Journal of laparoendoscopic & advanced surgical techniques. Part A, 25(10), 793-799 (2015-09-22)
Laparoscopic gastric greater curvature plication (LGGCP) is an emerging, alternative form of restrictive weight loss surgery. We present our experiences of LGGCP with the primary focus on surgical techniques and weight loss. In addition, an investigation was performed on the
Ashu Rastogi et al.
Clinical endocrinology, 79(3), 409-415 (2013-01-26)
Intensive treatment with cabergoline may lead to earlier reduction in prolactin and tumour volume in comparison to conventional schedule. To compare the efficacy and safety of two different dosing schedules of cabergoline in patients with macroprolactinoma. Prospective, randomized trial in
A G Pallis et al.
British journal of cancer, 97(11), 1560-1566 (2007-11-15)
'Classical' mutations in the EGFR tyrosine kinase domain (exons 18, 19 and 21) have been associated with sensitivity to tyrosine kinase inhibitors (TKIs) in patients with NSCLC. The aim of the current study was to evaluate whether other than the
Roger L Snowden
Chemistry & biodiversity, 5(6), 958-969 (2008-07-12)
Using a novel, acid-mediated cyclization methodology, a direct access to Cetalox ((+/-)-1; a commercially important ambergris-type odorant) and various structurally related didehydro (i.e., 19, 26, and 30) and tetradehydro (i.e., 28 and 37/38) analogues is described. Treatment of either (E,E)-14
T Yakut et al.
Genetics and molecular research : GMR, 9(2), 734-738 (2010-05-08)
Angiotensin-converting enzyme (ACE) is a vital enzyme in the renin-angiotensin-aldosterone system, and there are reports in the literature describing its role in the development of cardiovascular system diseases, with I/D polymorphism of the ACE gene. We examined the relationship between
Winnie Fung et al.
Pediatric hematology and oncology, 28(7), 571-578 (2011-07-07)
The clinical hallmark of neuroblastoma is heterogeneity. Biologically, ploidy and N-Myc amplification are currently the only 2 features used to define risk group and to determine therapy. Tyrosine kinase neurotrophin receptors (Trks, including TrkA, TrkB, and TrkC) are important in
J O Boyle et al.
Cancer research, 53(19), 4477-4480 (1993-10-01)
To establish a genetic model of the progression of head and neck squamous carcinoma we have defined the incidence and timing of p53 mutations in this type of cancer. We sequenced the conserved regions of the p53 gene in 102
R C Mathewson et al.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association, 17(6), 835-844 (1997-11-14)
In the differential diagnosis of small round cell tumors (SRCTs), terminal deoxynucleotidyl transferase (TdT) is often used as a marker for lymphoblastic lymphomas and leukemias. However, the specificity of TdT using the avidin-biotin-immunoperoxidase (ABC) method is not well documented. To
Jan Kelder et al.
Steroids, 75(4-5), 314-322 (2010-01-26)
Recent results showing that the binding characteristics of 33 steroids for human membrane progesterone receptor alpha (hu-mPRalpha) differ from those for the nuclear progesterone receptor (nPR) suggest that hu-mPRalpha-specific agonists can be identified for investigating its physiological functions. The binding
Manish M Subramaniam et al.
The American journal of gastroenterology, 104(2), 426-436 (2009-01-29)
We hypothesized that RUNX3 inactivation by promoter hypermethylation in colorectal polyps is an early molecular event in colorectal carcinogenesis. RUNX3 protein expression was analyzed immunohistochemically in 50 sporadic colorectal polyps comprising 19 hyperplastic polyps (HPs), 14 traditional serrated adenomas (TSAs)
Gustavo Luiz Gouvêa de Almeida Junior et al.
Arquivos brasileiros de cardiologia, 115(4), 660-666 (2020-10-29)
COVID-19 causes severe pulmonary involvement, but the cardiovascular system can also be affected by myocarditis, heart failure and shock. The increase in cardiac biomarkers has been associated with a worse prognosis. To evaluate the prognostic value of Troponin-T (TNT) and
Miao-jing Fan et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 679-682 (2012-02-11)
To investigate epidermal growth factor receptor (EGFR) gene mutations in exons 19 and 21 of patients with non-small cell lung cancer (NSCLC) and to analyze the relationship of EGFR mutations with clinicopathological features and prognosis. The EGFR gene exons 19
Y J Zhou et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 32(12), 902-907 (2001-10-13)
Twenty-one 1-[2-[[(substituted-phenyl) methyl] thio]-2-(2, 4-difluorophenyl) ethyl]-1H-1,2,4-triazoles were synthesized and 19 compounds are reported for the first time. Results of biological tests in vitro showed that the antifungal activities of all title compounds were better than or comparable to the activities
Matthew R Smith et al.
Journal of Crohn's & colitis, 8(8), 890-897 (2014-02-11)
The role of mycophenolate mofetil (MMF) as an immunomodulatory drug in managing inflammatory bowel disease (IBD) is yet to be fully defined. We reviewed our experience of MMF in treating patients with IBD. Retrospective analysis was performed on all patients
Mayur Garg et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 16(3), 559-569 (2014-02-08)
The relationship between intestinal inflammation and circulating components of the renin-angiotensin system (RAS) is poorly understood. Demographic and clinical data were obtained from healthy controls and patients with inflammatory bowel disease (IBD). Plasma concentrations of the classical RAS components (angiotensin-converting
Brian J Ward et al.
Lancet (London, England), 396(10261), 1491-1503 (2020-10-17)
Seasonal influenza remains a substantial public health threat despite the availability of egg-derived and other vaccines. Plant-based manufacturing might address some of the limitations of current vaccines. We describe two phase 3 efficacy studies of a recombinant quadrivalent virus-like particle
Ipatia A Doussis-Anagnostopoulou et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(6), 1759-1766 (2008-03-19)
To correlate the immunohistochemical expression of topoisomerase IIalpha (topoIIalpha) in Hodgkin's lymphoma (HL) with clinicopathological parameters, the expression of Ki-67 and the outcome of patients, who had been homogenously treated with ABVD or equivalent regimens. Immunohistochemistry using the monoclonal antibody
Carla Olivieri et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 8(3), 183-190 (2006-03-17)
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterized by the presence of telangiectases and arteriovenous malformations. In some families in whom a form of idiopathic pulmonary arterial hypertension cosegregated with HHT, mutations in the ACVRL1 gene were present.
Hidehisa Saeki et al.
Journal of dermatological science, 30(2), 167-171 (2002-11-05)
We examined polymorphisms of vitamin D receptor (VDR) gene in Japanese patients with psoriasis vulgaris (PsV). We also studied the association between VDR gene polymorphisms and the response to vitamin D (VD) topical treatment in psoriatic patients. FokI, BsmI, ApaI
Matthew P Walters et al.
Journal of clinical pathology, 64(10), 866-869 (2011-07-05)
The BCL-6 proto-oncogene encodes a transcriptional repressor protein. Among normal tissues, BCL-6 expression is confined to germinal center B-cells and a subpopulation of T-helper cells. Little is known about BCL-6 expression in mesenchymal tissues. We examined a series of solitary
G H Ho et al.
Breast cancer research and treatment, 65(3), 225-232 (2001-05-05)
TP53 is the most commonly mutated tumor suppressor gene in human cancers. The amplification and overexpression of HDM2 plays a role in tumorigenesis via inactivation of p53-dependent cell cycle arrest. p14ARF, an alternate transcript of the INK4A tumor suppressor locus
Thomas E Hutson et al.
The Lancet. Oncology, 14(13), 1287-1294 (2013-11-12)
In previous clinical trials of patients with metastatic renal-cell carcinoma, patients treated with axitinib as second-line therapy had longer median progression-free survival than those treated with sorafenib. We therefore undertook a phase 3 trial comparing axitinib with sorafenib in patients
Ahmet Uysal et al.
JPMA. The Journal of the Pakistan Medical Association, 63(11), 1349-1352 (2014-01-08)
To evaluate the effects of a levonorgestrel-releasing intrauterine device in the treatment of adenomyosis associated with heavy menstrual bleeding. The retrospective study was conducted at a tertiary referral hospital in Izmir, Turkey, and comprised data on adenomyosis patients who were
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