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bioactive small molecules (2)
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64984-31-2
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Pifithrin-μ
Synonym(s):
2-Phenylethynesulfonamide, PFTμ, Pifithrin-μ
Empirical Formula (Hill Notation):
C
8
H
7
NO
2
S
CAS No.:
64984-31-2
Molecular Weight:
181.21
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Description
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P0122
≥97% (HPLC), solid
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506155
A cell-permeable sulfonamide that blocks p53 interaction with Bcl-xL and Bcl-2 proteins and selectively inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.
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