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66-22-8
Keyword:'66-22-8'
Showing 1-30 of 86 results for "66-22-8" within Papers
Journal of biomolecular NMR, 69(3), 111-121 (2017-11-17)
The structure of monomeric human chemokine IL-8 (residues 1-66) was determined in aqueous solution by NMR spectroscopy. The structure of the monomer is similar to that of each subunit in the dimeric full-length protein (residues 1-72), with the main differences
The Journal of investigative dermatology, 130(6), 1537-1542 (2010-01-08)
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder that is associated with an inherited defect of the nucleotide excision repair pathway (NER). In this study, we investigated the involvement of XP genes in 86 XP patients belonging to 66
Irish medical journal, 105(10), 335-338 (2013-03-19)
The provision of specialist palliative care to Irish patients suffering from motor neurone disease has not been described in the literature. The purpose of this study was to characterize the care provided at a Dublin hospice. Consecutive referrals between 1st
Langmuir : the ACS journal of surfaces and colloids, 20(24), 10534-10541 (2004-11-17)
Surface tension isotherms were recorded for n-decyl-beta-d-glucopyranoside (Glu) and n-decyl-beta-D-maltopyranoside (Mal) solutions at temperatures of 8, 22, and 29 degrees C. Comparison was made with isotherms of n-decyl-beta-D-thiomaltopyranoside (S-Mal) at 22 degrees C. In addition to the transition from the
Pediatric blood & cancer, 62(8), 1368-1373 (2015-05-06)
The clinical significance of minimal residual disease (MRD) detected by real-time quantitative PCR (qPCR) in autologous stem cell grafts in high risk neuroblastoma is still controversial. In this retrospective multicenter study, autologous stem cell grafts of a large cohort were
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 24(24), 1105-1107 (2011-03-15)
To investigate the expression of DNMT1 in laryngeal squamous cell carcinoma (LSCC) and its relationship with clinicopathological factors. Ninety-six cases of LSCC samples were detected by immunohistochemical staining to analyze the expression of DNMT1 protein, while 66 cases of them
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 109(4), 548-553 (2010-02-27)
We hypothesized that, similar to idiopathic hip osteonecrosis, the T-786C mutation of the endothelial nitric oxide synthase (eNOS) gene affecting nitric oxide (NO) production was associated with neuralgia-inducing cavitational osteonecrosis of the jaws (NICO). In 22 NICO patients, not having
Food additives & contaminants. Part B, Surveillance, 7(2), 151-155 (2014-06-11)
A total of 232 samples of corn commercialised in Santa Catarina state, Southern Brazil (temperate zone climate), were evaluated from 2007 to 2012 for fumonisins (FBs: FB1 and FB2). Before performing this study, a FBs method with liquid chromatography and
Physiological genomics, 23(1), 28-45 (2005-06-30)
Interferon gamma (IFN-gamma) plays a role in a variety of lung inflammatory responses, and corticosteroids are frequently employed as a treatment in these conditions. Therefore, the effect of IFN-gamma, of the corticosteroid dexamethasone (Dex), or of both on gene expression
Pflugers Archiv : European journal of physiology, 452(3), 316-323 (2006-01-18)
Non-synonymous single nucleotide polymorphisms (SNPs) in the KCNA5/hKv1.5 gene, which encodes for a voltage-gated K+ channel responsible for the I (Kur) current in the human atria, have been recently reported. To gain further knowledge on potential influence of hKv1.5 SNPs
Archives of toxicology, 86(10), 1593-1601 (2012-05-12)
Estragole (ES) is a natural organic compound used frequently as a flavoring food additive. Although it has been reported to be tumorigenic and induce DNA adducts in the mouse liver, there have been no reports regarding ES hepatocarcinogenicity in rats.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 130(1), 27-30 (2015-04-29)
To assess ARID1A-encoded protein (BAF250a) and phosphorylated AKT (pAKT) expression, apoptosis, and the DNA damage response pathway in endometrioid and clear cell ovarian cancers (endometriosis-associated ovarian cancers [EAOCs]), and benign endometriotic ovarian cysts. In a retrospective study, tissue samples were
Investigational new drugs, 33(4), 985-991 (2015-06-19)
This study investigated the activity of MK-2206, an AKT inhibitor, in metastatic or recurrent nasopharyngeal carcinoma (NPC). Oral MK-2206 at a dose of 200 mg was administered on days 1, 8, 15 and 22 of a 28-day cycle until progression.
Mayo Clinic proceedings, 86(10), 948-955 (2011-10-04)
To evaluate the efficacy of MAP0004, an orally inhaled dihydroergotamine, for acute treatment of migraine when administered at various time points from within 1 hour to more than 8 hours after migraine onset. This post hoc subanalysis was conducted using
The pharmacogenomics journal, 18(2), 215-226 (2017-07-19)
Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common single-nucleotide polymorphisms (SNPs) modified the association between thiazide use and QT or its
The British journal of radiology, 85(1017), e748-e755 (2012-03-17)
The objective of this study was to determine the optimal scan delay quantitatively and qualitatively in cerebral CT angiography (CTA) with a test injection method at the circle of Willis (cW). 66 consecutive patients suspected of having unruptured intracranial aneurysms
Clinical and experimental rheumatology, 22(1), 85-90 (2004-03-10)
To evaluate the role of aging and specific cytokine blockade in the etiology of cachexia caused by adjuvant arthritis (AA), a model of cytokine-associated cachexia. AA was induced in Lewis rats using CFA. In Experiment 1, severity of AA and
Cancer, 121(3), 432-440 (2014-09-25)
Aberrant Notch activation confers a proliferative advantage to many human tumors, including melanoma. This phase 2 trial assessed the antitumor activity of RO4929097, a gamma-secretase inhibitor of Notch signaling, with respect to the progression-free and overall survival of patients with
The Journal of physiology, 460, 1-13 (1993-01-01)
1. Myotubes were grown in culture from normal (C57BL/ScSn) and mdx mice and the cytosolic [Ca2+] was monitored through development (5-21 days in culture) using fura-2 loaded via ionophoresis. Simultaneous measurements of the membrane potential and cytosolic [Ca2+] were made
The British journal of nutrition, 1-11 (2022-02-12)
Low birth weight (LBW) neonates show impaired growth compared with normal birth weight (NBW) neonates. Glutamine (Gln) supplementation benefits growth of weaning piglets, while the effect on neonates is not sufficiently clear. We examined the effect of neonatal Gln supplementation
Nephron. Experimental nephrology, 105(4), e117-e123 (2007-03-10)
Diabetic nephropathy (DN) is one of the most important microvascular complications of diabetes mellitus. However, the underlying mechanisms remain unclear. We studied the expression characteristics of angiopoietin-like 2 (ANGPTL2), a novel DN-associated growth factor identified in our previous gene chip
Clinical endocrinology, 82(5), 657-662 (2015-01-20)
It is unclear whether the rate of vitamin D deficiency in paediatric cancer survivors is higher than in the background population, and whether this is of pathological significance. 25OHD was measured in a previously studied group of 208 survivors (n
Clinical and experimental immunology, 177(1), 310-319 (2014-03-13)
Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is characterized by persisting mucoid biofilms in hypoxic endobronchial mucus. These biofilms are surrounded by numerous polymorphonuclear leucocytes (PMNs), which consume a major part of present molecular oxygen (O(2)) due
Biology of reproduction, 67(4), 1321-1326 (2002-09-26)
Calcitonin gene-related peptide (CGRP), one of the most potent vasodilators known, exerts its biological action by interacting with its receptors. Recent reports suggest the existence of two types of CGRP receptors, CGRP-A and CGRP-B. The current study was designed to
Journal of cancer research and clinical oncology, 140(5), 829-837 (2014-02-22)
We conducted a multicenter phase II study to assess the toxicity and efficacy of a combination of mitomycin C (MMC) and capecitabine in pretreated patients with metastatic or locally advanced gastric cancer. Thirty-nine patients (77 % male) between 33 and
Sleep medicine, 14(1), 30-36 (2012-10-06)
Mazindol is a tricyclic, anorectic, non-amphetamine stimulant used in narcolepsy and obesity since 1970. This study aimed to evaluate the long-term benefit/risk ratio in drug-resistant hypersomniacs and cataplexy sufferers. By retrospective analysis of the patients' files in the hospitals of
The British journal of dermatology, 167(6), 1279-1286 (2012-07-28)
Paraoxonase 1 (PON1) is a serum high-density lipoprotein-bound enzyme with antioxidant function. It hydrolyses lipid peroxides, protecting low-density lipoproteins from oxidative modifications. Patients with psoriasis are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism.
Stereotactic and functional neurosurgery, 86(4), 245-252 (2008-05-15)
To study stereotactic magnetic resonance imaging (MRI) features of the basal ganglia in DYT1 primary dystonia. Twenty-five genetically confirmed DYT1 dystonia patients (age range, 8-66 years; mean age, 22 years) underwent brain MRI under general anesthesia at the time of
European journal of clinical nutrition, 55(2), 88-96 (2001-04-18)
To determine whether healthy males who consumed increased amounts of dietary stearic acid compared with increased dietary palmitic acid exhibited any changes in their platelet aggregability, platelet fatty acid profiles, platelet morphology, or haemostatic factors. A randomized cross-over dietary intervention.
Proceedings of the National Academy of Sciences of the United States of America, 99(26), 16975-16980 (2002-12-12)
We have identified a gene located on chromosomes 21 that is expressed in normal and neoplastic prostate, and in normal testis, ovary, and placenta. We name this gene POTE (expressed in prostate, ovary, testis, and placenta). The POTE gene has
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