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Showing 1-30 of 147 results for "67-64-1" within Papers
B K Michelsen et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(19), 8754-8758 (1991-10-01)
A 64-kDa islet protein is a major autoantigen in insulin-dependent diabetes mellitus (IDDM). Autoantibodies against the 64-kDa protein were recently shown to immunoprecipitate glutamic acid decarboxylase (GAD; L-glutamate 1-carboxy-lyase, EC 4.1.1.15) from brain and from islets. We present evidence that
Yun-Ge Zhao et al.
Molecular reproduction and development, 62(2), 149-158 (2002-05-02)
Zymography and in situ hybridizition were used to investigate matrix metalloproteinase-2, -9 (MMP-2, -9) activities, and expression of mRNAs for MMP-2, -9 and tissue inhibitors of matrix metalloproteinases (TIMP-1, -2, -3) in the rat uterus during early pregnancy (day 1-7).
S I Goodman et al.
European journal of biochemistry, 219(1-2), 277-286 (1994-01-15)
Electron-transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The two redox centers in the protein, FAD and a [4Fe4S]+2,+1 cluster
Ann E Walts et al.
Histopathology, 78(5), 699-709 (2020-10-08)
To gather the best available evidence regarding Ki-67% values in large-cell neuroendocrine carcinoma (LCNEC) and determine whether certain cut-off values could serve as a prognostic feature in LCNEC. Aperio ScanScope AT Turbo, eSlide Manager and ImageScope software (Leica Biosystems) were
L A Bass et al.
Bioconjugate chemistry, 11(4), 527-532 (2000-07-18)
An understanding of the metabolic fate of radiometal-labeled peptides is important due to their application in the areas of diagnostic imaging and targeted radiotherapy. Radioisotopes of copper ((64)Cu, T(1/2) = 12.7 h; (67)Cu, T(1/2) = 62 h) have been labeled
L A Matiasek et al.
Journal of veterinary internal medicine, 23(1), 146-151 (2009-01-30)
Tumor proliferation in human intracranial meningiomas can be defined by the reactivity of the monoclonal antibody MIB-1 to the Ki-67 antigen. Vascular endothelial growth factor (VEGF), a pro-angiogenic factor, is a predictive marker for survival of dogs with intracranial meningiomas.
Morihiko Inamine et al.
International journal of clinical oncology, 17(5), 498-504 (2011-09-29)
Vascular endothelial growth factors (VEGFs) are involved in angiogenesis, but molecular links to the most important etiological agents, human papillomavirus (HPV) and smoking, need to be clarified. Archival samples at the first diagnosis of 64 cervical intraepithelial neoplasia grade 1
Vanitha Sivalingam et al.
Lancet (London, England), 385 Suppl 1, S90-S90 (2015-08-28)
Metformin use is associated with reduced cancer risk in several observational studies of patients with type 2 diabetes. Results from preclinical studies in endometrial cancer show that metformin reduces cellular proliferation by inhibition of the PI3K-AKT-mTOR pathway. We tested the
Aysen Terzi et al.
Pathology, research and practice, 204(5), 305-314 (2008-04-01)
Although histologic grading of meningiomas has prognostic and clinical implications, it is difficult in some cases to predict the outcome of patients. There have been several efforts to evaluate the use of different immunohistochemical markers for predicting meningioma prognosis. We
Song Xue et al.
Oncotarget, 8(30), 49702-49712 (2017-06-08)
Programmed death ligand 1 (PD-L1) is highly expressed in many cancers. We investigated the expression of PD-L1 and its relationship with vascular endothelial growth factor (VEGF), matrix metalloproteinase-9 and KI-67 expression in 64 patients with primary glioma. The expression rate
Marta Ferraroni et al.
Biochemistry, 41(20), 6237-6244 (2002-05-16)
The human genetic variant carbonic anhydrase I (CA I) Michigan 1 results from a single point mutation that changes His 67 to Arg in a critical region of the active site. This variant of the zinc metalloenzyme appears to be
Ipatia A Doussis-Anagnostopoulou et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(6), 1759-1766 (2008-03-19)
To correlate the immunohistochemical expression of topoisomerase IIalpha (topoIIalpha) in Hodgkin's lymphoma (HL) with clinicopathological parameters, the expression of Ki-67 and the outcome of patients, who had been homogenously treated with ABVD or equivalent regimens. Immunohistochemistry using the monoclonal antibody
Edward L Engelhardt et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 43(6), 837-850 (2002-06-07)
The cyclam ligand (1,4,8,11-tetraazacyclotetradecane) was condensed with various azomycin-containing synthons to produce chemical compounds that could chelate radioactive metals. It was expected that these radiolabeled markers would become bound selectively to hypoxic cells on the bioreduction of their azomycin substituent.
Mel C Heeran et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 121(12), 1177-1186 (2013-04-19)
The primary objective of this study was to assess the expression of MIB-1 (Ki-67) in tumour tissues from 808 patients with epithelial ovarian tumours. The second was to evaluate, whether MIB-1 (Ki-67) tissue expression levels correlate with clinicopathological parameters and
Elena Ricart et al.
The American journal of gastroenterology, 97(7), 1763-1768 (2002-07-24)
5-Aminosalicylate is metabolized in colonic mucosa by N-acetyltransferase 1 (NAT1), and sulfapyridine is metabolized in the liver by N-acetyltransferase 2 (NAT2). Common genetic polymorphisms in these enzymes result in rapid and slow acetylation. We determined the association between NAT1 genotype
Tomiko Kawakami et al.
International journal of molecular medicine, 20(2), 177-185 (2007-07-06)
Insulinoma-associated protein (IA)-2 beta, an inactive member of the protein-tyrosine phosphatase (PTP) family, is a major autoantigen in type-1 diabetes mellitus. IA-2 beta exists mainly in a 60-kDa form, and is frequently located in the dense-core secretory vesicles of pancreatic
Masaaki Ichinoe et al.
Pathology, research and practice, 211(7), 533-538 (2015-04-25)
L-Type amino acid transporter 1 (LAT1) is one of the major amino acid transporters. High levels of LAT1 expression have been reported in various tumors, which can act as a novel prognostic marker. Previously, we demonstrated that LAT1 is highly
B Tanner et al.
Biochimica et biophysica acta, 1171(3), 319-320 (1993-01-23)
A complementary DNA has been cloned and sequenced for the mouse extracellular signal regulated kinase (erk-1). The nucleotide sequence of the 1.7 kb mouse erk-1 cDNA clone (merk-1-34) is 93.5% identical to the published rat DNA sequence (Boulton et al.
Cleiton A Libardi et al.
Clinical physiology and functional imaging, 35(4), 245-249 (2014-05-07)
The aim of this study was to investigate the effects of the ageing process in the electromechanical delay (EMD), rate of torque development (RTD) and peak torque (PT) of the knee extensor muscles. The volunteers were assigned to three groups:
Ian M Bovio et al.
American journal of clinical pathology, 130(4), 628-634 (2008-09-17)
We retrospectively studied the immunophenotype by flow cytometry of 20 anaplastic large cell lymphomas (ALCLs) (9 anaplastic lymphoma kinase [ALK]+ and 11 ALK-) with a particular emphasis on the aberrant expression of the myeloid associated antigens CD13 and/or CD33. All
Niels Peter Rønnow Sand et al.
JACC. Cardiovascular imaging, 13(4), 994-1004 (2019-08-20)
This study was designed to compare head-to-head fractional flow reserve (FFR) derived from coronary computed tomography angiography (CTA) (FFRCT) and cardiac magnetic resonance (CMR) stress perfusion imaging for prediction of standard-of-care-guided coronary revascularization in patients with stable chest pain and
Sayid Shafi Zuhur et al.
Neuro endocrinology letters, 36(2), 165-170 (2015-06-14)
To determine immunohistochemical expression of Eag1 in pituitary adenomas of patients with acromegaly and to assess the correlation between Eag1 expression with cavernous sinus invasion, tumoral Ki-67 labeling index (LI), age and gender of the patients. The paraffin embedded pituitary
Mohammad Abd Alkhalik Basha et al.
Abdominal radiology (New York), 44(5), 1773-1784 (2019-01-04)
We investigated the added value of diffusion-weighted imaging (DWI)/apparent diffusion coefficient (ADC) in the categorization of small hepatic observation (≤ 20 mm) detected in patients with chronic liver disease in reference to LI-RADS (liver imaging reporting and data system) classification system. We
H Cao Danh et al.
The Journal of pharmacy and pharmacology, 37(5), 357-361 (1985-05-01)
Eye MAO-A, MAO-B, semicarbazide-sensitive amine oxidase (SSAO) and aldehyde reductase (AR) activities were measured in young and old rats. When enzyme activity is expressed as nmol (mg protein)-1 min-1, a significant decrease (18-23%) of SSAO activity in the eye of
Hyun-Seock Shin et al.
Biochemical and biophysical research communications, 385(2), 273-278 (2009-05-23)
The human ribosomal protein S3 (rpS3), a component of the 40S small subunit in the ribosome, is a known multi-functional protein with roles in DNA repair and apoptosis. We recently found that the arginine residue(s) of rpS3 are methylated by
A M Patwardhan et al.
Journal of dental research, 87(3), 262-266 (2008-02-26)
Orofacial inflammation is associated with prostaglandin release and the sensitization of nociceptive receptors such as the transient receptor potential subtype V(1) (TRPV(1)). We hypothesized that certain PGE(2) receptor subtypes (EP1-EP4) are co-expressed with TRPV(1) in trigeminal nociceptors and sensitize responses
Audrey Deeken-Draisey et al.
Human pathology, 82, 140-148 (2018-08-04)
Anaplastic thyroid carcinoma (ATC) is a highly aggressive form of thyroid cancer. A single-institution thyroid cancer cohort of ATC was identified within the last 10 years at our institution. Retrospective analysis revealed that the frequency of ATC was 0.5% (11/2106
P J Hoskin et al.
British journal of cancer, 89(7), 1290-1297 (2003-10-02)
Glucose transporter-1 protein (GLUT1) and carbonic anhydrase IX (CAIX) are regulated by hypoxia inducible factor-1 (HIF-1) and have been studied as putative intrinsic cellular markers for hypoxia. This study directly compares CAIX and GLUT1 with pimonidazole binding in a prospective
Tadashi Hasegawa et al.
Human pathology, 44(7), 1271-1277 (2013-01-08)
Previously, we showed that the expression of potassium channel tetramerization domain-containing 12 (KCTD12), which was discovered by a proteomics approach, is associated with high-risk behavior of gastrointestinal stromal tumors (GISTs). Here, we examined the distribution and expression of this protein
Mihir Tanay Das et al.
Environmental pollution (Barking, Essex : 1987), 189, 118-125 (2014-03-25)
An indirect estimation method was followed to derive exposure levels of fifteen phthalate congeners in urban population of Delhi, India. The exposure media samples were collected from Jawaharlal Nehru University (JNU) campus and Okhla industrial area. GC-MS analysis of the
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