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Showing 1-30 of 556 results for "708860" within Papers
Sandra Giovanoli et al.
Journal of neuroinflammation, 12, 221-221 (2015-11-26)
Prenatal exposure to infection and/or inflammation is increasingly recognized to play an important role in neurodevelopmental brain disorders. It has recently been postulated that prenatal immune activation, especially when occurring during late gestational stages, may also induce pathological brain aging
Elena Brezina et al.
Environmental science & technology, 49(17), 10449-10456 (2015-08-25)
Carbamazepine (CBZ) is a worldwide used antiepileptic drug, which is metabolized to a large extent in the human body to several metabolites, including 10,11-dihydroxy-10,11-dihydrocarbamazepine (DiOHCBZ), 2-hydroxycarbamazepine (2OHCBZ), and 3-hydroxycarbamazepine (3OHCBZ). 2OHCBZ and 3OHCBZ were previously detected in raw and treated
Timothy K Amukele et al.
PloS one, 10(7), e0134020-e0134020 (2015-07-30)
Unmanned Aerial Systems (UAS or drones) could potentially be used for the routine transport of small goods such as diagnostic clinical laboratory specimens. To the best of our knowledge, there is no published study of the impact of UAS transportation
Judyta Cielecka-Piontek et al.
Pharmaceutical development and technology, 20(2), 146-152 (2013-11-14)
The kinetic and thermodynamic parameters of degradation of clavulanate potassium in the solid state were studied by using a reversed phase high performance liquid chromatography (RP-HPLC) method. The degradation of clavulanate potassium was a first-order reaction depending on the substrate
Xinying Zhou et al.
Journal of hepatology, 61(4), 746-754 (2014-05-27)
Humans are frequently exposed to hepatitis E virus (HEV). Nevertheless, the disease mainly affects pregnant women and immunocompromised individuals. Organ recipients receiving immunosuppressants, such as rapalogs, to prevent rejection have a high risk for developing chronic hepatitis following HEV infection.
Mohammad Parwez Ahmad et al.
Pakistan journal of pharmaceutical sciences, 28(2), 509-513 (2015-03-03)
Lipopolysaccharide (LPS) induced oxidative stress and impairment of normal physiological function generally categorized by increased anxiety and reduced mobility. Therefore, the present study was to find out the effect Methanolic extract of Asparagus racemosus (MEAR ) in lipopolysaccharide (LPS)-induced oxidative
Sindy Cole et al.
Scientific reports, 5, 16143-16143 (2015-11-06)
The orexin/hypocretin system is important for reward-seeking behaviors, however less is known about its function in non-homeostatic feeding. Environmental influences, particularly cues for food can stimulate feeding in the absence of hunger and lead to maladaptive overeating behavior. The key
Burak Derkus et al.
Materials science & engineering. C, Materials for biological applications, 56, 132-140 (2015-08-08)
This study investigates effective immobilization of proteins, an important procedure in many fields of bioengineering and medicine, using various biomaterials. Gelatin, alginate and chitosan were chosen as polymeric carriers, and applied in both their composites and nanocomposite forms in combination
L W Rottman et al.
Journal of dairy science, 98(7), 4673-4684 (2015-05-04)
Dairy cows exhibit a daily pattern of feed intake and milk synthesis, and feeding a single total mixed ration over the day may not synchronize ruminal fermentation, nutrient absorption, and milk synthesis. Our hypothesis was that feeding a high-fiber diet
Yuwadee Boonyasit et al.
Analytical and bioanalytical chemistry, 407(18), 5287-5297 (2015-05-10)
We propose a novel alternative approach to long-term glycaemic monitoring using eggshell membranes (ESMs) as a new immobilising platform for the selective label-free electrochemical sensing of glycated haemoglobin (HbA1c), a vital clinical index of the glycaemic status in diabetic individuals.
Milena K Bulla et al.
Photochemistry and photobiology, 91(3), 558-566 (2015-01-13)
Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to
Shih-Wey Yeh et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(45), 16035-16046 (2015-09-26)
As opposed to the reversible redox reaction ({Fe(NO)2 }(10) reduced-form DNIC [(NO)2 Fe(S(CH2 )3 S)](2-) (1)⇌{Fe(NO)2 }(9) oxidized-form [(NO)2 Fe(S(CH2 )3 S)](-) ), the chemical oxidation of the {Fe(NO)2 }(10) DNIC [(NO)2 Fe(S(CH2 )2 S)](2-) (2) generates the dinuclear {Fe(NO)2
Synthesis of heterobifunctional polyethylene glycols: Polymerization from functional initiators
Vojkovsky T, et al.
Polymer, 105(27), 72-78 (2016)
Jelena Culej et al.
Molecular biology reports, 42(2), 553-558 (2014-11-07)
Serotonin transporter polymorphism (5-HTTLPR) is a well-studied polymorphism in psychiatric research. The function of serotonin transporter is to control neural stimulation and maintain homeostasis of serotonin in other cells like platelets and enterochromaffin cells. Considering serotonin function in human behavior
Alan A Cohen et al.
PloS one, 10(4), e0122541-e0122541 (2015-04-16)
Physiological dysregulation may underlie aging and many chronic diseases, but is challenging to quantify because of the complexity of the underlying systems. Recently, we described a measure of physiological dysregulation, DM, that uses statistical distance to assess the degree to
Saleh Yazdani et al.
Disease models & mechanisms, 8(8), 919-930 (2015-06-03)
Proteinuria is an important cause of tubulointerstitial damage. Anti-proteinuric interventions are not always successful, and residual proteinuria often leads to renal failure. This indicates the need for additional treatment modalities by targeting the harmful downstream consequences of proteinuria. We previously
Youngtae Jeong et al.
Molecular cancer therapeutics, 14(8), 1951-1961 (2015-05-03)
The anticancer actions of vitamin D and its hormonally active form, calcitriol, have been extensively documented in clinical and preclinical studies. However, the mechanisms underlying these actions have not been completely elucidated. Here, we examined the effect of dietary vitamin
Zhenyu Xiao et al.
Cancer letters, 360(2), 302-309 (2015-02-28)
Human hepatocellular carcinoma (HCC) has a high rate of tumor recurrence and metastasis, resulting in shortened survival times. The efficacy of current systemic therapies for HCC is limited. In this study, we used xenograft tumor models to investigate the use
Caroline M Lai et al.
The Journal of infectious diseases, 211(3), 383-393 (2014-08-26)
Viruses that cause systemic disease often spread through the bloodstream to infect target tissues. Although viremia is an important step in the pathogenesis of many viruses, how viremia is established is not well understood. Reovirus has been used to dissect
D E Rico et al.
Journal of dairy science, 97(9), 5637-5644 (2014-07-16)
A variable response to fat supplementation has been reported in dairy cows, which may be due to cow production level, environmental conditions, or diet characteristics. In the present experiment, the effect of a high palmitic acid supplement was investigated relative
D Fan et al.
Oncogene, 34(16), 2083-2093 (2014-06-10)
Leukemic lymphoblasts within different immunophenotypic populations possess stem cell properties. However, whether or not the self-renewal program is retained from stem cells or conferred on progenitors by leukemogenic molecules remains unknown. We have addressed the issue in the context of
Xikuang Yao et al.
Biomacromolecules, 16(7), 2059-2071 (2015-05-30)
Cisplatin-incorporating pseudoblock copolymer nanoparticles with high drug loading efficiency (ca. 50%) were prepared built on host-guest inclusion complexation between β-cyclodextrin end-capped poly(N-vinylpyrrolidone) block and admantyl end-capped poly(aspartic acid) block, followed by the coordination between cisplatin and carboxyl groups in poly(aspartic
Katja Grabowski et al.
PloS one, 10(2), e0116807-e0116807 (2015-02-04)
Reactivation of fetal gene expression patterns has been implicated in common cardiac diseases in adult life including left ventricular (LV) hypertrophy (LVH) in arterial hypertension. Thus, increased wall stress and neurohumoral activation are discussed to induce the return to expression
S Hassanpour et al.
British poultry science, 56(4), 443-451 (2015-06-09)
The aim of the current study was to investigate the interaction of the nitric oxide and cannabinoidergic systems on feeding behaviour in neonatal chicken. A total of 6 experiments were designed to evaluate the interaction between cannabinoidergic and nitrergic systems
Melanie Morales et al.
Tree physiology, 35(3), 253-265 (2015-03-15)
The physiological response of plants growing in their natural habitat is strongly determined by seasonal variations in environmental conditions and the interaction of abiotic and biotic stresses. Here, leaf water and nutrient contents, changes in cellular redox state and endogenous
Poulomee Bose et al.
Peptides, 73, 43-50 (2015-08-25)
Neurotensin (NT) is an endogenous neuropeptide that modulates dopamine and glutamate neurotransmission in several limbic regions innervated by neurons located in the ventral tegmental area (VTA). While several studies showed that NT exerted a direct modulation on VTA dopamine neurons
Meng-Chieh Hsu et al.
Reproduction (Cambridge, England), 147(6), 835-845 (2014-02-26)
Kisspeptin acts as an upstream regulator of the hypothalamus-pituitary-gonad axis, which is one of the main regulatory systems for mammalian reproduction. Kiss1 and its receptor Kiss1r (also known as G protein-coupled receptor 54 (Gpr54)) are expressed in various organs, but
Janette Kropat et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(9), 2644-2651 (2015-02-04)
Inorganic elements, although required only in trace amounts, permit life and primary productivity because of their functions in catalysis. Every organism has a minimal requirement of each metal based on the intracellular abundance of proteins that use inorganic cofactors, but
Kazuhito Goda et al.
Microscopy research and technique, 78(8), 715-722 (2015-06-23)
Bioluminescence microscopy has revealed that gene expression in individual cells can respond differently to the same stimulus. To understand this phenomenon, it is important to sequentially observe the series of events from cellular signal transduction to gene expression regulated by
Yasuto Kinose et al.
Oncotarget, 6(13), 11342-11356 (2015-04-04)
During the dissemination of ovarian cancer cells, the cells float in the peritoneal cavity without access to a vascular supply and so are exposed to hypoxic conditions, which may cause the ovarian cancer cells to acquire a more aggressive and
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